Cross Reference Logo
Citations to this article as recorded by CrossRef and RSC Journals (135 citations).

Biological applications of water-soluble polypeptides with ordered secondary structures
Chenglong Ge, Huan Ye, Fan Wu, Junliang Zhu, Ziyuan Song, Yong Liu and Lichen Yin
J. Mater. Chem. B, 2020, 8, 6530
DOI: 10.1039/D0TB00902D

A “self-accelerating endosomal escape” siRNA delivery nanosystem for significantly suppressing hyperplasia via blocking the ERK2 pathway
Bin Gao, Qiaoping Zhang, Xiaoyu Wang, Meiyu Wang, Xiang-kui Ren, Jintang Guo, Shihai Xia, Wencheng Zhang and Yakai Feng
Biomater. Sci., 2019, 7, 3307
DOI: 10.1039/C9BM00451C

Chemically modified and conjugated antimicrobial peptides against superbugs
Wenyi Li, Frances Separovic, Neil M. O'Brien-Simpson and John D. Wade
Chem. Soc. Rev., 2021, 50, 4932
DOI: 10.1039/D0CS01026J

Synthesis of modifiable photo-responsive polypeptides bearing allyloxyazobenzene side-chains
Wei Xiong, Chong Zhang, Xiaolin Lyu, Hantao Zhou, Wenying Chang, Yu Bo, Erqiang Chen, Zhihao Shen and Hua Lu
Polym. Chem., 2020, 11, 439
DOI: 10.1039/C9PY01106D

Tetrazine- andtrans-cyclooctene-functionalised polypept(o)ides for fast bioorthogonal tetrazine ligation
Kerstin Johann, Dennis Svatunek, Christine Seidl, Silvia Rizzelli, Tobias A. Bauer, Lydia Braun, Kaloian Koynov, Hannes Mikula and Matthias Barz
Polym. Chem., 2020, 11, 4396
DOI: 10.1039/D0PY00375A

Manipulating the helix–coil transition profile of synthetic polypeptides by leveraging side-chain molecular interactions
Ziyuan Song, Zhengzhong Tan, Xuetao Zheng, Zihuan Fu, Ettigounder Ponnusamy and Jianjun Cheng
Polym. Chem., 2020, 11, 1445
DOI: 10.1039/C9PY01857C

Organobase 1,1,3,3-tetramethyl guanidine catalyzed rapid ring-opening polymerization of α-amino acid N-carboxyanhydrides adaptive to amine, alcohol and carboxyl acid initiators
Kai Li, Zheng Li, Yong Shen, Xiaohui Fu, Chongyi Chen and Zhibo Li
Polym. Chem., 2022, 13, 586
DOI: 10.1039/D1PY01508G

Synthesis of water soluble and multi-responsive selenopolypeptides via ring-opening polymerization of N-carboxyanhydrides
Guangqi Wu, Chenglong Ge, Xingyi Liu, Shuo Wang, Letian Wang, Lichen Yin and Hua Lu
Chem. Commun., 2019, 55, 7860
DOI: 10.1039/C9CC03767E

N-Sulfonyl amidine polypeptides: new polymeric biomaterials with conformation transition responsive to tumor acidity
Xiang Xu, Jinjuan Ma, Aiguo Wang and Nan Zheng
Chem. Sci., 2024, 15, 1769
DOI: 10.1039/D3SC05504C

Aqueous ROPISA of α-amino acid N-carboxyanhydrides: polypeptide block secondary structure controls nanoparticle shape anisotropy
Chloé Grazon, Pedro Salas-Ambrosio, Ségolène Antoine, Emmanuel Ibarboure, Olivier Sandre, Andrew J. Clulow, Ben J. Boyd, Mark W. Grinstaff, Sébastien Lecommandoux and Colin Bonduelle
Polym. Chem., 2021, 12, 6242
DOI: 10.1039/D1PY00995H

Control of the structure and morphology of polypeptide/surfactant spread films by exploiting specific interactions
Javier Carrascosa-Tejedor, Laura M. Miñarro, Marina Efstratiou, Imre Varga, Maximilian W. A. Skoda, Philipp Gutfreund, Armando Maestro, M. Jayne Lawrence and Richard A. Campbell
Nanoscale, 2023, 15, 11141
DOI: 10.1039/D2NR07164A

Self-polymerization of Meldrum's acid-amine compounds: an effective route to polyamides
Chien-Ho Huang and Ying-Ling Liu
Polym. Chem., 2021, 12, 291
DOI: 10.1039/D0PY01341B

Light-induced twisting, untwisting, and retwisting of aromatic polyamides: an interplay between the induced chirality and the co-facial π-stacking interactions
Subhendu Samanta and Raj Kumar Roy
Chem. Sci., 2025, 16, 10325
DOI: 10.1039/D4SC08795J

Antifouling polymers for nanomedicine and surfaces: recent advances
Yi Jie Eng, Tuan Minh Nguyen, He-Kuan Luo and Julian M. W. Chan
Nanoscale, 2023, 15, 15472
DOI: 10.1039/D3NR03164K

Combining simulations and experiments for the molecular engineering of multifunctional collagen mimetic peptide-based materials
Amber M. Hilderbrand, Phillip A. Taylor, Francesca Stanzione, Mark LaRue, Chen Guo, Arthi Jayaraman and April M. Kloxin
Soft Matter, 2021, 17, 1985
DOI: 10.1039/D0SM01562H

Versatile fully-substituted triazole-functionalized polypeptides with a stable α-helical conformation for gene delivery
Xiang Xu, Shuxin Liu, He Gao, Ming Li, Junnan He, Yubin Zheng, Wangze Song and Nan Zheng
Polym. Chem., 2022, 13, 5042
DOI: 10.1039/D2PY00894G

Application of functional peptides in the electrochemical and optical biosensing of cancer biomarkers
Yue Cao, Liang Zhou, Zhikai Fang, Zihan Zou, Jing Zhao, Xiaolei Zuo and Genxi Li
Chem. Commun., 2023, 59, 3383
DOI: 10.1039/D2CC06824A

