Issue 7, 2018

Mobile diagnostics: next-generation technologies for in vitro diagnostics

Abstract

The emergence of a wide range of applications of smartphones along with advances in ‘liquid biopsy’ has significantly propelled medical research particularly in the field of in vitro diagnostics (IVD). Herein, we have presented a detailed analysis of IVD, its associated critical concerns and probable solutions. It also demonstrates the transition in terms of analytes from minimally invasive (blood) to non-invasive (urine, saliva and sweat) and depicts how the different features of a smartphone can be integrated for specific diagnostic purposes. This review basically highlights recent advances in the applications of smartphone-based biosensors in IVD taking into account the following factors: accuracy and portability; quantitative and qualitative analysis; and centralization and decentralization tests. Furthermore, the critical concerns and future direction of diagnostics based on smartphones are also discussed.

Graphical abstract: Mobile diagnostics: next-generation technologies for in vitro diagnostics

Article information

Article type
Minireview
Submitted
01 dec 2017
Accepted
10 feb 2018
First published
13 feb 2018

Analyst, 2018,143, 1515-1525

Mobile diagnostics: next-generation technologies for in vitro diagnostics

J. Shin, S. Chakravarty, W. Choi, K. Lee, D. Han, H. Hwang, J. Choi and H. Jung, Analyst, 2018, 143, 1515 DOI: 10.1039/C7AN01945A

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