Issue 89, 2014

Enantioselective hydroacylation of olefins with rhodium catalysts

Abstract

Over thirty years ago, James and Young reported the first enantioselective olefin hydroacylation by using rhodium catalysts. This viewpoint highlights the advances in this area, including 4-pentenal cyclisations, medium-ring syntheses, and intermolecular variants.

Graphical abstract: Enantioselective hydroacylation of olefins with rhodium catalysts

  • This article is part of the themed collection: Viewpoints

Article information

Article type
Viewpoint
Submitted
27 Mac 2014
Accepted
23 Sep 2014
First published
03 Okt 2014

Chem. Commun., 2014,50, 13645-13649

Enantioselective hydroacylation of olefins with rhodium catalysts

S. K. Murphy and V. M. Dong, Chem. Commun., 2014, 50, 13645 DOI: 10.1039/C4CC02276A

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