Ring opening polymerization of α-amino acids: advances in synthesis, architecture and applications of polypeptides and their hybrids
Alicia Rasines Mazo, Stephanie Allison-Logan, Fatemeh Karimi, Nicholas Jun-An Chan, Wenlian Qiu, Wei Duan, Neil M. O’Brien-Simpson and Greg G. Qiao
Chem. Soc. Rev., 2020, 49, 4737
DOI: 10.1039/C9CS00738E

Open-air synthesis of oligo(ethylene glycol)-functionalized polypeptides from non-purified N-carboxyanhydrides
Zhengzhong Tan, Ziyuan Song, Tianrui Xue, Lining Zheng, Lei Jiang, Yunjiang Jiang, Zihuan Fu, Anh Nguyen, Cecilia Leal and Jianjun Cheng
Biomater. Sci., 2021, 9, 4120
DOI: 10.1039/D1BM00223F

Photo-responsive Self-Reducible Polymers: Overcoming the Spatiotemporal Barriers for Hypersensitivity
Chuang Weng, Haodong Chen, Taoran Xu, Zifen Li, Xinfu Liu, Mingming Ding, Qin Zhang, Hong Tan and Qiang Fu
ACS Materials Lett., 2020, 2, 602
DOI: 10.1021/acsmaterialslett.0c00070

Oxidation Responsive PEGylated Polyamino Acid Bearing Thioether Pendants for Enhanced Anticancer Drug Delivery
Yitao Sun, Yu Zhang, Xin Guo, Yanping Wang, Pan He and Chunsheng Xiao
Macromolecular Bioscience, 2023, 23
DOI: 10.1002/mabi.202200498

Accelerated Polypeptide Synthesis via N‐Carboxyanhydride Ring Opening Polymerization in Continuous Flow
Jeroen Hendrik Vrijsen, Alicia Rasines Mazo, Tanja Junkers and Greg Guanghua Qiao
Macromol. Rapid Commun., 2020, 41
DOI: 10.1002/marc.202000071

A 3D-polyphenylalanine network inside porous alumina: Synthesis and characterization of an inorganic–organic composite membrane
Jonathan Stott and Jörg J Schneider
Beilstein J. Nanotechnol., 2020, 11, 938
DOI: 10.3762/bjnano.11.78

Synthetic cationic helical polypeptides for the stimulation of antitumour innate immune pathways in antigen-presenting cells
DaeYong Lee, Kristin Huntoon, Yifan Wang, Minjeong Kang, Yifei Lu, Seong Dong Jeong, Todd M. Link, Thomas D. Gallup, Yaqing Qie, Xuefeng Li, Shiyan Dong, Benjamin R. Schrank, Adam J. Grippin, Abin Antony, JongHoon Ha, Mengyu Chang, Yi An, Liang Wang, Dadi Jiang, Jing Li, Albert C. Koong, John A. Tainer, Wen Jiang and Betty Y. S. Kim
Nat. Biomed. Eng, 2024, 8, 593
DOI: 10.1038/s41551-024-01194-7

Intrinsically fluorescent polyureas toward conformation-assisted metamorphosis, discoloration and intracellular drug delivery
Yeqiang Zhou, Fan Fan, Jinling Zhao, Zhaoding Wang, Rui Wang, Yi Zheng, Hang Liu, Chuan Peng, Jianshu Li, Hong Tan, Qiang Fu and Mingming Ding
Nat Commun, 2022, 13
DOI: 10.1038/s41467-022-32053-1

Ordered Conformation‐Regulated Vesicular Membrane Permeability
Yi Zheng, Zuojie Wang, Zifen Li, Hang Liu, Jing Wei, Chuan Peng, Yeqiang Zhou, Jianshu Li, Qiang Fu, Hong Tan and Mingming Ding
Angew Chem Int Ed, 2021, 60, 22529
DOI: 10.1002/anie.202109637

Cyclic Poly(α-amino acid) Quaternary Ammonium Salt with Potent Antibacterial Activity and Low Toxicity
Guowenlie Gao, Wenlong Zhang, Yongchang Tian, Ting Hua, Pengqi Wan, Chunsheng Xiao and Xuesi Chen
Biomacromolecules, 2025, 26, 3805
DOI: 10.1021/acs.biomac.5c00407

Liquid crystalline composite hydrogels with large pH-triggered anisotropic swelling for embolotherapy
Yujie Zhang, Ying Luo, Sijia Gao, Lei Zou, Ying Guan and Yongjun Zhang
Acta Biomaterialia, 2024, 174, 206
DOI: 10.1016/j.actbio.2023.12.016

Recent advances in design of antimicrobial peptides and polypeptides toward clinical translation
Yunjiang Jiang, Yingying Chen, Ziyuan Song, Zhengzhong Tan and Jianjun Cheng
Advanced Drug Delivery Reviews, 2021, 170, 261
DOI: 10.1016/j.addr.2020.12.016

Application of Bifunctional Thiourea Catalyst in One Pot Preparation of Polypeptides and Cyclic Carbonates
Kaiyue Wang, Mingnuo Xu, Bo Li and Guangpeng Wu
Chinese Journal of Organic Chemistry, 2024, 44, 3206
DOI: 10.6023/cjoc202405031

Chiral Polymer Micelles Alleviate Adriamycin Cardiotoxicity via Iron Chelation and Ferroptosis Inhibition
Tiantian Chen, Yan Qin, Yao Li, Yaru Li, Jiajia Luo, Lanlan Fan, Meiyu Feng, Zheng Wang and Yanjun Zhao
Adv Funct Materials, 2023, 33
DOI: 10.1002/adfm.202300689

Tailored Polypeptide Star Copolymers for 3D Printing of Bacterial Composites Via Direct Ink Writing
Robert D. Murphy, Ronnie V. Garcia, Seung J. Oh, Tanner J. Wood, Kyoo D. Jo, Javier Read de Alaniz, Ed Perkins and Craig J. Hawker
Advanced Materials, 2023, 35
DOI: 10.1002/adma.202207542

Cooperative Covalent Polymerization of N-carboxyanhydrides: from Kinetic Studies to Efficient Synthesis of Polypeptide Materials
Wanying Wang, Hailin Fu, Yao Lin, Jianjun Cheng and Ziyuan Song
Acc. Mater. Res., 2023, 4, 604
DOI: 10.1021/accountsmr.3c00046

Chirality-Governed UCST Behavior in Polypeptides
Yali Liu, Chuanzhuang Zhao and Chongyi Chen
Macromolecules, 2022, 55, 3801
DOI: 10.1021/acs.macromol.2c00291

Single‐Step, Rapid, and Mild Synthesis of β‐Amino Acid N‐Carboxy Anhydrides Using Micro‐Flow Technology
Naoto Sugisawa, Yuma Otake, Hiroyuki Nakamura and Shinichiro Fuse
Chemistry — An Asian Journal, 2020, 15, 79
DOI: 10.1002/asia.201901429

One-Shot Synthesis of Peptide Amphiphiles with Applications in Directed Graphenic Assembly
Karoline E. Eckhart, Francesca A. Starvaggi and Stefanie A. Sydlik
Biomacromolecules, 2020, 21, 3878
DOI: 10.1021/acs.biomac.0c00962

Thiourea-Based Bifunctional Catalysts for Epoxide-Involved Ring-Opening Polymerization of α-Amino Acid N-Carboxyanhydrides
Kai-Yue Wang, Zhuo-Qun Li, Ming-Nuo Xu and Bo Li
Macromolecules, 2023, 56, 5599
DOI: 10.1021/acs.macromol.3c00830

Polypeptide-based vapor-responsive porous poly(ionic liquid) actuators: From reversible to unexpectedly irreversible actuation
Shuhe Wei, Yan Xiao, Hanwen Jiang, Frédéric Héraly, Liangshun Zhang, Wanyi Huang, Jiayin Yuan and Meidong Lang
Materials Today Communications, 2023, 35, 105878
DOI: 10.1016/j.mtcomm.2023.105878

Synthesis of Polypeptides with High-Fidelity Terminal Functionalities under NCA Monomer-Starved Conditions
Lei Li, Jie Cen, Wenhao Pan, Yuben Zhang, Xuanxi Leng, Zhengqi Tan, Hao Yin and Shiyong Liu
Research, 2021, 2021
DOI: 10.34133/2021/9826046

Chirality-Regulated Clusteroluminescence in Polypeptides
Wangtao Zhao, Mei Gao, Liufen Kong, Shunfeng Yu, Chuanzhuang Zhao and Chongyi Chen
Biomacromolecules, 2024, 25, 1897
DOI: 10.1021/acs.biomac.3c01328

Protein PEPylation: A New Paradigm of Protein–Polymer Conjugation
Yingqin Hou and Hua Lu
Bioconjugate Chem., 2019, 30, 1604
DOI: 10.1021/acs.bioconjchem.9b00236

Chemoenzymatic copolymerization of glycine with serine: effects on polypeptide structure and solubility
Kayo Terada, Shogo Takemura, Kousuke Tsuchiya and Keiji Numata
Chemistry Letters, 2025, 54
DOI: 10.1093/chemle/upaf081

Strategies for the Development of pH-Responsive Synthetic Polypeptides and Polymer-Peptide Hybrids: Recent Advancements
Cintya Dharmayanti, Todd A. Gillam, Manuela Klingler-Hoffmann, Hugo Albrecht and Anton Blencowe
Polymers, 2021, 13, 624
DOI: 10.3390/polym13040624

Controlled Block Polypeptide Composed of d-Type Amino Acids: A Therapeutics Delivery Platform to Inhibit Biofilm Formation of Drug-Resistant Bacteria
Mingsheng Chen, Songhe Zhang and Zhenli He
ACS Appl. Bio Mater., 2020, 3, 6343
DOI: 10.1021/acsabm.0c00795

Accelerated polymerization of N-carboxyanhydrides catalyzed by crown ether
Yingchun Xia, Ziyuan Song, Zhengzhong Tan, Tianrui Xue, Shiqi Wei, Lingyang Zhu, Yingfeng Yang, Hailin Fu, Yunjiang Jiang, Yao Lin, Yanbing Lu, Andrew L. Ferguson and Jianjun Cheng
Nat Commun, 2021, 12
DOI: 10.1038/s41467-020-20724-w

Modulation of polymerization rate of N-carboxyanhydrides in a biphasic system
Guonan Ji, Xuetao Zheng, Xiangdie Hou, Xiao Sun, Shijie Wang, Xiaohong Li, Jianjun Cheng and Ziyuan Song
Chinese Chemical Letters, 2024, 35, 108872
DOI: 10.1016/j.cclet.2023.108872

Secondary Structure-Governed Phase Separation Behavior in Glutamate-Based Polypeptides
Mei Gao, Yali Liu, Chuanzhuang Zhao and Chongyi Chen
Biomacromolecules, 2023, 24, 3283
DOI: 10.1021/acs.biomac.3c00322

Thermoresponsive Helical Dendronized Poly(phenylacetylene)s: Remarkable Stabilization of Their Helicity via Photo-Dimerization of the Dendritic Pendants
Liangxuan Ren, Xueting Lu, Wen Li, Jiatao Yan, Andrew K. Whittaker and Afang Zhang
J. Am. Chem. Soc., 2023
DOI: 10.1021/jacs.3c09333

Helix-specific properties and applications in synthetic polypeptides
Ning Li, Yuheng Lei, Ziyuan Song and Lichen Yin
Current Opinion in Solid State and Materials Science, 2023, 27, 101104
DOI: 10.1016/j.cossms.2023.101104

Crystal Structures of Lignocellulosic Furfuryl Biobased Polydiacetylenes with Hydrogen-Bond Networks: Influencing the Direction of Solid-State Polymerization through Modification of the Spacer Length
Pierre Baillargeon, Raphaël Robidas, Olivier Toulgoat, Zacharie Michaud, Claude Y. Legault and Tarik Rahem
Crystal Growth & Design, 2022, 22, 2812
DOI: 10.1021/acs.cgd.2c00307

Doubly chiral pseudopeptidic macrobicyclic molecular cages: Water-assisted dynamic covalent self-assembly and chiral self-sorting
Ferran Esteve, Belén Altava, Eduardo García-Verdugo, Santiago V. Luis and Jean-Marie Lehn
Chem, 2022, 8, 2023
DOI: 10.1016/j.chempr.2022.04.007

Protein‐Inspired Polymers with Metal‐Site‐Regulated Ordered Conformations
Hang Liu, Yeqiang Zhou, Yang Liu, Zuojie Wang, Yi Zheng, Chuan Peng, Meng Tian, Qin Zhang, Jianshu Li, Hong Tan, Qiang Fu and Mingming Ding
Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202213000

Polysaccharides based biopolymers for biomedical applications: A review
Nazish Jabeen and Muhammad Atif
Polymers for Advanced Techs, 2024, 35
DOI: 10.1002/pat.6203

Structure and Oxidation Effects on Conformation and Thermoresponsiveness of the OEGylated Poly(glutamic acid)-Bearing Side-Chain Thioether Linkers
Xueyuan Chen, Junyang Zhong, Xinlin Jiang, Ziqing He, Yusi Quan, Songjing Zhong, Guangji Li and Yugang Huang
Langmuir, 2021, 37, 1288
DOI: 10.1021/acs.langmuir.0c03351

Robust Strategy for Antibody–Polymer–Drug Conjugation: Significance of Conjugating Orientation and Linker Charge on Targeting Ability
Jiaxun Wan, Yongjing Li, Ke Jin, Jia Guo, Jiangtao Xu and Changchun Wang
ACS Appl. Mater. Interfaces, 2020, 12, 23717
DOI: 10.1021/acsami.0c04471

Methionine-Based pH and Oxidation Dual-Responsive Block Copolymer: Synthesis and Fabrication of Protein Nanogels
Shuqi Dong, Yanfen Jiang, Guoyang Qin, Li Liu and Hanying Zhao
Biomacromolecules, 2020, 21, 4063
DOI: 10.1021/acs.biomac.0c00879

In Situ Forming and Reversibly Cross-Linkable Hydrogels Based on Copolypept(o)ides and Polysaccharides
Yanping Tong, Zhaochuang Wang, Yan Xiao, Wei Liu, Jinghao Pan, Yan Zhou and Meidong Lang
ACS Appl. Bio Mater., 2019, 2, 4545
DOI: 10.1021/acsabm.9b00668

A nanoscale MOF-based heterogeneous catalytic system for the polymerization of N-carboxyanhydrides enables direct routes toward both polypeptides and related hybrid materials
Ying Liu, Zhongwu Ren, Nannan Zhang, Xiaoxin Yang, Qihua Wu, Zehong Cheng, Hang Xing and Yugang Bai
Nat Commun, 2023, 14
DOI: 10.1038/s41467-023-41252-3

Amplified circularly polarized luminescence promoted by hierarchical self-assembly involving Pt···Pt interactions
Gui-Fei Huo, Qian Tu, Yi-Xiong Hu, Bo Jiang, Qi-Feng Zhou, Yanfei Niu, Xiaoli Zhao, Hong-Ming Ding, Jin Wen, Guang-Qiang Yin, Xueliang Shi and Lin Xu
Sci. China Mater., 2022, 65, 469
DOI: 10.1007/s40843-021-1750-9

Form Equals Function: Influence of Coacervate Architecture on Drug Delivery Applications
Chaeyoung Lim and Whitney C. Blocher McTigue
ACS Biomater. Sci. Eng., 2024, 10, 6766
DOI: 10.1021/acsbiomaterials.4c01105

Facile Synthesis of Helical Multiblock Copolypeptides: Minimal Side Reactions with Accelerated Polymerization of N-Carboxyanhydrides
Xuefang Wang, Ziyuan Song, Zhengzhong Tan, Lingyang Zhu, Tianrui Xue, Shixian Lv, Zihuan Fu, Xuetao Zheng, Jie Ren and Jianjun Cheng
ACS Macro Lett., 2019, 8, 1517
DOI: 10.1021/acsmacrolett.9b00784

Redox-Mediated Reversible Supramolecular Assemblies Driven by Switch and Interplay of Peptide Secondary Structures
Qingxin Yao, Guangqi Wu, Hao Hao, Hua Lu and Yuan Gao
Biomacromolecules, 2021, 22, 2563
DOI: 10.1021/acs.biomac.1c00300

One-Step Synthesis of Sequence-Defined Polypeptide-block-polyester by Lewis Pair-Catalyzed Chemo-Selective Copolymerization
Xiaoyan Fu, Xuming Lin, Mingqian Wang, Zhiqiang Ding, Guiqiu Ma, Bin Wang and Yuesheng Li
Macromolecules, 2024, 57, 5691
DOI: 10.1021/acs.macromol.4c00432

Polypeptide-based drug delivery systems for programmed release
Xu Wang, Ziyuan Song, Shiqi Wei, Guonan Ji, Xuetao Zheng, Zihuan Fu and Jianjun Cheng
Biomaterials, 2021, 275, 120913
DOI: 10.1016/j.biomaterials.2021.120913

Synthesis and Self‐assembly of a Helical Polymer Grafted from a Foldable Polyurethane Scaffold
Ranajit Barman, Pradip Dey, Tathagata Mondal and Suhrit Ghosh
Chemistry — An Asian Journal, 2019, 14, 4741
DOI: 10.1002/asia.201901119

Photoresponsive Polypeptide-Glycosylated Dendron Amphiphiles: UV-Triggered Polymersomes, OVA Release, and In Vitro Enhanced Uptake and Immune Response
Yingying Song, Yanzheng Chen, Pan Li and Chang-Ming Dong
Biomacromolecules, 2020, 21, 5345
DOI: 10.1021/acs.biomac.0c01465

Helical polymers for biological and medical applications
Thomas Leigh and Paco Fernandez-Trillo
Nat Rev Chem, 2020, 4, 291
DOI: 10.1038/s41570-020-0180-5

Enzyme-Activatable Interferon–Poly(α-amino acid) Conjugates for Tumor Microenvironment Potentiation
Hao Wang, Yingqin Hou, Yali Hu, Jiaxiang Dou, Youqing Shen, Yucai Wang and Hua Lu
Biomacromolecules, 2019, 20, 3000
DOI: 10.1021/acs.biomac.9b00560

