Advances in crosslinking strategies of biomedical hydrogels
This review presents the commonly used crosslinking methods for hydrogel synthesis and summarizes the current status and discusses future perspectives.
Rational design and latest advances of polysaccharide-based hydrogels for wound healing
This review presented the crucial design considerations and current state of polysaccharide-based hydrogels as wound dressings. The commonly used crosslinking techniques are also discussed in detail.
Strategies for transporting nanoparticles across the blood–brain barrier
Nanoparticles have been widely deployed for brain-targeted delivery. Drugs can be embedded either in a matrix or deposited on the surface of nanoparticles, and the whole particle can cross the BBB effectively and be targeted to specific parts of the body in a controllable manner.
3D printed gelatin/hydroxyapatite scaffolds for stem cell chondrogenic differentiation and articular cartilage repair
The hUCB-MSC-laden 3D printed gelatin/HAP scaffold effectively repairs knee cartilage defects in a pig model.
Antibacterial and hydroxyapatite-forming coating for biomedical implants based on polypeptide-functionalized titania nanospikes
The immobilization of mussel-inspired polypeptide onto biomimetic titania nanospike coating enhanced its antibacterial ability and bioactivity, thus holding great promise for utilization for orthopedic and dental implants.
Doxorubicin-loaded nanoscale metal–organic framework for tumor-targeting combined chemotherapy and chemodynamic therapy
DMH NPs were prepared and could effectively induce MCF-7 cell death through the combination of chemotherapy and chemodynamic therapy.
Tannic acid-loaded mesoporous silica for rapid hemostasis and antibacterial activity
The as-prepared tannic acid (TA)-load mesoporous silica via electrostatic adsorption (TMS) exhibited excellent hemorrhage control by both TA-induced faster blood contact and plasma protein crosslinking, and MS-initiated water absorption, blood components concentration and coagulation factors activation, and good antibacterial properties.
Noninvasive rapid bacteria-killing and acceleration of wound healing through photothermal/photodynamic/copper ion synergistic action of a hybrid hydrogel
Bacterial infection often delays healing of wounded tissues and so it is essential to improve the antibacterial efficiency in situ.
Tuning protein assembly pathways through superfast amyloid-like aggregation
Three structural elements for protein assembly are proposed, which guide superfast amyloid-like globular protein aggregation towards macroscopic nanofilms and microparticles.
Simultaneous detection of multiple viruses based on chemiluminescence and magnetic separation
In this report, a DNA hybridization based chemiluminescent detection method has been proposed for reliable detection of multiple pathogens. The use of surface modified magnetic nanoparticles can help to integrate this system into an automated platform for high throughput applications.
Preparation of pH-responsive mesoporous hydroxyapatite nanoparticles for intracellular controlled release of an anticancer drug
A well-defined core–shell nano-carrier (PAA–MHAPNs) was successfully synthesized based on a graft-onto method by using mesoporous hydroxyapatite nanoparticles (MHAPNs) as the core and polyacrylic acid (PAA) as the shell.
A combination of tri-modal cancer imaging and in vivo drug delivery by metal–organic framework based composite nanoparticles
A facile method was developed for the synthesis of multifunctional Fe3O4@PAA/AuNCs/ZIF-8 NPs. Furthermore, the obtained NPs with ultrahigh drug storage capacity and dual pH-responsive drug release properties were applicable in simultaneous tri-modal.
Graphene film doped with silver nanoparticles: self-assembly formation, structural characterizations, antibacterial ability, and biocompatibility
Reduced graphene oxide film decorated with silver nanoparticles shows enhanced antibacterial activity and improved biocompatibility.
Biologically inspired membrane design with a heparin-like interface: prolonged blood coagulation, inhibited complement activation, and bio-artificial liver related cell proliferation
A blood-contact membrane with a heparin-like interface was designed with prolonged blood coagulation, inhibited complement activation and excellent liver cell proliferation.
Study on effective extraction of chicken feather keratins and their films for controlling drug release
Keratin was extracted from chicken feathers, and applied to prepare keratin films which were pH-responsive and showed controllable drug-release behavior.
About this collection
This online collection features some of the most cited, most downloaded and most shared articles from China published in Biomaterials Science during the first 10 years of the journal.
Congratulations to all the authors whose articles are featured and thank you to all our authors, reviewers and readers for your ongoing support.