Issue 36, 2023

Tetralactam macrocycle based indicator displacement assay for colorimetric and fluorometric dual-mode detection of urinary uric acid

Abstract

An indicator displacement assay for colorimetric and fluorometric dual-mode detection of urinary uric acid (UA) was constructed using a water-soluble naphthalene-based tetralactam macrocycle and the phenoxazine dye, resorufin (RF). The visual detection of UA levels of volunteers was successfully realized using modified paper assays, which could be used for the home monitoring of urinary UA.

Graphical abstract: Tetralactam macrocycle based indicator displacement assay for colorimetric and fluorometric dual-mode detection of urinary uric acid

Supplementary files

Article information

Article type
Communication
Submitted
05 dec 2022
Accepted
29 mar 2023
First published
29 mar 2023

Chem. Commun., 2023,59, 5411-5414

Tetralactam macrocycle based indicator displacement assay for colorimetric and fluorometric dual-mode detection of urinary uric acid

H. Yao, S. Li, H. Zhang, X. Pang, J. Lu, C. Chen, W. Jiang, L. Yang and L. Wang, Chem. Commun., 2023, 59, 5411 DOI: 10.1039/D2CC06622J

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