Secondary Structure in Overcoming Photosensitizers’ Aggregation: α‐Helical Polypeptides for Enhanced Photodynamic Therapy
Xiang Xu, Jinjuan Ma, Yubin Zheng, Shaolei Wang, Aiguo Wang and Nan Zheng
Adv Healthcare Materials, 2023, 12
DOI: 10.1002/adhm.202203386

Self‐Assembly of Poly(Amino Acid)s Mediated by Secondary Conformations
Zifen Li, Yi Zheng, Jingyue Yan, Yue Yan, Chuan Peng, Zuojie Wang, Hang Liu, Yang Liu, Yeqiang Zhou and Mingming Ding
ChemBioChem, 2023, 24
DOI: 10.1002/cbic.202300132

Efficient Gene Delivery of Tailored Amphiphilic Polypeptides by Polyplex Surfing
Paul Klemm, Jana I. Solomun, Marko Rodewald, Maren T. Kuchenbrod, Veit G. Hänsch, Friederike Richter, Jürgen Popp, Christian Hertweck, Stephanie Hoeppener, Colin Bonduelle, Sébastien Lecommandoux, Anja Traeger and Stephanie Schubert
Biomacromolecules, 2022, 23, 4718
DOI: 10.1021/acs.biomac.2c00919

Tailoring Writability and Performance of Star Block Copolypeptides Hydrogels through Side‐Chain Design
Ronnie V. Garcia, Elizabeth A. Murphy, Nairiti J. Sinha, Yoichi Okayama, Juan Manuel Urueña, Matthew E. Helgeson, Christopher M. Bates, Craig J. Hawker, Robert D. Murphy and Javier Read de Alaniz
Small, 2023, 19
DOI: 10.1002/smll.202302794

Synthesis of AIE polyethylene glycol-block-polypeptide bioconjugates and cell uptake assessments of their self-assembled nanoparticles
Mingguang Yu, Songjing Zhong, Yusi Quan, Houhe Liu, Junyang Zhong, Xinlin Jiang, Yisi Wang, Guodong Ye, Chunping Ma and Yugang Huang
Dyes and Pigments, 2019, 170, 107640
DOI: 10.1016/j.dyepig.2019.107640

Influence of Sulfoxide Group Placement on Polypeptide Conformational Stability
Eric G. Gharakhanian, Ehab Bahrun and Timothy J. Deming
J. Am. Chem. Soc., 2019, 141, 14530
DOI: 10.1021/jacs.9b07223

Spotting Trends in Organocatalyzed and Other Organomediated (De)polymerizations and Polymer Functionalizations
María Valle, Marta Ximenis, Xabier Lopez de Pariza, Julian M. W. Chan and Haritz Sardon
Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202203043

Therapeutic potential of polypeptide-based conjugates: Rational design and analytical tools that can boost clinical translation
Tetiana Melnyk, Snežana Đorđević, Inmaculada Conejos-Sánchez and María J. Vicent
Advanced Drug Delivery Reviews, 2020, 160, 136
DOI: 10.1016/j.addr.2020.10.007

Bacterial Phospholipid-Inducible Helix-Transformable Antimicrobial Polypeptides
Xinshuang Zhang, Dong Luo, Rongqing Xia, Kangxiu Wu, Xueyi Li, Jingxian Chen, Huosheng Zhou, Jie Hu, Songyin Huang, Shuyi Jia, Chengrun Li, Yan Bao, Houbing Zhang, Liping Zhao, Lu Cai and Menghua Xiong
J. Am. Chem. Soc., 2025
DOI: 10.1021/jacs.5c14236

Superfast and Water‐Insensitive Polymerization on α‐Amino Acid N‐Carboxyanhydrides to Prepare Polypeptides Using Tetraalkylammonium Carboxylate as the Initiator
Yueming Wu, Kang Chen, Xue Wu, Longqiang Liu, Weiwei Zhang, Yun Ding, Shiqi Liu, Min Zhou, Ning Shao, Zhemin Ji, Jiacheng Chen, Minghui Zhu and Runhui Liu
Angewandte Chemie, 2021, 133, 26267
DOI: 10.1002/ange.202103540

Rapidly Thermoreversible and Biodegradable Polypeptide Hydrogels with Sol–Gel–Sol Transition Dependent on Subtle Manipulation of Side Groups
Dan Zhao, Dong Li, Fenli Quan, Yuhao Zhou, Zhen Zhang, Xuesi Chen and Chaoliang He
Biomacromolecules, 2021, 22, 3522
DOI: 10.1021/acs.biomac.1c00583

A visualizable strategy to real-time monitor chiral block copolypeptide assembly by AIE fluorescent probes
Zenghao Li, Yanan Liu and Jing Sun
Supramolecular Materials, 2024, 3, 100065
DOI: 10.1016/j.supmat.2024.100065

Secondary Structures in Synthetic Poly(Amino Acids): Homo‐ and Copolymers of Poly(Aib), Poly(Glu), and Poly(Asp)
Matthias Rohmer, Jan Freudenberg and Wolfgang Hubertus Binder
Macromolecular Bioscience, 2023, 23
DOI: 10.1002/mabi.202200344

Design and Update of Multifunctional Polypeptides and Their Applications for the Prevention of Viral Infections and Cancer Immunotherapies
Yanzheng Chen, Yingying Song, Xinyuan Zhu, Chang-Ming Dong and Mingsheng Chen
Polymer Reviews, 2024, 64, 528
DOI: 10.1080/15583724.2023.2281462

Accelerated Preparation of Polypeptides and Related Hybrid Materials from a Disintegrable Initiator Array with Masked Carbenium Precursors
Zehong Cheng, Jing Guo, Jia Pan, Ying Liu, Huan Wei, Jishan Li, Song Liu, Yuanyuan Hu and Yugang Bai
Chem. Mater., 2022, 34, 10732
DOI: 10.1021/acs.chemmater.2c02913

Spotting Trends in Organocatalyzed and Other Organomediated (De)polymerizations and Polymer Functionalizations
María Valle, Marta Ximenis, Xabier Lopez de Pariza, Julian M. W. Chan and Haritz Sardon
Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202203043

Polymerization of N-Carboxyanhydride in Cosolvents: The Balance between the Polymerization Rate and Molecular Weight Control
Qinyuan Li, Yingjia Lan, Wanying Wang, Guonan Ji, Xiaohong Li and Ziyuan Song
Macromolecules, 2023, 56, 7023
DOI: 10.1021/acs.macromol.3c00704

