Issue 2, 2016

Cancer screening via infrared spectral cytopathology (SCP): results for the upper respiratory and digestive tracts

Abstract

Instrumental advances in infrared micro-spectroscopy have made possible the observation of individual human cells and even subcellular structures. The observed spectra represent a snapshot of the biochemical composition of a cell; this composition varies subtly but reproducibly with cellular effects such as progression through the cell cycle, cell maturation and differentiation, and disease. The aim of this summary is to provide a synopsis of the progress achieved in infrared spectral cytopathology (SCP) – the combination of infrared micro-spectroscopy and multivariate methods of analysis – for the detection of abnormalities in exfoliated human cells of the upper respiratory and digestive tract, namely the oral and nasopharyngeal cavities, and the esophagus.

Graphical abstract: Cancer screening via infrared spectral cytopathology (SCP): results for the upper respiratory and digestive tracts

Article information

Article type
Minireview
Submitted
26 Ago 2015
Accepted
24 Sep 2015
First published
28 Sep 2015

Analyst, 2016,141, 416-428

Cancer screening via infrared spectral cytopathology (SCP): results for the upper respiratory and digestive tracts

M. Diem, M. Miljković, B. Bird, A. I. Mazur, J. M. Schubert, D. Townsend, N. Laver, M. Almond and O. Old, Analyst, 2016, 141, 416 DOI: 10.1039/C5AN01751C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements