Nanozymes in cancer immunotherapy: metabolic disruption and therapeutic synergy

Xiangrui Xu, Yaowen Zhang, Chijun Meng, Wenzhuo Zheng, Lingfeng Wang, Chenyi Zhao and Feng Luo

J. Mater. Chem. B, 2024, 12, 9111
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A comprehensive exploration of the latest innovations for advancements in enhancing selectivity of nanozymes for theranostic nanoplatforms

Dan Li, Tuocen Fan and Xifan Mei

Nanoscale, 2023, 15, 15885
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Prudently designed Se@fMWCNT as a peroxidase mimicking nanozyme for distinctive electrochemical detection of H2O2 and glutathione

Vadakke Purakkal Sruthi and Sellappan Senthilkumar

J. Mater. Chem. C, 2024, 12, 8924
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An oxidized chondroitin sulfate-crosslinked and CuCDs-loaded decellularized bovine pericardium with improved anti-coagulation, pro-endothelialization and anti-calcification properties for BHVs

Shubin Shi, Xu Wei, Xu Peng, Xinyun Pu, Shaoxiong Feng, Xi Gao and Xixun Yu

J. Mater. Chem. B, 2025, 13, 7196
DOI: 10.1039/D5TB00827A

Rational Design of Nanozymes for Engineered Cascade Catalytic Cancer Therapy

Xiuna Jia, Erkang Wang and Jin Wang

Chem. Rev., 2025, 125, 2908
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Nanozyme-based cancer theranostics: A scientometric analysis and comprehensive review

Yang Xing, Feroza Yasinjan, Shuhao Sun, Jiaying Yang, Yajie Du, Haotian Zhang, Yueyang Liang, Huayue Geng, Yingtong Wang, Jicheng Sun, Zihang Yu, Dhan V. Kalvakolanu, Wei Jiang, Ling Zhang, Kelong Fan and Baofeng Guo

Nano Today, 2024, 57, 102386
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Metal-free multifunctional nanozymes mimicking endogenous antioxidant system for acute kidney injury alleviation

Jiawei Liu, Xinyu Huang, Fengxian Zhang, Xueting Luo, Wenqian Yu, Cao Li, Zhenpeng Qiu, Yi Liu and Ziqiang Xu

Chemical Engineering Journal, 2023, 477, 147048
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Optical activity invertible chiral WSe2 quantum dots as intracellular redox state indicator and regulator

Haimei Yang, Zixuan Ding, Jiayin Du, Xianlin He and Jianan Huang

Chemical Engineering Journal, 2024, 485, 149839
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Advances in metal-organic framework-based nanozymes in ROS scavenging medicine

Zhong Xu, Liang Chen, Yan Luo, Yan-Mei Wei, Ning-Yuan Wu, Lan-Fang Luo, Yong-Biao Wei and Jin Huang

Nanotechnology, 2024, 35, 362006
DOI: 10.1088/1361-6528/ad572a

Nanozymes - A new opportunity for the treatment of neurodegenerative diseases

Yiqi Zhou, Xuan Zhou, Yanyan Song, Qi Tian, Shanhe Li, Tingting Li and Xiufang Lu

Chemical Engineering Journal, 2025, 525, 169965
DOI: 10.1016/j.cej.2025.169965

Tellurium‐Containing Crown Ether Nanozyme with Robust Redox Adaptability and Potent Glutathione Peroxidase‐Like Activity

Bo Li, Yujie Li, Xin Shen, Yan Ge and Zhenhui Qi

ChemistrySelect, 2025, 10
DOI: 10.1002/slct.202405879

Recent Applications of Melanin-like Nanoparticles as Antioxidant Agents

Alexandra Mavridi-Printezi, Arianna Menichetti, Dario Mordini, Riccardo Amorati and Marco Montalti

Antioxidants, 2023, 12, 863
DOI: 10.3390/antiox12040863

BioHJzyme-Armed Hydrogel for Infectious Wound Monitoring Through Enzyme-Mimetic Antibacterial Activities and Macrophage Regulation