Nanoengineered polypeptides from tetraphenylethylene-functionalized N-carboxyanhydride: Synthesis, self-assembly and intrinsic aggregation-induced emission
Xu Wang, Zihao Zhao, Tianrui Xue, Zhengzhong Tan, Ziyuan Song, Shiqi Wei, Yang Bo, Ying Wang and Jianjun Cheng
Progress in Natural Science: Materials International, 2021, 31, 541
DOI: 10.1016/j.pnsc.2021.03.003

Polypept(o)ide-based bactericides: weapons against antibiotic-resistant bacterial infections
Maochao Zheng, Xiaolei Wu, Chao Lu, Wancong Zhang, Shijie Tang, Ying Luo and Daojun Liu
Materials Today Chemistry, 2023, 27, 101270
DOI: 10.1016/j.mtchem.2022.101270

Secondary Structure-Governed Polypeptide Cross-Linked Polymeric Hydrogels
Chongyi Chen, Jun Lan, Yuanchao Li, Dongran Liang, Xiuquan Ni and Qiao Liu
Chem. Mater., 2020, 32, 1153
DOI: 10.1021/acs.chemmater.9b04160

Designing peptide nanoparticles for efficient brain delivery
Aroa Duro-Castano, Diana Moreira Leite, Joe Forth, Yangwei Deng, Diana Matias, Carlos Noble Jesus and Giuseppe Battaglia
Advanced Drug Delivery Reviews, 2020, 160, 52
DOI: 10.1016/j.addr.2020.10.001

Controlled Synthesis of Crystalline and Helical N-Alkyl Poly(l-alanine)
Wenxiao Liu, Xuehua Deng, Yutong Dong, Sunting Xuan and Zhengbiao Zhang
Macromolecules, 2024, 57, 7031
DOI: 10.1021/acs.macromol.4c01121

Synthesis of poly(thiourethane-alt-thioester) by alternating ring-opening copolymerization of N-thiocarboxyanhydrides and episulfides
Wei Xiong, Tianjun Yue, Haiwang Lai, Chunyan Lyu, Weimin Ren and Hua Lu
Sci. China Chem., 2024, 67, 3091
DOI: 10.1007/s11426-024-2051-x

Out of equilibrium coil-helix transition driven by chemical fuels
Wang Zeng, Che Fan, Xupu Xing, Hao Cheng, Huimin Fu, Bingxu Ma, Ziqiong Yang, Rui Zhang and Wei Zhang
Giant, 2021, 7, 100067
DOI: 10.1016/j.giant.2021.100067

Design of Stimuli‐Responsive Peptides and Proteins
Yang Li, Guangze Yang, Lukas Gerstweiler, San H. Thang and Chun‐Xia Zhao
Adv Funct Materials, 2023, 33
DOI: 10.1002/adfm.202210387

An Inspection into Multifarious Ways to Synthesize Poly(Amino Acid)s
Botuo Zheng, Tianwen Bai, Xinfeng Tao and Jun Ling
Macromol. Rapid Commun., 2021, 42
DOI: 10.1002/marc.202100453

Modulation of Conformational Transition of Polypeptides under Slightly Acidic Environment†
Jie Li, Jiajie Zhang, Qi Long, Weisheng Guo and Menghua Xiong
Chin. J. Chem., 2022, 40, 2981
DOI: 10.1002/cjoc.202200483

Conformation-Switchable Polypeptides as Molecular Gates for Controllable Drug Release
Chenglong Ge, Jianyin He, Mudan Gan, Yu Qian, Junliang Zhu, Fan Wu, Ziyuan Song and Lichen Yin
Biomacromolecules, 2024, 25, 3373
DOI: 10.1021/acs.biomac.4c00024

Recent Progress of pH-Responsive Peptides, Polypeptides, and Their Supramolecular Assemblies for Biomedical Applications
Mingxuan Hou and Shiyong Liu
Biomacromolecules, 2024, 25, 5402
DOI: 10.1021/acs.biomac.4c00688

Effect of Confinement Geometry on Semiflexible Linear Polymer Conformations: A Computational and Simulation Study
Xiao‐lin Zhou, Xiao Zhang and Yu‐ping Liu
Macro Chemistry & Physics, 2025, 226
DOI: 10.1002/macp.202500288

Polypeptide-based materials prepared by ring-opening polymerisation of anionic-based α-amino acid N-carboxyanhydrides: A platform for delivery of bioactive-compounds
Ernesto Tinajero-Díaz, Scott D. Kimmins, Zaira-Yunuen García-Carvajal and Antxon Martínez de Ilarduya
Reactive and Functional Polymers, 2021, 168, 105040
DOI: 10.1016/j.reactfunctpolym.2021.105040

Synthetic Mimics of Antimicrobial Peptides for the Targeted Therapy of Multidrug‐Resistant Bacterial Infection
Chenyu Gong, Junjie Sun, Yan Xiao, Xue Qu and Meidong Lang
Adv Healthcare Materials, 2021, 10
DOI: 10.1002/adhm.202101244

Helical Nonfouling Polypeptides for Biomedical Applications
Chong Zhang and Hua Lu
Chin J Polym Sci, 2022, 40, 433
DOI: 10.1007/s10118-022-2688-2

Effects of Secondary Structures and pH on the Self-Assembly of Poly(ethylene glycol)-b-polytyrosine
Caixia Jiang, Chonghao Zhao, Peng Xu, Qipeng Song, Xinfeng Tao and Shaoliang Lin
Biomacromolecules, 2024, 25, 5028
DOI: 10.1021/acs.biomac.4c00437

Recent Advances and Future Perspectives of Synthetic Polypeptides from N-Carboxyanhydrides
Ziyuan Song, Zhengzhong Tan and Jianjun Cheng
Macromolecules, 2019, 52, 8521
DOI: 10.1021/acs.macromol.9b01450

