A review on Stimuli-pH responsive liposomal formulation in cancer therapy

P. Jayapriya, Ekta Pardhi, Ravindra Vasave, Santosh Kumar Guru, Jitender Madan and Neelesh Kumar Mehra

Journal of Drug Delivery Science and Technology, 2023, 90, 105172
DOI: 10.1016/j.jddst.2023.105172

Targeting Hypoxia-Inducible Factor-1 (HIF-1) in Cancer: Emerging Therapeutic Strategies and Pathway Regulation

Reem A. Qannita, Ayah I. Alalami, Amani A. Harb, Shereen M. Aleidi, Jalal Taneera, Eman Abu-Gharbieh, Waseem El-Huneidi, Mohamed A. Saleh, Karem H. Alzoubi, Mohammad H. Semreen, Mohammad Hudaib and Yasser Bustanji

Pharmaceuticals, 2024, 17, 195
DOI: 10.3390/ph17020195

Regulation of the intermittent release of giant unilamellar vesicles under osmotic pressure

Qi Zhou, Ping Wang, Bei-Bei Ma, Zhong-Ying Jiang and Tao Zhu

Chinese Phys. B, 2022, 31, 098701
DOI: 10.1088/1674-1056/ac4a69

Echinomycin: A Journey of Challenges

Zainab Lafi, Walhan Alshaer, Ma’mon M. Hatmal, Malek A. Zihlif, Nisreen Y. Asha, Hiba Abdelnabi and Abdullah Awidi

Jordan j. pharm. sci., 2023, 16, 640
DOI: 10.35516/jjps.v16i3.918

Co-encapsulation of coumarin and Q10 into solid lipid nanoparticles for wound healing

Maisrh Ali Alrubaye, Zainab Lafi, Maha N. Abu Hajleh, Tamer M.M. Abuamara and Afnan Mehdawi

Journal of Drug Delivery Science and Technology, 2025, 105, 106645
DOI: 10.1016/j.jddst.2025.106645

A Recent Review of PLGA-PEG Hybrid Nanoparticles for Anticancer and Anti-Inflammatory Applications

Sina Matalqah, Zainab Lafi and Aya Y. Al-Kabariti

Jordan j. pharm. sci., 2025, 18, 180
DOI: 10.35516/jjps.v18i1.2737

Preparation, Characterization, and Anticancer Activity of PEGylated Nano Liposomal Loaded with Rutin against Human Carcinoma Cells (HT‐29)

Noorin Manhal Al‐Ekaid, Ali Al‐Samydai, Ibrahim Al‐deeb, Hamdi Nsairat, Khaled Khleifat and Walhan Alshaer

Chemistry & Biodiversity, 2023, 20
DOI: 10.1002/cbdv.202301167

DOPE/CHEMS-Based EGFR-Targeted Immunoliposomes for Docetaxel Delivery: Formulation Development, Physicochemical Characterization and Biological Evaluation on Prostate Cancer Cells

Thais da Silva Moreira, Alan Denis Olivindo Silva, Bianca Rodrigues Farias Vasconcelos, Elias da Silva Santos, Ana Carolina Cruz de Sousa, João Vito Barroso de Freitas, Yara Santiago de Oliveira, Laura Maria Teodorio Vidal, Fábio de Oliveira Silva Ribeiro, Alyne Rodrigues de Araújo, José de Brito Vieira Neto, Cláudia do Ó Pessoa, Raquel Petrilli and Josimar O. Eloy

Pharmaceutics, 2023, 15, 915
DOI: 10.3390/pharmaceutics15030915

Preparation, Optimization and In vitro Evaluation of Doxorubicin‐loaded into Hyaluronic Acid Coated Niosomes Against Breast Cancer

Haya Faddah, Hamdi Nsairat, Naeem M. Shalan, Mohamed El‐Tanani, Dana A. Alqudah and Walhan Alshaer

Chemistry & Biodiversity, 2024, 21
DOI: 10.1002/cbdv.202301470

Aptasensors: Employing Molecular Probes for Precise Medical Diagnostics and Drug Monitoring

Zainab Lafi, Lobna Gharaibeh, Hamdi Nsairat, Nisreen Asha and Walhan Alshaer

Bioanalysis, 2023, 15, 1439
DOI: 10.4155/bio-2023-0141

Curcumin-loaded γ -cyclodextrin-grafted hyaluronic acid nanoassimblies: In vitro investigation of anti-proliferative, wound healing, and anti-inflammatory potential

