Investigation of the in vitro anticancer potential of bis(imino)acenaphthene–N-heterocyclic carbene transition metal complexes revealed TrxR inhibition and triggering of immunogenic cell death (ICD) for allyl palladates

Chiara Donati, Ishfaq Ibni Hashim, Nestor Bracho Pozsoni, Laurens Bourda, Kristof Van Hecke, Catherine S. J. Cazin, Fabiano Visentin, Steven P. Nolan, Valentina Gandin and Thomas Scattolin

RSC Med. Chem., 2025, 16, 2592
DOI: 10.1039/D5MD00039D

Cationic and homoleptic copper(i)–thiazol-2-ylidenes: highly reactive thiazole N-heterocyclic carbenes as σ-Lewis acid catalysts

Ruihong Wang, Jin Zhang, Hang Yang, Yawei Zhu, Yan Guo, Xiaoxia Han, Roman Szostak and Michal Szostak

Org. Chem. Front., 2025, 12, 6201
DOI: 10.1039/D5QO00772K

Trace amounts of palladium catalysed the Suzuki–Miyaura reaction of deactivated and hindered aryl chlorides

Zhenhua Li, Dayou Rong, Longfeng Yuan, Zhihong Zhao, Fenghao Dai, Lijun Chen and Yuanyuan Xie

Org. Biomol. Chem., 2024, 22, 4559
DOI: 10.1039/D4OB00623B

A well-defined Pd(ii)-NHC aqua complex for ambient Buchwald–Hartwig amination in tert-butanol

Yaxu Liu, Zheng Wang, Ziyi Quan, Fengze Sun, Lixing Zhao, Lei Guo, Yixuan Gao and Bo Wang

Green Chem., 2026, 28, 6842
DOI: 10.1039/D6GC00831C

A robust [Pd(BIAN-IPr#)Cl2(H2O)] catalyst employing water as a disposable ligand for C–S cross coupling of aryl chlorides and thiols

Ziyi Quan, Zheng Wang, Yaxu Liu, Yuanchao Sun and Bo Wang

Dalton Trans., 2026
DOI: 10.1039/D6DT00623J

Air-stable, well-defined palladium–BIAN–NHC chloro dimer: Highly efficient N-Heterocyclic carbene (NHC) catalyst platform for Buchwald–Hartwig C–N cross-coupling reactions

Jin Zhang, Jianglong Cai, Xue Li, Gaopeng Zhang, Wenxuan Yan, Renjie Li, Jianbo Tong and Michal Szostak

Journal of Catalysis, 2024, 439, 115783
DOI: 10.1016/j.jcat.2024.115783

A new air-stable Pd-PEPPSI N-heterocyclic carbene complex: Synthesis, structure, computational and catalytical studies

Bibekananda Gogoi, Sangeeta Khargharia, Rahul Kar, Biraj Jyoti Borah and Pankaj Das

Journal of Molecular Structure, 2024, 1295, 136678
DOI: 10.1016/j.molstruc.2023.136678

Site-Selective Copper–N-Heterocyclic Carbene-Catalyzed C(sp2)–C(sp) Cross-Coupling of Aryl Thianthrenium Salts

Jin Zhang, Hang Yang, Li Sun, Yan Guo, Gaopeng Zhang, Ruihong Wang and Michal Szostak

Org. Lett., 2025, 27, 3440
DOI: 10.1021/acs.orglett.5c00875

Pd-Catalyzed Azidation of Aryl (Pseudo)Halides

Shangyu Li, Polpum Onnuch and Richard Y. Liu

ACS Catal., 2025, 15, 17429
DOI: 10.1021/acscatal.5c05497

Base‐Ionizable Anionic NHC Ligands in Pd‐catalyzed Reactions of Aryl Chlorides

Andrey Yu. Chernenko, Victoria A. Baydikova, Vadim V. Kutyrev, Alexander V. Astakhov, Mikhail E. Minyaev, Victor M. Chernyshev and Valentine P. Ananikov

ChemCatChem, 2024, 16
DOI: 10.1002/cctc.202301471

Recent advances in PEPPSI–themed palladium NHC complexes: Applications ranging from homogeneous catalysis to electrocatalysis