Ultrasmall Zwitterionic Polypeptide-Coordinated Nanohybrids for Highly Efficient Cancer Photothermal Ferrotherapy
Chang Du, Lei Zhou, Jiwen Qian, Meng He, Zhi-Gang Zhang, Chuanliang Feng, Yongming Zhang, Rong Zhang and Chang-Ming Dong
ACS Appl. Mater. Interfaces, 2021, 13, 44002
DOI: 10.1021/acsami.1c11381

Template‐assisted Flexible‐to‐rigid Transition of Peptides in Head‐to‐tail Self‐polymerization Enables Sequence‐controllable and Post‐modifiable Peptide Nanofibers
Tianzi Chen, Yin Liu, Zhanshan Gao, Yue Gao, Haijin Chen, Haonan Ye, Qiuhao Luo, Kefeng Wang and Dongdong Wu
Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202415809

Recent advances in the molecular engineering of synthetic polypeptides: Design, synthesis, functionality, and biological applications
Prabir Maity, Arjun Singh Bisht, Ankita Kumari and Raj Kumar Roy
Progress in Polymer Science, 2025, 171, 102040
DOI: 10.1016/j.progpolymsci.2025.102040

Construction of shape memorable imprinted cavities for protein recognition using oligo-l-lysine-based peptide crosslinker
Sha Wang, Wenjun Lu, Yafei Wang, Ying Guan and Yongjun Zhang
Journal of Colloid and Interface Science, 2021, 595, 118
DOI: 10.1016/j.jcis.2021.03.123

Rigid, α-Helical Polypeptide Nanoprobes with Thermally Activated Delayed Fluorescence for Time-Resolved, High-Contrast Bioimaging
Yang Chu, Xiaoxiong Jin, Guonan Ji, Pengfei Li, Shanshan Xiao, Wanying Wang and Ziyuan Song
ACS Nano, 2025, 19, 680
DOI: 10.1021/acsnano.4c11719

Superfast and Water‐Insensitive Polymerization on α‐Amino Acid N‐Carboxyanhydrides to Prepare Polypeptides Using Tetraalkylammonium Carboxylate as the Initiator
Yueming Wu, Kang Chen, Xue Wu, Longqiang Liu, Weiwei Zhang, Yun Ding, Shiqi Liu, Min Zhou, Ning Shao, Zhemin Ji, Jiacheng Chen, Minghui Zhu and Runhui Liu
Angew Chem Int Ed, 2021, 60, 26063
DOI: 10.1002/anie.202103540

Multiblock Copolymers toward Segmentation-Driven Morphological Transition
Yi Zheng, Chuang Weng, Cheng Cheng, Jinling Zhao, Rui Yang, Qin Zhang, Mingming Ding, Hong Tan and Qiang Fu
Macromolecules, 2020, 53, 5992
DOI: 10.1021/acs.macromol.0c00374

Regulation of the cellular uptake of nanoparticles by the orientation of helical polypeptides
Chong Zhang, Jianhua Lu, Falin Tian, Lindong Li, Yingqin Hou, Yaoyi Wang, Lingdong Sun, Xinghua Shi and Hua Lu
Nano Res., 2019, 12, 889
DOI: 10.1007/s12274-019-2319-6

Self-Assembling Oligo(2-oxazoline) Organogelators for the Encapsulation and Slow Release of Bioactive Volatiles
Yichao Lv, Yuanjiang Zhao, Yuhang Liu, Zhuxian Zhou, Youqing Shen and Liming Jiang
ACS Omega, 2022, 7, 27523
DOI: 10.1021/acsomega.2c02905

ROS-Responsive Selenopolypeptide Micelles: Preparation, Characterization, and Controlled Drug Release
Chenglong Ge, Junliang Zhu, Guangqi Wu, Huan Ye, Hua Lu and Lichen Yin
Biomacromolecules, 2022, 23, 2647
DOI: 10.1021/acs.biomac.2c00399

Tunable Aggregation-Induced Emission Fluorophore with the Assistance of the Self-Assembly of Block Copolymers by Controlling the Morphology and Secondary Conformation for Bioimaging
Sifan Ji, Min Lin, Zenghao Li, Lili Xu, Xiaohui Fu, Guosong Chen, Zhibo Li and Jing Sun
Biomacromolecules, 2022, 23, 798
DOI: 10.1021/acs.biomac.1c01220

Ordered Conformation‐Regulated Vesicular Membrane Permeability
Yi Zheng, Zuojie Wang, Zifen Li, Hang Liu, Jing Wei, Chuan Peng, Yeqiang Zhou, Jianshu Li, Qiang Fu, Hong Tan and Mingming Ding
Angewandte Chemie, 2021, 133, 22703
DOI: 10.1002/ange.202109637

Rational Construction of Protein-Mimetic Nano-Switch Systems Based on Secondary Structure Transitions of Synthetic Polypeptides
Chenglong Ge, Junliang Zhu, Huan Ye, Yuansong Wei, Yuheng Lei, Renxiang Zhou, Ziyuan Song and Lichen Yin
J. Am. Chem. Soc., 2023, 145, 11206
DOI: 10.1021/jacs.3c01156

Enzymatic synthesis of polypeptides in natural deep eutectic solvents
Ángel Hernández-Alonso, Vanessa Pérez-García, Jared López-Medina, Luis Cedeño-Caero, Jonathan Trapala, Carmina Montiel, Ismael Bustos-Jaimes and Miquel Gimeno
J Polym Res, 2023, 30
DOI: 10.1007/s10965-023-03808-1

A bispecific glycopeptide spatiotemporally regulates tumor microenvironment for inhibiting bladder cancer recurrence
Hong-Wei An, Da-Yong Hou, Jia Yang, Zi-Qi Wang, Man-Di Wang, Rui Zheng, Ni-Yuan Zhang, Xing-Jie Hu, Zhi-Jia Wang, Lu Wang, Di Liu, Jun-Feng Hao, Wanhai Xu, Yuliang Zhao and Hao Wang
Sci. Adv., 2023, 9
DOI: 10.1126/sciadv.abq8225

Thermomechanical Properties of Solid “Liquid Crystalline” Films from Hot-Pressed Synthetic Polypeptides of Various Macromolecular Architectures
Stephen R. Ekatan, Tianrui Xue, Ziyuan Song, Tianjian Yang, Dennis Ndaya, Montgomery T. Shaw, Jianjun Cheng and Yao Lin
Macromolecules, 2024, 57, 2008
DOI: 10.1021/acs.macromol.3c02005

