2D and layered materials for bio-integrated devices: insights into their multiscale interaction with biological moieties

Nabila Yasmeen, Nada Morsy, Mariam Badawi, Roberta Gagliani, Sung Mun Lee, Emmanuel Stratakis, Lucia Gemma Delogu, Yarjan Samad and Anna-Maria Pappa

J. Mater. Chem. C, 2025, 13, 19927
DOI: 10.1039/D5TC01114K

MXene/biomacromolecule composites: structures, properties, fabrication and applications

Chunbao Du, Mengyao Bai, Changji Yin, Shuquan Chen, Xiaoling Hu, Gang Zhang, Liang Cheng and Yuan Cheng

Nanoscale, 2026
DOI: 10.1039/D5NR05039A

Optoelectronic MXene quantum dots: frontiers in sensor technology for next-generation diagnostics and environmental monitoring

Ankur Singh, Supratim Mahapatra, Rajendra Prasad, Sumit Kumar Singh and Pranjal Chandra

Nanoscale, 2025, 17, 15554
DOI: 10.1039/D5NR00854A

miRNA electrochemical biosensors based on MXene and MBene nanomaterials: recent advances and future perspectives

Ameneh Taghavi-Kahagh, Farid Behboodi-Sadabad and Mehdi Salami-Kalajahi

J. Mater. Chem. B, 2025, 13, 7226
DOI: 10.1039/D5TB00472A

Strategies to enhance the supercapacitance performance of 2D MXenes through defect engineering, doping, hybridization, and magnetic field assistance: recent progress and challenges

Dhilip kumar Chinnalagu, Sathya Arumugam Thirumalai, Surjit Sahoo and Brahmananda Chakraborty

J. Mater. Chem. A, 2026
DOI: 10.1039/D6TA00255B

Biomedical potentials of MXene-based self-powered wearable devices: the future of next-generation wearables

Yeganeh Mohammadi Shahandashti, Sepehr Larijani, Mahnaz Eskandari, Atefeh Zarepour, Arezoo Khosravi, Siavash Iravani and Ali Zarrabi

RSC Adv., 2025, 15, 33773
DOI: 10.1039/D5RA04611D

Engineered Ti3C2(O,Cl) MXenes with dual functionalization: a new Frontier in targeted head and neck squamous cell carcinoma and breast adenocarcinoma

Jhansi Chintakindi, Ganesh Panditrao Lahane, Arti Dhar and Afkham Mir

J. Mater. Chem. B, 2025, 13, 6329
DOI: 10.1039/D5TB00302D

Tailoring Ti3C2Tx MXene multilayers for biomaterial integration: synthesis, characterization, and cytotoxicity

Pasa Yaman and Bedri Onur Kucukyildirim

Materials Science and Engineering: B, 2026, 323, 118752
DOI: 10.1016/j.mseb.2025.118752

Guides for Developing Hundreds of Novel Chiral MXenes and MBenes Nanosheets/Quantum Dots for Next‐Generation Chiral Engineered Biomaterials Applications

Alireza Rafieerad and Ahmad Amiri

Adv Healthcare Materials, 2025, 14
DOI: 10.1002/adhm.202502422

Antimicrobial and Antiviral Activities, and Biocompatibility of Titanium Coated with Electron Beam-Irradiated α-Silver Tungstate Microcrystals

Sarah Raquel de Annunzio, Marcelo Assis, Paula Aboud Barbugli, Alice Santos Rosa, Thamara Kelcya Fonseca Oliveira, Tayane Alvites Nunes Quintão, Vivian Neuza dos Santos Ferreira, Thayane da Encarnação Sá-Guimarães, Giovanna Barbosa da Conceição, Débora Ferreira Barreto-Vieira, Rodolfo Debone Piazza, Rodrigo Fernando Costa Marques, Milene Dias Miranda, Elson Longo and Carlos Eduardo Vergani

ACS Omega, 2025
DOI: 10.1021/acsomega.5c07850

Advances in MXene-Polymer Composites for Cutting-edge Supercapacitor and EMI Shielding Applications

