Grassystatin G, a new cathepsin D inhibitor from marine cyanobacteria: discovery, synthesis, and biological characterization

Lobna A. Elsadek, Gustavo Seabra, Valerie J. Paul and Hendrik Luesch

RSC Med. Chem., 2025, 16, 3108
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Direct pathway cloning and expression of the radiosumin biosynthetic gene cluster

Xiaodan Ouyang, Paul M. D'Agostino, Matti Wahlsten, Endrews Delbaje, Jouni Jokela, Perttu Permi, Greta Gaiani, Antti Poso, Piia Bartos, Tobias A. M. Gulder, Hannu Koistinen and David P. Fewer

Org. Biomol. Chem., 2023, 21, 4893
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Progress in the discovery and development of anticancer agents from marine cyanobacteria

Hendrik Luesch, Emma K. Ellis, Qi-Yin Chen and Ranjala Ratnayake

Nat. Prod. Rep., 2025, 42, 208
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Increasing trends of overweight and obesity in treatment-naive people living with HIV in Shenzhen from 2014 to 2020: an emerging health concern

Tianze Li, Liqin Sun, Yun He, Yang Zhou, Liumei Xu, Fang Zhao, Dongsheng Hu, Hui Wang, Hongzhou Lu and Jiaye Liu

Front. Public Health, 2023, 11
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Synthesis and bioevaluation of Scutellarein-Tertramethylpyrazine hybrid molecules for the treatment of ischemic stroke

Yongxi Dong, Fang Wang, Jinlan Wen, Yongqing Mao, Shanhui Zhang, Tiemei Long, Zhangxiang Yang, Lei Li, Jiquan Zhang, Li Dong, Gang Liu and Jianwei Xu

Bioorganic Chemistry, 2024, 142, 106978
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Native metabolomics identifies the rivulariapeptolide family of protease inhibitors

Raphael Reher, Allegra T. Aron, Pavla Fajtová, Paolo Stincone, Berenike Wagner, Alicia I. Pérez-Lorente, Chenxi Liu, Ido Y. Ben Shalom, Wout Bittremieux, Mingxun Wang, Kyowon Jeong, Marie L. Matos-Hernandez, Kelsey L. Alexander, Eduardo J. Caro-Diaz, C. Benjamin Naman, J. H. William Scanlan, Phil M. M. Hochban, Wibke E. Diederich, Carlos Molina-Santiago, Diego Romero, Khaled A. Selim, Peter Sass, Heike Brötz-Oesterhelt, Chambers C. Hughes, Pieter C. Dorrestein, Anthony J. O’Donoghue, William H. Gerwick and Daniel Petras

Nat Commun, 2022, 13
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Astragalus polysaccharide protects experimental colitis through an aryl hydrocarbon receptor‐dependent autophagy mechanism

Yi Ying, Li‐yun Song, Wen‐lin Pang, Si‐qi Zhang, Jing‐ze Yu, Peng‐tao Liang, Tian‐gang Li, Yi Sun, Yin‐ying Wang, Jin‐yuan Yan and Zhong‐shan Yang

British J Pharmacology, 2024, 181, 681
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The Structure-property Relationships of Clinically Approved Protease Inhibitors

Kihang Choi

CMC, 2024, 31, 1441
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Engineering of marizomib loaded polymeric nanoparticles: In vivo safety profile and In vitro proliferation in hepatocellular carcinoma

Lulu Sui, Gang Xu, Ying Hao, Xiaolei Wang and Kun Tang

Journal of Drug Delivery Science and Technology, 2021, 66, 102840
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Withaferin A inhibits proliferation of human endometrial cancer cells via transforming growth factor-β (TGF-β) signalling

Kejun Xu, Hongyan Shi, Yongming Du and Jilan Ou

3 Biotech, 2021, 11
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Structural and biochemical studies of an iterative ribosomal peptide macrocyclase

Gengnan Li, Krishna Patel, Yi Zhang, Jackson K. Pugmire, Yousong Ding and Steven D. Bruner

Proteins, 2022, 90, 670
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Protacs in oral cancer: degrading oncogenic drivers for next-generation therapy

Pratibha Prasad, Manal Jamil Al Maslamani, Khuzin Dinislam, Syed Tasqeruddin and Anas Shamsi

Front. Oral Health, 2026, 7
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Diversity, molecular mechanisms and structure-activity relationships of marine protease inhibitors—A review

Abdur Rauf, Anees Ahmed Khalil, Ahmed Olatunde, Muneeb Khan, Sirajudheen Anwar, Ahmed Alafnan and Kannan RR Rengasamy

Pharmacological Research, 2021, 166, 105521
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Ahp-Cyclodepsipeptides as tunable inhibitors of human neutrophil elastase and kallikrein 7: Total synthesis of tutuilamide A, serine protease selectivity profile and comparison with lyngbyastatin 7

Qi-Yin Chen, Danmeng Luo, Gustavo M. Seabra and Hendrik Luesch

Bioorganic & Medicinal Chemistry, 2020, 28, 115756
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Potentials of marine natural products against malaria, leishmaniasis, and trypanosomiasis parasites: a review of recent articles

Justus Amuche Nweze, Florence N. Mbaoji, Yan-Ming Li, Li-Yan Yang, Shu-Shi Huang, Vincent N. Chigor, Emmanuel A. Eze, Li-Xia Pan, Ting Zhang and Deng-Feng Yang

Infect Dis Poverty, 2021, 10
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Advancements, challenges, and future frontiers in covalent inhibitors and covalent drugs: A review

Muhammad Salman Hameed, Hongxuan Cao, Li Guo, Lei Zeng and Yanliang Ren

European Journal of Medicinal Chemistry Reports, 2024, 12, 100217
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Eryngium creticum L.: Chemical Characterization, SARS-CoV-2 Inhibitory Activity, and In Silico Study

Marwa Elsbaey, Mahmoud A. A. Ibrahim, Ahmed M. Shawky and Tomofumi Miyamoto

ACS Omega, 2022, 7, 22725
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Diagnostic and therapeutic potential of protease inhibition

Natalia Ćwilichowska, Karolina W. Świderska, Agnieszka Dobrzyń, Marcin Drąg and Marcin Poręba

Molecular Aspects of Medicine, 2022, 88, 101144
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UPLC-Q–TOF–MS, network analysis, and molecular docking to investigate the effect and active ingredients of tea-seed oil against bacterial pathogens

Yan Duan, Li-Juan Zhao, Yan-Hui Zhou, Qi-Zhi Zhou, Ai-Qing Fang, Yu-Ting Huang, Yuan Ma, Zhi Wang, Yu-Ting Lu, Yu-Ping Dai, Shun-Xiang Li and Juan Li

Front. Pharmacol., 2023, 14
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Natural Compounds as Protease Inhibitors in Therapeutic Focus on Cancer Therapy

Bhadra Kakali

ACAMC, 2024, 24, 1167
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Converging frontiers in cancer treatment: the role of nanomaterials, mesenchymal stem cells, and microbial agents—challenges and limitations

Hamed Afkhami, Aref Yarahmadi, Shoroq Bostani, Nahid Yarian, Mahdieh Sadat Haddad, Shima Sadat Lesani, Seyed Soheil Aghaei and Mohammad Reza Zolfaghari

Discov Onc, 2024, 15
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