Issue 31, 2024

Advances in biomimetic AIE nanoparticles for diagnosis and phototherapy

Abstract

This minireview provides an overview of the recent advancements in the development of biomimetic Aggregation-Induced Emission (AIE) nanoparticles and their applications in disease diagnosis, phototherapy, and photoimmunotherapy. AIE nanoparticles can be engineered to enable efficient image-guided photodynamic and photothermal therapies, however, challenges related to immune defense and target specificity persist. To overcome these, coating biomimetic materials on the surface of AIE nanoparticles, which mimic the features and functions of native cells, have emerged as a promising solution. This minireview will highlight the synthesis strategies and discuss the biomedical application of biomimetic AIE nanoparticles.

Graphical abstract: Advances in biomimetic AIE nanoparticles for diagnosis and phototherapy

Article information

Article type
Minireview
Submitted
31 mar 2024
Accepted
11 jul 2024
First published
15 jul 2024
This article is Open Access
Creative Commons BY-NC license

Nanoscale, 2024,16, 14707-14715

Advances in biomimetic AIE nanoparticles for diagnosis and phototherapy

J. H. C. Chau, M. M. S. Lee, E. Y. Yu, R. T. K. Kwok, J. W. Y. Lam, J. Sun and B. Z. Tang, Nanoscale, 2024, 16, 14707 DOI: 10.1039/D4NR01417K

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