Issue 23, 2013

Glucose selective Surface Plasmon Resonance-based bis-boronic acid sensor

Abstract

Saccharides – a versatile class of biologically important molecules – are involved in a variety of physiological and pathological processes, but their detection and quantification is challenging. Herein, surface plasmon resonance and self-assembled monolayers on gold generated from bis-boronic acid bearing a thioctic acid moiety, whose intramolecular distance between the boronic acid moieties is well defined, are shown to detect D-glucose with high selectivity, demonstrating a higher affinity than other saccharides probed, namely D-galactose, D-fructose and D-mannose.

Graphical abstract: Glucose selective Surface Plasmon Resonance-based bis-boronic acid sensor

Supplementary files

Article information

Article type
Paper
Submitted
29 Apr 2013
Accepted
18 Sep 2013
First published
22 Okt 2013
This article is Open Access
Creative Commons BY license

Analyst, 2013,138, 7140-7145

Glucose selective Surface Plasmon Resonance-based bis-boronic acid sensor

A. Stephenson-Brown, H. Wang, P. Iqbal, J. A. Preece, Y. Long, J. S. Fossey, T. D. James and P. M. Mendes, Analyst, 2013, 138, 7140 DOI: 10.1039/C3AN01233F

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