Oncogene EVI1 drives acute myeloid leukemia via a targetable interaction with CTBP2

Dorien Pastoors, Marije Havermans, Roger Mulet-Lazaro, Duncan Brian, Willy Noort, Julius Grasel, Remco Hoogenboezem, Leonie Smeenk, Jeroen A. A. Demmers, Michael D. Milsom, Tariq Enver, Richard W. J. Groen, Eric Bindels and Ruud Delwel

Sci. Adv., 2024, 10
DOI: 10.1126/sciadv.adk9076

Rapid degradation of histone deacetylase 1 (HDAC1) reveals essential roles in both gene repression and active transcription

David M English, Samuel N Lee, Khadija A Sabat, India M Baker, Trong Khoa Pham, Mark O Collins and Shaun M Cowley

Nucleic Acids Research, 2025, 53
DOI: 10.1093/nar/gkae1223

Demethylase-independent roles of LSD1 in regulating enhancers and cell fate transition

Cheng Zeng, Jiwei Chen, Emmalee W. Cooke, Arijita Subuddhi, Eliana T. Roodman, Fei Xavier Chen and Kaixiang Cao

Nat Commun, 2023, 14
DOI: 10.1038/s41467-023-40606-1

Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1

Kwangwoon Lee, Marco Barone, Amanda L. Waterbury, Hanjie Jiang, Eunju Nam, Sarah E. DuBois-Coyne, Samuel D. Whedon, Zhipeng A. Wang, Jonatan Caroli, Katherine Neal, Brian Ibeabuchi, Zuzer Dhoondia, Mitzi I. Kuroda, Brian B. Liau, Samuel Beck, Andrea Mattevi and Philip A. Cole

Nat Chem Biol, 2025, 21, 227
DOI: 10.1038/s41589-024-01671-9

Comprehensive analysis of the proximity-dependent nuclear interactome for the oncoprotein NOTCH1 in live cells

Haydee M. Torres, Fang Fang, Danielle G. May, Paige Bosshardt, Leetoria Hinojosa, Kyle J. Roux and Jianning Tao

Journal of Biological Chemistry, 2024, 300, 105522
DOI: 10.1016/j.jbc.2023.105522

LSD1 for the Targeted Regulation of Adipose Tissue

Li Chen, Xuan Sun, Daidi Chen and Qingjun Gui

CIMB, 2022, 45, 151
DOI: 10.3390/cimb45010012

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere and Markku Varjosalo

EMBO Rep, 2024, 25, 1589
DOI: 10.1038/s44319-024-00074-0

Epigenetic Control of an Auxiliary Subunit of Voltage-Gated Sodium Channels Regulates the Strength of Drug-Cue Associations and Relapse-Like Cocaine Seeking

Daniel J. Wood, Evgeny Tsvetkov, Susana Comte-Walters, Colin L. Welsh, Michelle Bloyd, Timothy G. Wood, Rose Marie Akiki, Ethan M. Anderson, Rachel D. Penrod, Lalima K. Madan, Lauren E. Ball, Makoto Taniguchi and Christopher W. Cowan

Biological Psychiatry, 2025
DOI: 10.1016/j.biopsych.2025.01.027

CoREST in pieces: Dismantling the CoREST complex for cancer therapy and beyond

Houssam Ismail, Jalila Chagraoui and Guy Sauvageau

Sci. Adv., 2025, 11
DOI: 10.1126/sciadv.ads6556

Investigation of SAMD1 ablation in mice

Bruce Campbell, Lisa M. Weber, Sandra J. Engle, Terence R. S. Ozolinš, Patricia Bourassa, Robert Aiello and Robert Liefke

Sci Rep, 2023, 13
DOI: 10.1038/s41598-023-29779-3

Determining DNA–Protein Binding Affinities and Specificities from Crude Lysates Using a Combined SILAC/TMT Labeling Strategy

Cathrin Gräwe, Miguel Hernandez-Quiles, Pascal W. T. C. Jansen, Annika Brimmers and Michiel Vermeulen

J. Proteome Res., 2023, 22, 2683
DOI: 10.1021/acs.jproteome.3c00248

Distinct biochemical properties of the class I histone deacetylase complexes

Kwangwoon Lee, Samuel D. Whedon, Zhipeng A. Wang and Philip A. Cole

Current Opinion in Chemical Biology, 2022, 70, 102179
DOI: 10.1016/j.cbpa.2022.102179

GSE1 links the HDAC1/CoREST co-repressor complex to DNA damage

Terezia Vcelkova, Wolfgang Reiter, Martha Zylka, David M Hollenstein, Stefan Schuckert, Markus Hartl and Christian Seiser

Nucleic Acids Research, 2023, 51, 11748
DOI: 10.1093/nar/gkad911

Synaptic Deficits in Adnp‐Mutant Mice Are Ameliorated by Histone Demethylase LSD1 Inhibition

Chih‐Hung Lin, Yong Ren, Kin Wai Tam, Megan Conrow‐Graham and Zhen Yan

Autism Research, 2025, 18, 1342
DOI: 10.1002/aur.70069