A series of new 2-phenyl-6-pyridinyl-2H-pyrazolo[4,3-c]pyridines was prepared. The most active compound 7f disrupts the microtubule cytoskeleton, alters cell morphology, causes mitotic defects, and ultimately leads to cell death.
In this study, we prepared a series of new N-(aminocycloalkylene)amino acid derivatives for use in chiral building blocks.
A synthesis of pyrrolo[2,1-a]isoquinolines based on intramolecular condensation of an enaminone intermediate obtained by C-acylation of an N-alkylated 6,7-dimethoxy-1-methyl-3,4-dihydroisoquinolinium salt was developed.
This study presents a battery-free wireless temperature sensor using HZO morphotropic phase boundary dielectric changes and passive LC resonance for signal transmission.
This review highlights the latest advancements in the meta-C–H functionalization of pyridines through a temporary dearomatization strategy involving dihydropyridine, oxazino-pyridine, Zincke imine and radical ion dearomatized intermediates.