Nirupam De, Choong Eui Song, Do Hyun Ryu and Eun Jeong Yoo
Chem. Commun., 2018,54, 6911-6914
DOI:
10.1039/C8CC02570C,
Communication
Herein, we demonstrate a new catalytic cycloaddition of quinolinium zwitterions involving a gold-bound allylic cation intermediate. This ligand-free higher-order cycloaddition efficiently affords a variety of fused 1,4-diazepine derivatives in a stereospecific manner at room temperature.
![Graphical abstract: Gold-catalyzed [5+2] cycloaddition of quinolinium zwitterions and allenamides as an efficient route to fused 1,4-diazepines](/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=C8CC02570C "Graphical abstract")