Zuyao Wang, Miaomiao He, Xinyan Pang, Guangfu Yin, Yi Deng and Weizhong Yang

Chemical Engineering Journal, 2024, 488, 151005
DOI: 10.1016/j.cej.2024.151005

TME-Activated MnO2/Pt Nanoplatform of Hydroxyl Radical and Oxygen Generation to Synergistically Promote Radiotherapy and MR Imaging of Glioblastoma

Lijuan Chen, Mingbo Liu, Yunjuan Wang, Wei Wei, Yaqiong Li, Yan Bai, Xuan Yu, Lei Jiao and Meiyun Wang

IJN, 2024, Volume 19, 11055
DOI: 10.2147/IJN.S474098

The biomedical applications of nanozymes in orthopaedics based on regulating reactive oxygen species

Xiangcheng Gao, Jiejie Zhang, Yining Gong and Liang Yan

J Nanobiotechnol, 2024, 22
DOI: 10.1186/s12951-024-02844-3

Oxidative stress products and managements in atopic dermatitis

Yingqiang Luo, Jun Hu, Zihao Zhou, Yan Zhang, Yaguang Wu and Jiaying Sun

Front. Med., 2025, 12
DOI: 10.3389/fmed.2025.1538194

Pathogenesis guided application of nanozymes in the treatment of inflammatory bowel disease

Fang Lei, Qizhen Huang, Chengfeng Zhang, Youhui Lin, Yan Zhang and Faming Wang

Materials Today Bio, 2025, 33, 102008
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Enzyme-mimetic antioxidant nanomaterials for ROS scavenging: Design, classification, and biological applications

Shuwen Zhou, Huijuan Cai, Xinjuan He, Zhiyong Tang and Siyu Lu

Coordination Chemistry Reviews, 2024, 500, 215536
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A Glutathione Peroxidase‐Mimicking Nanozyme Precisely Alleviates Reactive Oxygen Species and Promotes Periodontal Bone Regeneration

Bijun Zhu, Jiangjiexing Wu, Tong Li, Songtao Liu, Junheng Guo, Yijun Yu, Xinyi Qiu, Yue Zhao, Haoran Peng, Jinli Zhang, Leiying Miao and Hui Wei

Adv Healthcare Materials, 2024, 13
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Mito-Nanozyme: Mitochondria-Targeted Nanozyme for Cancer Therapy

Zongjun Li, Jie Song, Xiaoqing Zhao, Keyan Wang, Yueyang Liang, Ling Zhang, Baofeng Guo and Wei Jiang

Coordination Chemistry Reviews, 2025, 542, 216899
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Synergistic antimicrobial Cur-PEI-Mn3O4 for wound sterilization and accelerated healing

Yinyin Chen, Nana Liu, Qiuju Wu, Wei Wu, Wei Fan, Aimin Wu and Xianxiang Wang

Materials Today Chemistry, 2025, 50, 103163
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L‐Arginine‐Modified Selenium Nanozymes Targeting M1 Macrophages for Oral Treatment of Ulcerative Colitis

Shuaiwen Li, Zihui Chen, Minyu Wang, Yao Rao, Feng Yang, Mei Liu, Weihua Chu and Wanqing Yue

Small, 2025, 21
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Nanozyme-Based Remodeling of Disease Microenvironments for Disease Prevention and Treatment: A Review

Yikun Ju, Xiangjun Liu, Xiuzhi Ye, Minghai Dai, Bairong Fang, Xinkun Shen and Liangle Liu

ACS Appl. Nano Mater., 2023, 6, 13792
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Geroprotective effects of GdVO4:Eu3 + nanoparticles, metformin and calorie restriction in male rats with accelerated aging induced by overnutrition in early postnatal ontogenesis

Yuri V. Nikitchenko, Vladimir K. Klochkov, Nataliya S. Kavok, Nina A. Karpenko, Svetlana L. Yefimova, Vladimir P. Semynozhenko, Irina V. Nikitchenko and Anatoly I. Bozhkov

Biogerontology, 2025, 26
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Enhanced peroxidase‐like activity of MnFe2O4 nanoparticles on halloysite nanotubes for uric acid detection

Hengxia Shen, Zhenbo Xiang and Anfang Dang

Asia-Pacific J Chem Eng, 2025, 20
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Engineered metallic hybrid nanozyme for advanced inflammatory disease therapy

