New design and synthetic strategies were developed to generate functional phenyl boronic acid-based fluorescent probes with a 1,8-naphthylimide bright core, and their beta-D-glucan hybrids. These were monitored by MP FLIM for their ability to report changes in their environments in live cells.
A schematic overview of the FL probe HD-ALP designed for dynamic tracking of ALP activity in the different ovarian cells and models.
Our study introduces novel symmetrical and asymmetrical dihydropyridines as breast cancer inhibitors, showing cytotoxicity against MCF-7 cells and EGFR kinase inhibition. Molecular docking and dynamics validate superior binding to Lapatinib.
A one-pot in situ oxidation strategy was developed to construct a pyrazine-linked conjugated microporous polymer at the gram scale for high-performance proton conduction.
In this study, we developed a mitochondria-targeted near-infrared fluorescent probe HD-Br-D for simultaneous detection of H2S, Cys, and GSH in vitro and in vivo.