Molecularly Imprinted Polymer with High Capacity and Selectivity for Separation of Bovine Serum Albumin
Meiyu Zhang, Yafei Wang, Keling Hu, Yaojing Zhang, Shun Liu, Zhuo Zhao, Lei Zou and Yongjun Zhang
ACS Appl. Polym. Mater., 2023, 5, 9751
DOI: 10.1021/acsapm.3c01370

Protease-catalyzed synthesis of α-poly-L-Lysine and amphiphilic poly(L-lysine-co-L-phenylalanine) in a neat non-toxic organic solvent
Ángel Espinoza-González, Carmen Hernández-Valencia, Luis Cedeño-Caero, Roberto Sánchez-Sánchez, Carmina Montiel and Miquel Gimeno
Bioprocess Biosyst Eng, 2023, 46, 515
DOI: 10.1007/s00449-022-02836-3

Reduction of a disulfide-constrained oligo-glutamate peptide triggers self-assembly of β2-type amyloid fibrils with the chiroptical properties determined by supramolecular chirality
Robert Dec, Marcin Guza and Wojciech Dzwolak
International Journal of Biological Macromolecules, 2020, 162, 866
DOI: 10.1016/j.ijbiomac.2020.06.221

Advance in the Polymerization Strategy for the Synthesis of β‐Peptides and β‐Peptoids
Ximian Xiao, Min Zhou, Zihao Cong, Jingcheng Zou and Runhui Liu
ChemBioChem, 2023, 24
DOI: 10.1002/cbic.202200368

Aqueously dispersed homopolypeptide nanotoroids with tunable circularly polarized luminescence
Yuanpeng Ye, Xinke Hu, Dong Yang, Qianxi Gu, Shangning Liu, Jinhui Jiang, Guofeng Liu and Jianzhong Du
Chinese Chemical Letters, 2025, 111844
DOI: 10.1016/j.cclet.2025.111844

On the origin of the low immunogenicity and biosafety of a neutral α-helical polypeptide as an alternative to polyethylene glycol
Jialing Sun, Junyi Chen, Yiming Sun, Yingqin Hou, Zhibo Liu and Hua Lu
Bioactive Materials, 2024, 32, 333
DOI: 10.1016/j.bioactmat.2023.10.011

Optically Active Polymers with Cationic Units Connected through Neutral Spacers: Helical Conformation and Chirality Transfer to External Molecules
Yuting Wang, Nino Zavradashvili, Yue Wang, Adriana Pietropaolo, Zhiyi Song, Masayoshi Bando, Ramaz Katsarava and Tamaki Nakano
Macromolecules, 2020, 53, 9916
DOI: 10.1021/acs.macromol.0c02199

Influences of chain length and conformation of guanidinylated linear synthetic polypeptides on nuclear delivery of siRNA with potential application in transcriptional gene silencing
Suifei Li, Junyang Zhong, Yunxiao Ma, Chengfeng Yue, Wenxia Lv, Guodong Ye, Xiumei Tian, Xin Li, Yugang Huang and Lingran Du
International Journal of Biological Macromolecules, 2025, 308, 142743
DOI: 10.1016/j.ijbiomac.2025.142743

Photoallosteric Polymersomes toward On‐Demand Drug Delivery and Multimodal Cancer Immunotherapy
Yi Zheng, Yang Liu, Zhongchao Wu, Chuan Peng, Zuojie Wang, Jingyue Yan, Yue Yan, Zifen Li, Congcong Liu, Jianxin Xue, Hong Tan, Qiang Fu and Mingming Ding
Advanced Materials, 2023, 35
DOI: 10.1002/adma.202210986

Modeling and Designing Particle-Regulated Amyloid-like Assembly of Synthetic Polypeptides in Aqueous Solution
Tianjian Yang, Kyle Benson, Hailin Fu, Tianrui Xue, Ziyuan Song, Hanyi Duan, Hongwei Xia, Ankarao Kalluri, Jie He, Jianjun Cheng, Challa V. Kumar and Yao Lin
Biomacromolecules, 2022, 23, 196
DOI: 10.1021/acs.biomac.1c01230

Crucial Impact of Residue Chirality on the Gelation Process and Biodegradability of Thermoresponsive Polypeptide Hydrogels
Dong Li, Dan Zhao, Chaoliang He and Xuesi Chen
Biomacromolecules, 2021, 22, 3992
DOI: 10.1021/acs.biomac.1c00785

Template‐assisted Flexible‐to‐rigid Transition of Peptides in Head‐to‐tail Self‐polymerization Enables Sequence‐controllable and Post‐modifiable Peptide Nanofibers
Tianzi Chen, Yin Liu, Zhanshan Gao, Yue Gao, Haijin Chen, Haonan Ye, Qiuhao Luo, Kefeng Wang and Dongdong Wu
Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202415809

Efficient Preparation of Polypeptides through Accelerated Polymerization of N-Carboxyanhydrides in Continuous Flow
Yu-Ke Qian, Shao-Bo Feng and Zi-Yuan Song
Chin J Polym Sci, 2025
DOI: 10.1007/s10118-025-3441-4

Protein‐Inspired Polymers with Metal‐Site‐Regulated Ordered Conformations
Hang Liu, Yeqiang Zhou, Yang Liu, Zuojie Wang, Yi Zheng, Chuan Peng, Meng Tian, Qin Zhang, Jianshu Li, Hong Tan, Qiang Fu and Mingming Ding
Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202213000

Target‐Triggered Self‐Assembly of Peptides with Silver Nanoparticles for Electrochemical Biosensing
Yuying Pan, Yujing Zeng, Jiazhu Pu, Qianxi Zhou, Sha Zhu and Genxi Li
Chemistry A European J, 2025
DOI: 10.1002/chem.202502408

Synthesis and Self-Assembly Behavior of Chlorophyll Derivatives for Ratiometric Photoacoustic Signal Optimization
Jin Zhou, Zi-Jun Gao, Jun-Quan Cai, Li-Li Li and Hao Wang
Langmuir, 2020, 36, 1559
DOI: 10.1021/acs.langmuir.9b03652