Fedaa Adaileh, Walhan Alshaer, Hamdi Nsairat, Dana A. Alqudah, Suha Wehaibi, Fadwa Daoud, Rula Al-Buqain, Shrouq Alsotari, Abeer Al Bawab and Fadwa Odeh

Journal of Drug Delivery Science and Technology, 2023, 87, 104886
DOI: 10.1016/j.jddst.2023.104886

Impact of hydroxyapatite nanoparticles on the cellular processes of stem cells derived from dental tissue sources

Mais Emad, Mohammad Alnatour, Walhan Alshaer, Jennifer L. Gibbs, Benoît Michot, Dana Alqudah, Alaa A. A. Aljabali, Mairvat Al-mrahleh, Abdolelah Jaradat and Duaa Abuarqoub

Cell Tissue Res, 2025, 400, 319
DOI: 10.1007/s00441-025-03962-6

Curcumin-tannic acid-poloxamer nanoassemblies enhance curcumin’s uptake and bioactivity against cancer cells in vitro

Suhair Sunoqrot, Bayan Orainee, Dana A. Alqudah, Fadwa Daoud and Walhan Alshaer

International Journal of Pharmaceutics, 2021, 610, 121255
DOI: 10.1016/j.ijpharm.2021.121255

Dual-loaded liposomal carriers to combat chemotherapeutic resistance in breast cancer

Mohamed El-Tanani, Hamdi Nsairat, Alaa A. Aljabali, Ismail I. Matalka, Alaaldin M. Alkilany and Murtaza M. Tambuwala

Expert Opinion on Drug Delivery, 2024, 21, 309
DOI: 10.1080/17425247.2024.2311812

siRNA and targeted delivery systems in breast cancer therapy

Sepideh Mirzaei, Mahshid Deldar Abad Paskeh, Maliheh Entezari, Seyed Hesamoddin Bidooki, Vahideh Javadian Ghaleh, Shamin rezaei, Elahe Sadat Hejazi, Amirabbas Kakavand, Mitra Behroozaghdam, Abolfazl Movafagh, Afshin Taheriazam, Mehrdad Hashemi and Saeed Samarghandian

Clin Transl Oncol, 2022, 25, 1167
DOI: 10.1007/s12094-022-03043-y

Non-Viral Carriers for Nucleic Acids Delivery: Fundamentals and Current Applications

Sofia Shtykalova, Dmitriy Deviatkin, Svetlana Freund, Anna Egorova and Anton Kiselev

Life, 2023, 13, 903
DOI: 10.3390/life13040903

Bioresponsive and multifunctional cyclodextrin-based non-viral nanocomplexes in cancer therapy: Building foundations for gene and drug delivery, immunotherapy and bioimaging

Qi Lu

Environmental Research, 2023, 234, 116507
DOI: 10.1016/j.envres.2023.116507

Green synthesized Zingiber officinale -ZnO nanoparticles: anticancer efficacy against 3D breast cancer model

Ruqaya Alhaddad, Bassam M Abualsoud, Ibrahim Al-Deeb and Hamdi Nsairat

Future Science OA, 2024, 10
DOI: 10.1080/20565623.2024.2419806

Innovations in Cancer Therapy: Endogenous Stimuli-Responsive Liposomes as Advanced Nanocarriers

Jazmín Torres, Johanna Karina Valenzuela Oses, Antonio María Rabasco-Álvarez, María Luisa González-Rodríguez and Mónica Cristina García

Pharmaceutics, 2025, 17, 245
DOI: 10.3390/pharmaceutics17020245

Advancements and global perspectives in the green synthesis of silver nanoparticles: A two-decade analysis

Islam Hamad, Shereen M. Aleidi, Walhan Alshaer, Shrouq Twal, Mona Al Olabi and Yasser Bustanji

PHAR, 2025, 72, 1
DOI: 10.3897/pharmacia.72.e142156

Review of recent preclinical and clinical research on ligand-targeted liposomes as delivery systems in triple negative breast cancer therapy

Mohammad Hajimolaali, Farid Abedin Dorkoosh and Sophia G. Antimisiaris

Journal of Liposome Research, 2024, 34, 671
DOI: 10.1080/08982104.2024.2325963

Analytical Approaches for Assessing Curcumin and Nicotinamide Co-Encapsulated in Liposomal Formulation: UV Spectrophotometry and HPLC Validation