Santosh K. Tiwari, Madhusudhan M. Devadiga, Ankur Sood, Sumanta Sahoo and Iftikhar Hussain

Applied Energy, 2026, 412, 127659
DOI: 10.1016/j.apenergy.2026.127659

MXene-Based Electrochemical Biosensors: Advancing Detection Strategies for Biosensing (2020–2024)

Joydip Sengupta and Chaudhery Mustansar Hussain

Biosensors, 2025, 15, 127
DOI: 10.3390/bios15030127

MXene Nanomaterial Interfaces: Pioneering Neural Signal Recording for Brain–Computer Interfaces and Cognitive Therapy

Anila Mukhtiar, Nabisab Mujawar Mubarak and Mohamed Aly Saad Aly

Top Curr Chem (Z), 2026, 384
DOI: 10.1007/s41061-026-00549-9

Synthesis strategies, functionalization, and biomedical applications of MOF/MXene hybrid composites

Giang Thanh Tran, Thuy Thi Thanh Nguyen and Thuan Van Tran

Coordination Chemistry Reviews, 2025, 544, 217002
DOI: 10.1016/j.ccr.2025.217002

A natural polymer-functionalized MXene/ZIF-67 nanocomposite as a synergistic platform for enhanced in vitro cell migration and antibacterial performance

Kasinathan Kasirajan, Marimuthu Karunakaran, Swaminathan Usha, Nagaraj Ganeshwari, V. Raja Preethi and Hong Kyoon Choi

International Journal of Biological Macromolecules, 2025, 322, 146946
DOI: 10.1016/j.ijbiomac.2025.146946

MXene-driven electrochemical platforms for bisphenol A sensing: Surface group interactions and reaction mechanisms

Kumarasamy Jayakumar, Vignesh Veeramuthu and Jintae Lee

Journal of Environmental Chemical Engineering, 2026, 14, 120676
DOI: 10.1016/j.jece.2025.120676

Review: recent developments in 2D MXene-filled bioinspired composites for biomedical applications

Yuksel Akinay, Mehmet Topuz, Umit Gunes, Muhammet Enver Gokdemir and Tayfun Cetin

J Mater Sci, 2025, 60, 10670
DOI: 10.1007/s10853-025-11114-y

A comprehensive review on MXenes for various applications

Zeeshan Ajmal, Abdul Qadeer, Karanpal Singh, Abdullah Al Mahmud, Muhammad Nazim Lakhan, Hareesh Pradeep, Basharat Hussain, Abid Ullah, Humaira Rashid Khan, Essam H. Ibrahim, Onkar Jaywant Kewate, Jianglong Cui, P. Rosaiah, Bhargav Akkinepally, Iftikhar Hussain and Wang Shuhang

Applied Energy, 2025, 397, 126136
DOI: 10.1016/j.apenergy.2025.126136

Surface aging of Ti-based MXene attenuates mitochondrial toxicity via suppressed cellular uptake and reactivity

Rui Zhang, Xiaodi Li, Yujiao Liu, Xuan Mao, Yongyi Wei, Yu Wang, Xiaofei Zhou and Jianbo Jia

Environmental Pollution, 2026, 395, 127793
DOI: 10.1016/j.envpol.2026.127793

Review: 2D MXenes for biomedical applications—recent advances, challenges, and future perspectives

Sunil Kumar, Nitu Kumari, Christopher Alma Suranto and Syed Muhammad Zain Mehdi

J Mater Sci, 2025, 60, 18595
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Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

Liang Guo, Yingran Shen, Jiaoyu Yi, Juanjuan Li, Ziming Wang, Erji Gao, Siqiang Zheng, Zhe‐Sheng Chen and Bo Tao

Advanced Science, 2026
DOI: 10.1002/advs.202521174

MXene-bio composite coatings for advanced sustainable fire retardancy at surfaces and interfaces

Faezeh Ghorbanizamani and Hichem Moulahoum

J Coat Technol Res, 2026, 23, 21
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MXene‐Based Functional Platforms for Diabetes Prevention and Treatment

Zixuan Wang, Yuhua Wang, Haijun Zhang, Yumei Wang, Jingwen Liu and Xinghui Liu

Carbon Neutralization, 2026, 5
DOI: 10.1002/cnl2.70130

Meta-analyses of the evolution of MXene synthesis for bioengineering and artificial intelligence-driven applications

Leena Regi Saleth, Mehak Gupta, Gautam Sharma, Elika Verma and Sanjiv Dhingra

Commun Mater, 2025, 6
DOI: 10.1038/s43246-025-01007-7

MXene-biomacromolecule nanosystems as multifunctional platforms for drug delivery and wound healing: current challenges and future perspectives

Yogesh Sawant, Malhari Kokare, Dipali Salunkhe, Mahendra Mahajan, Meghanath Shete and Sopan Nangare

Inorganic Chemistry Communications, 2026, 188, 116575
DOI: 10.1016/j.inoche.2026.116575

MXene‐Based Electrochemiluminescence (ECL) Biosensors: A Review on Analyte Detection and Diagnostic Applications

Kai Zhang

MedComm – Biomaterials and Applications, 2025, 4
DOI: 10.1002/mba2.70027

Surface Engineering of MXenes for Biomedical Uses: Functionalization Strategies and Application Trends

Sehyeon Park, Hee Jeong Byun and Jae Young Lee

Biomater Res, 2026, 30
DOI: 10.34133/bmr.0327

MXene-cellulose composite for healthcare applications: synthesis, properties and future outlook

Mokae Bambo, Teboho Clement Mokhena and Joe Modise

Front. Sens., 2026, 7
DOI: 10.3389/fsens.2026.1757732

Scalable microwave-assisted production of Ti₃C₂Tx MXene for next-generation Li-ion and Na-ion batteries

P.E. Lokhande, Prashant Misal, Ramchandra S. Kalubarme, Milind V. Kulkarni, Udayabhaskar Rednam, Shailesh Padlkar and Bandar Ali Al-Asbahi

Diamond and Related Materials, 2025, 157, 112503
DOI: 10.1016/j.diamond.2025.112503

3D‐Printed Auxetic Hydrogel Dressings Reinforced With MXene and Carbonized Polymer Dots for Cascaded Antibacterial and Pro‐Regenerative Effects in Wound Healing

Chen‐Yu Lee, Ya‐Ting Hsu, Qian‐Ci Huang, Pulikkutty Subramaniyan, Akhil K. Paulose, Chih‐Ching Huang and Tzu‐En Lin

Small, 2026, 22
DOI: 10.1002/smll.202508633

Green-synthesized MXenes enable low-friction, cytocompatible PVA-chitosan hydrogels

Leonarda Vukonic, Marko Piljević, Markus Ostermann, Felix Groß, Christoph Bauer, Philipp J. Thurner, Oleksiy Gogotsi, Manel Rodríguez Ripoll and Carsten Gachot

International Journal of Biological Macromolecules, 2026, 352, 151144
DOI: 10.1016/j.ijbiomac.2026.151144

Ti 3 C 2 T x MXene/halloysite nanotube functionalized films for antibacterial applications

Mehmet Topuz, Erkan Karatas, Damla Ruzgar, Yuksel Akinay and Tayfun Cetin

Journal of Biomaterials Science, Polymer Edition, 2025, 36, 3185
DOI: 10.1080/09205063.2025.2522746

Apoptosis induction and anti-inflammatory cytokines effects of sorafenib-loaded MXene-UiO-66@liposome nanocomposites in liver cancer under NIR irradiation

Shehab Elbeltagi, Sahar Mansour, Hagar M. El-Tohamy, A.M. Ismail, Khaled M. Abdelbased, Mansour A. Alanazi, Nada S. Al-Theyab and Zienab E. Eldin

Diamond and Related Materials, 2026, 161, 113092
DOI: 10.1016/j.diamond.2025.113092