Nalluchamy Muniyappan and Srinivasa Budagumpi

Inorganica Chimica Acta, 2026, 589, 122915
DOI: 10.1016/j.ica.2025.122915

[Pd(NHC)(μ-Cl)Cl]2: The Highly Reactive Air- and Moisture-Stable, Well-Defined Pd(II)-N-Heterocyclic Carbene (NHC) Complexes for Cross-Coupling Reactions

Shiyi Yang, Tongliang Zhou, Xiang Yu, Steven P. Nolan and Michal Szostak

Acc. Chem. Res., 2024, 57, 3343
DOI: 10.1021/acs.accounts.4c00549

Dinuclear Rhodium(I)–N‐Heterocyclic Carbene Complexes as Alkyne Hydropyridonation Catalysts

Belinda Español‐Sánchez, Mert Olgun Karataş, Andrea Di Giuseppe, Ulugbek Togaev, Vincenzo Passarelli, Luis A. Oro, Jesús J. Pérez‐Torrente and Ricardo Castarlenas

Eur J Inorg Chem, 2026, 29
DOI: 10.1002/ejic.202500598

Expanding the Role of Dimeric Species: On-Cycle Involvement, Improved Stability, and Control of Stereo-Specificity. A Case Study of Atom-Economic Catalytic Hydrothiolation

Liliya T. Sahharova, Julia V. Burykina, Alexander Yu. Kostyukovich, Dmitry B. Eremin, Daniil A. Boiko, Artem N. Fakhrutdinov and Valentine P. Ananikov

ACS Catal., 2023, 13, 3591
DOI: 10.1021/acscatal.2c06406

Metal–N-Heterocyclic Carbene Complexes in Buchwald–Hartwig Amination Reactions

Sourav Sekhar Bera, Greta Utecht-Jarzyńska, Shiyi Yang, Steven P. Nolan and Michal Szostak

Chem. Rev., 2025, 125, 5349
DOI: 10.1021/acs.chemrev.5c00088

Copper(I)–Thiazol-2-ylidenes: Highly Reactive N-Heterocyclic Carbenes for the Hydroboration of Terminal and Internal Alkynes. Ligand Development, Synthetic Utility, and Mechanistic Studies

Jin Zhang, Xue Li, Tao Li, Gaopeng Zhang, Kerou Wan, Yangmin Ma, Ran Fang, Roman Szostak and Michal Szostak

ACS Catal., 2022, 12, 15323
DOI: 10.1021/acscatal.2c04668

Advanced Pd–NAPA Precatalysts for Broad‐Scope Kumada–Tamao–Corriu Couplings of Challenging Aryl Chlorides

Pei‐Zhen Xie, Wan‐Qin Zeng, Yu‐Hsiang Liu, Yingjie Guo, Hsuan‐Hao Kang, Yung‐De Tsai, Yi‐Jie Tsai, Li‐Hui Hong, Yun‐Rou Zeng, Yen‐Hsien Li, Wei‐Chih Chen, I‐Chung Lu and Yu‐Chang Chang

Asian J Org Chem, 2025, 14
DOI: 10.1002/ajoc.202500332

NHC/Phosphite Nickel(II) Precatalysts for the C–N Cross-Coupling of (Hetero)Aryl Chlorides under Mild Conditions

Nutan R. Darandale, Morgan E. John, Stephen A. Moggach, Dinesh N. Sawant, George A. Koutsantonis, Reto Dorta and Scott G. Stewart

Org. Lett., 2025, 27, 10526
DOI: 10.1021/acs.orglett.5c03230

Pd(II)–NHC (NHC = N‐Heterocyclic Carbene)‐Catalyzed Alkylation of Primary Amides by Site‐Selective N─C(O) Activation

Peng Lei, Yuge Hu, Deshuang Zhang, Jiuhui Ye, Yanqing Gao, Juntao Feng, Zhiqing Ma, Xili Liu and Michal Szostak

Advanced Science, 2025, 12
DOI: 10.1002/advs.202511827