Ali Fahdawi, Naeem Shalan, Zainab Lafi and Omar Markab

Jordan j. pharm. sci., 2024, 17, 468
DOI: 10.35516/jjps.v17i3.2359

Unravelling the in vivo dynamics of liposomes: Insights into biodistribution and cellular membrane interactions

Sharanya Paramshetti, Mohit Angolkar, Sirajunisa Talath, Riyaz Ali M. Osmani, Asha Spandana, Adel Al Fatease, Umme Hani, K.V.R.N.S. Ramesh and Ekta Singh

Life Sciences, 2024, 346, 122616
DOI: 10.1016/j.lfs.2024.122616

Hyaluronic Acid – Coated Niosomes for Curcumin Targeted Delivery into Breast Cancer Cells

Zahraa M. Al Zubaidi, Hamdi Nsairat, Naeem M. Shalan, Leena Al‐Asfoor, Dana A. Alqudah, Mairvat Mrahleh and Walhan Alshaer.

ChemistrySelect, 2024, 9
DOI: 10.1002/slct.202304649

Advances in aptamer technology and its updated applications in gastric cancer

Sayedeh Azimeh Hosseini, Arghavan Rakhshani Nejad, Hassan Valadbeigi, Mohammad Hossein Haddadi and Monireh Bazdar

Analytical Biochemistry, 2025, 706, 115950
DOI: 10.1016/j.ab.2025.115950

Effect of cucurbit[7]uril on DPPC-containing liposomes: Interactions with the lipid bilayer

Summay Altaher, Walhan Alshaer, Fedaa Al Adaileh, Hamdi Nsairat, Shrouq Alsotari, Majdoleen H Rababah, Abeer Al Bawab and Fadwa Odeh

Science Progress, 2025, 108
DOI: 10.1177/00368504251334687

Novel Folic Acid-Functionalized Smart Liposomes for the targeted delivery of Quercetin against cancer

Amanda N. Ngcamu, Joshua C. Nwabuife, Nokukhanya P. Ndimande, Samkelsiwe Gabela, Terisha Ghazi, Mamello P. Sekhoacha and Mbuso A. Faya

Journal of Drug Delivery Science and Technology, 2025, 107358
DOI: 10.1016/j.jddst.2025.107358

Liposome-Based Drug Delivery Systems in Cancer Research: An Analysis of Global Landscape Efforts and Achievements

Islam Hamad, Amani A. Harb and Yasser Bustanji

Pharmaceutics, 2024, 16, 400
DOI: 10.3390/pharmaceutics16030400

Formation and evaluation of doxorubicin and cromoglycate metal–organic framework for anti-cancer activity

Ebaa Abu Saleem, Zainab Lafi, Naeem Shalan, Walhan Alshaer and Imad Hamadneh

Nanomedicine, 2025, 20, 467
DOI: 10.1080/17435889.2025.2459059

Gold nanoparticles and breast cancer: A bibliometric analysis of the current state of research and future directions

Yasser Bustanji, Jalal Taneera, Mohammad H. Semreen, Eman Abu-Gharbieh, Waseem El-Huneidi, Moez Al-Islam E. Faris, Karem H. Alzoubi, Nelson C. Soares, Basil Albustanji, Ahmad Y. Abuhelwa, Rund Abu-Zurayk, Mohammad A.Y. Alqudah and Hatim S. AlKhatib

OpenNano, 2023, 12, 100164
DOI: 10.1016/j.onano.2023.100164

Unlocking the Therapeutic Potential of BCL-2 Associated Protein Family: Exploring BCL-2 Inhibitors in Cancer Therapy

Bisan El Dakkak, Jalal Taneera, Waseem El-Huneidi, Eman Abu-Gharbieh, Rifat Hamoudi, Mohammad H. Semreen, Nelson C. Soares, Eman Y. Abu-Rish, Mahmoud Y. Alkawareek, Alaaldin M. Alkilany and Yasser Bustanji

Biomol Ther (Seoul), 2024, 32, 267
DOI: 10.4062/biomolther.2023.149

Liposomes: structure, composition, types, and clinical applications

Hamdi Nsairat, Dima Khater, Usama Sayed, Fadwa Odeh, Abeer Al Bawab and Walhan Alshaer

