Issue 3, 2022

Cu-mediated vs. Cu-free selective borylation of aryl alkyl sulfones

Abstract

A Cu-catalysed borylation of aryl alkyl sulfones was developed for the high yield synthesis of versatile arylboronic esters using a readily prepared NHC–Cu catalyst. In addition, the selective cleavage of either alkyl(C)–sulfonyl or aryl(C)–sulfonyl bonds of a cyclic sulfone via Cu-free or Cu-mediated processes generates the corresponding sulfinate salts, which can be further derivatised to provide sulfonyl-containing boronate esters, such as sulfones and sulfonyl fluorides.

Graphical abstract: Cu-mediated vs. Cu-free selective borylation of aryl alkyl sulfones

Supplementary files

Article information

Article type
Communication
Submitted
31 Okt 2021
Accepted
03 Des 2021
First published
03 Des 2021

Chem. Commun., 2022,58, 395-398

Cu-mediated vs. Cu-free selective borylation of aryl alkyl sulfones

M. Huang, M. Tang, J. Hu, S. A. Westcott, U. Radius and T. B. Marder, Chem. Commun., 2022, 58, 395 DOI: 10.1039/D1CC06144E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements