Self-degradable photosensitizer exhibiting bacterial agglutination and membrane insertion toward safe photodynamic ablation

Chengcheng Zhou; Yimei Li; Yihui Shen; Ze Lv; Jianguo Feng; Meijuan Jiang; Jian Du; Weijiang Guan

doi:10.1039/D4CC02264E

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Self-degradable photosensitizer exhibiting bacterial agglutination and membrane insertion toward safe photodynamic ablation†

Chengcheng Zhou,

*^a Yimei Li,^a Yihui Shen,^a Ze Lv,^b Jianguo Feng,

^b Meijuan Jiang,

^c Jian Du^d and Weijiang Guan

*^e

Author affiliations

* Corresponding authors

^a School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China
E-mail: zhoucc@yzu.edu.cn

^b College of Plant Protection, Yangzhou University, Yangzhou 225009, China

^c Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China

^d Department of Urology, The First Affiliated Hospital of Shandong First Medical University, No. 16766, Jingshi Road, Jinan 250000, China

^e State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, China
E-mail: wjguan@mail.buct.edu.cn

Abstract

Self-oxidative degradation photosensitizers capable of bacterial agglutination and membrane insertion were fabricated based on a simple co-assembly strategy, for efficiently killing P. aeruginosa and rapidly deactivating their function post-treatment.

This article is part of the themed collection: 2024 Emerging Investigators

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Article information

DOI: https://doi.org/10.1039/D4CC02264E
Article type: Communication
Submitted: 09 Mei 2024
Accepted: 07 Jun 2024
First published: 10 Jun 2024

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Chem. Commun., 2024,60, 7053-7056

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Self-degradable photosensitizer exhibiting bacterial agglutination and membrane insertion toward safe photodynamic ablation

C. Zhou, Y. Li, Y. Shen, Z. Lv, J. Feng, M. Jiang, J. Du and W. Guan, Chem. Commun., 2024, 60, 7053 DOI: 10.1039/D4CC02264E

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Chemical Communications

Self-degradable photosensitizer exhibiting bacterial agglutination and membrane insertion toward safe photodynamic ablation†

Abstract

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Self-degradable photosensitizer exhibiting bacterial agglutination and membrane insertion toward safe photodynamic ablation

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