Heliyon, 2022, 8, e09394
DOI: 10.1016/j.heliyon.2022.e09394

Liposome bilayer stability: emphasis on cholesterol and its alternatives

Hamdi Nsairat, Abed Alqader Ibrahim, Areej M. Jaber, Sharif Abdelghany, Randa Atwan, Naeem Shalan, Hiba Abdelnabi, Fadwa Odeh, Mohamed El-Tanani and Walhan Alshaer

Journal of Liposome Research, 2024, 34, 178
DOI: 10.1080/08982104.2023.2226216

Development and Validation of Reversed-Phase-HPLC Method for Simultaneous Quantification of Fulvestrant and Disulfiram in Liposomes

Hamdi Nsairat, Walhan Alshaer, Zainab Lafi, Somaya Ahmad, Alaa Al-Sanabrah and Mohamed El-Tanani

Bioanalysis, 2023, 15, 1393
DOI: 10.4155/bio-2023-0137

Self-assembly of maltose-albumin nanoparticles for efficient targeting delivery and therapy in liver cancer

Lu Wang, Yirui Wu, Niuniu Yang, Wenting Yin, Huang Yang, Conghu Li, Yan Zhuang, Ziyi Song, Xu Cheng, Shuiqing Shi and Yan Wu

International Journal of Biological Macromolecules, 2024, 258, 128691
DOI: 10.1016/j.ijbiomac.2023.128691

Phytochemical composition and antiviral properties of A. fragrantissima methanolic extract on H1N1 virus

Bashaer Abu-Irmaileh, Hamza M. Al-Hroub, Mohammad H. Rasras, Mohammad Hudaib, Mohammad H. Semreen and Yasser Bustanji

PHAR, 2025, 72, 1
DOI: 10.3897/pharmacia.72.e138108

Mitochondria-Targeted Lipid Nanoparticles Loaded with Rotenone as a New Approach for the Treatment of Oncological Diseases

Leysan Vasileva, Gulnara Gaynanova, Darya Kuznetsova, Farida Valeeva, Anna Lyubina, Syumbelya Amerhanova, Alexandra Voloshina, Guzel Sibgatullina, Dmitry Samigullin, Konstantin Petrov and Lucia Zakharova

Molecules, 2023, 28, 7229
DOI: 10.3390/molecules28207229

Selective imaging, gene, and therapeutic delivery using PEGylated and pH-Sensitive nanoparticles for enhanced lung disorder treatment

Nourhan Elsayed

International Journal of Pharmaceutics, 2024, 666, 124819
DOI: 10.1016/j.ijpharm.2024.124819

Recent advances in using liposomes for delivery of nucleic acid-based therapeutics

Hamdi Nsairat, Walhan Alshaer, Fadwa Odeh, Ezzaldeen Esawi, Dima Khater, Abeer Al Bawab, Mohamed El-Tanani, Abdalla Awidi and Mohammad S. Mubarak

OpenNano, 2023, 11, 100132
DOI: 10.1016/j.onano.2023.100132

PEGylated nanoassemblies composed of edelfosine and fulvestrant drugs: In vitro antiproliferative effect against breast cancer cells

Hamdi Nsairat, Mazen Al-Sulaibi and Walhan Alshaer

Journal of Drug Delivery Science and Technology, 2023, 85, 104612
DOI: 10.1016/j.jddst.2023.104612

Surface Functionalized Lipid Nanoparticles in Promoting Therapeutic Outcomes: An Insight View of the Dynamic Drug Delivery System

Namish Manchanda, Harish Vishkarma, Muskan Goyal, Saurabh Shah, Paras Famta, Sushama Talegaonkar and Saurabh Srivastava

CDT, 2024, 25, 278
DOI: 10.2174/0113894501285598240216065627

Novel Anticancer Triple Formula Based on Aptamer-Conjugated PEGylated Nanoliposomes

Ali Al-Samydai, Hamdi Nsairat, Moath Alqaraleh, Maha N. Abu Hajleh, Areej Jaber, Lidia Al-Halaseh, Hanan Azzam, Qasim Khalid Alazzawi, Israa Al-Ani, Simone Carradori and Walhan Alshaer

Technol Cancer Res Treat, 2025, 24
DOI: 10.1177/15330338251356548