Xueqian Xia, Xiang Liu, Yue Gao, Jiatong Lin, Shuangxue Pan, Weijian Cheng, Sheng Huang, Xingyue Liu, Jia-Wei Shen and Wei Duan

Materials Today Bio, 2025, 35, 102572
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Recent trends in nanozyme research and their potential therapeutic applications

Aparajita Sen, Jyoti Oswalia, Sneha Yadav, Meenakshi Vachher and Arti Nigam

Current Research in Biotechnology, 2024, 7, 100205
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The Paradigm of Safe and Sustainable‐by‐Design Synthetic Catalysts for Catalytic Therapies

Esteban Zingales, Claudia Miranda‐Pérez de Alejo, Manu Sánchez, Laura Fernández‐Méndez, Jesús Ruíz‐Cabello, Carlos Sanchez‐Cano and Susana Carregal‐Romero

ChemCatChem, 2025, 17
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Nanozymes Integrated Biochips Toward Smart Detection System

Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong and Lingqian Chang

Advanced Science, 2025
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Deep Insight of Design, Mechanism, and Cancer Theranostic Strategy of Nanozymes

Lu Yang, Shuming Dong, Shili Gai, Dan Yang, He Ding, Lili Feng, Guixin Yang, Ziaur Rehman and Piaoping Yang

Nano-Micro Lett., 2024, 16
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Recent Advancements in the Formulation of Nanomaterials-Based Nanozymes, Their Catalytic Activity, and Biomedical Applications

Swati Singh, Nilesh Rai, Harshita Tiwari, Priyamvada Gupta, Ashish Verma, Rajiv Kumar, Vikas Kailashiya, Prafull Salvi and Vibhav Gautam

ACS Appl. Bio Mater., 2023, 6, 3577
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Advances in design and preparation of nanozymes and their applications for constructing higher sensitive lateral flow assays

Haiyin Li, Yue Peng, Xinda Huang, Rongyan Wan, Li Zhang, Xuan Wang, Lirong Han, Linsen Li, Chuanfeng Wang and Jianling Chen

Coordination Chemistry Reviews, 2024, 510, 215797
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Ultrasmall Cu2O@His Nanozymes with RONS Scavenging Capability for Anti-inflammatory Therapy

Shuaiwen Li, Zihui Chen, Minyu Wang, Feng Yang, Shuqi Zhang, Cairong Qiao, Weihua Chu and Wanqing Yue

ACS Appl. Mater. Interfaces, 2024, 16, 3116
DOI: 10.1021/acsami.3c15083

Efficient hydrogen peroxide reduction in glutathione peroxidase cycle using cost-effective FeSe2 nanospheres

Saif Khan, Sundeep S. Bhagwath, Mohammad Rehan Ajmal, Intikhab A. Ansari, Mohtashim Lohani, Sanjaya Pavgada Raghunandana and Mohammad Luqman

Front. Agron., 2025, 6
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Graphene quantum dot/hydrogel nanozyme composites: a next-generation approach for point-of-care diagnostics and non-destructive biomedical evaluation

Seyyed Mojtaba Mousavi, Masoomeh Yari Kalashgrani, Ahmad Gholami, Muhammad Fazle Rabbee, Vahid Rahmanian, Fatemeh Fallahi Nezhad, Mahmood D. Aljabri, Mohammed Muzibur Rahman and Wei-Hung Chiang

Microchemical Journal, 2025, 216, 114690
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Nanozyme-based therapies for inflammatory immune disorders: opportunities and challenges

Wenqian Zhang, Shaozhe Cai, Jiayi Ma, Rongfen Gao and Lingli Dong

Inflamm. Res., 2026, 75
DOI: 10.1007/s00011-025-02175-5

Nanozymes for the Therapeutic Treatment of Diabetic Foot Ulcers

Xueqian Xiao, Fei Zhao, Davida Briana DuBois, Qiming Liu, Yu Lin Zhang, Qunfeng Yao, Guo-Jun Zhang and Shaowei Chen

ACS Biomater. Sci. Eng., 2024, 10, 4195
DOI: 10.1021/acsbiomaterials.4c00470