Five-membered heterocycles as promising platforms for molecular logic gate construction

Alexander Ciupa

RSC Adv., 2025, 15, 10565
DOI: 10.1039/D5RA00749F

Recent advances in continuous-flow organocatalysis for process intensification

Carmela De Risi, Olga Bortolini, Arianna Brandolese, Graziano Di Carmine, Daniele Ragno and Alessandro Massi

React. Chem. Eng., 2020, 5, 1017
DOI: 10.1039/D0RE00076K

Integration of segmented microflow chemistry and online HPLC/MS analysis on a microfluidic chip system enabling enantioselective analyses at the nanoliter scale

Sebastian K. Piendl, Thomas Schönfelder, Matthias Polack, Laura Weigelt, Till van der Zwaag, Thorsten Teutenberg, Erik Beckert and Detlev Belder

Lab Chip, 2021, 21, 2614
DOI: 10.1039/D1LC00078K

Continuous flow chemistry: where are we now? Recent applications, challenges and limitations

Faith M. Akwi and Paul Watts

Chem. Commun., 2018, 54, 13894
DOI: 10.1039/C8CC07427E

Why microfluidics? Merits and trends in chemical synthesis

Yong Liu and Xingyu Jiang

Lab Chip, 2017, 17, 3960
DOI: 10.1039/C7LC00627F

Microfluidics and surface-enhanced Raman spectroscopy, a win–win combination?

Rajapandiyan Panneerselvam, Hasan Sadat, Eva-Maria Höhn, Anish Das, Hemanth Noothalapati and Detlev Belder

Lab Chip, 2022, 22, 665
DOI: 10.1039/D1LC01097B

An all thiol–ene microchip for solid phase extraction featuring an in situ polymerized monolith and integrated 3D replica-molded emitter for direct electrospray mass spectrometry

Alexander Jönsson, Josiane P. Lafleur, Drago Sticker and Jörg P. Kutter

Anal. Methods, 2018, 10, 2854
DOI: 10.1039/C8AY00646F

A novel microfluidic microelectrode chip for a significantly enhanced monitoring of NPY-receptor activation in live mode

Franziska D. Zitzmann, Heinz-Georg Jahnke, Felix Nitschke, Annette G. Beck-Sickinger, Bernd Abel, Detlev Belder and Andrea A. Robitzki

Lab Chip, 2017, 17, 4294
DOI: 10.1039/C7LC00754J

Der Chromatograph auf einem Glasplättchen

Detlev Belder and Josef Heiland

Nachr Chem, 2018, 66, 1062
DOI: 10.1002/nadc.20184076064

Particle-based liquid chromatographic separations in microfluidic devices - A review

Adam Kecskemeti and Attila Gaspar

Analytica Chimica Acta, 2018, 1021, 1
DOI: 10.1016/j.aca.2018.01.064

Rapid detection of glycosylated hemoglobin levels by a microchip liquid chromatography system in gradient elution mode

Dezhao Jiao, Ruirong Zhang, Hantian Zhang, Haoquan Ma, Xiaorui Zhang, Xiaoguang Fan and Honglong Chang

Analytica Chimica Acta, 2024, 1288, 342186
DOI: 10.1016/j.aca.2023.342186

High-Throughput and Ultrafast Liquid Chromatography

Alexander S. Kaplitz, Glenn A. Kresge, Benjamin Selover, Leah Horvat, Edward G. Franklin, Justin M. Godinho, Kaitlin M. Grinias, Samuel W. Foster, Joshua J. Davis and James P. Grinias

Anal. Chem., 2020, 92, 67
DOI: 10.1021/acs.analchem.9b04713

Simple 3D printed stainless steel microreactors for online mass spectrometric analysis

Gianmario Scotti, Sofia M.E. Nilsson, Ville-Pekka Matilainen, Markus Haapala, Gustav Boije af Gennäs, Jari Yli-Kauhaluoma, Antti Salminen and Tapio Kotiaho

Heliyon, 2019, 5, e02002
DOI: 10.1016/j.heliyon.2019.e02002

Recent progress in lab-on-a-chip for pharmaceutical analysis and pharmacological/toxicological test

Yongjian Ai, Feng Zhang, Chenlong Wang, Ruoxiao Xie and Qionglin Liang

TrAC Trends in Analytical Chemistry, 2019, 117, 215
DOI: 10.1016/j.trac.2019.06.026

Seamless Combination of High-Pressure Chip-HPLC and Droplet Microfluidics on an Integrated Microfluidic Glass Chip

Renata F. Gerhardt, Andrea J. Peretzki, Sebastian K. Piendl and Detlev Belder

Anal. Chem., 2017, 89, 13030
DOI: 10.1021/acs.analchem.7b04331

The Molecular Industrial Revolution: Automated Synthesis of Small Molecules

Melanie Trobe and Martin D. Burke

Angew Chem Int Ed, 2018, 57, 4192
DOI: 10.1002/anie.201710482

Chip-based ion chromatography (chip-IC) with a sensitive five-electrode conductivity detector for the simultaneous detection of multiple ions in drinking water

Xiaoping Li and Honglong Chang

Microsyst Nanoeng, 2020, 6
DOI: 10.1038/s41378-020-0175-x

Multiple Heart-Cutting Two-Dimensional Chip-HPLC Combined with Deep-UV Fluorescence and Mass Spectrometric Detection

Sebastian K. Piendl, David Geissler, Laura Weigelt and Detlev Belder

Anal. Chem., 2020, 92, 3795
DOI: 10.1021/acs.analchem.9b05206

Fabricating an Electrospray Ionization Chip Based on Induced Polarization and Liquid Splitting

Lvhan Zhou, Qian Zhang, Xiangchun Xu, Xinming Huo, Qian Zhou, Xiaohao Wang and Quan Yu

Micromachines, 2021, 12, 1034
DOI: 10.3390/mi12091034

Process analytical technologies and self-optimization algorithms in automated pharmaceutical continuous manufacturing

Peiwen Liu, Hui Jin, Yan Chen, Derong Wang, Haohui Yan, Mingzhao Wu, Fang Zhao and Weiping Zhu

Chinese Chemical Letters, 2024, 35, 108877
DOI: 10.1016/j.cclet.2023.108877

Heterogeneous Catalysis under Continuous Flow Conditions

Ashu Gupta, Radhika Gupta, Gunjan Arora, Priya Yadav and Rakesh Kumar Sharma

COC, 2023, 27, 1090
DOI: 10.2174/0113852728268688230921105908

High-efficiency and safe synthesis of tonalid via two Friedel-Crafts reactions in continuous-flow microreactors

Yang Han, Yuanyuan Liu, Shiwei Wang, Xuehui Ge, Xiaoda Wang and Ting Qiu

Chinese Journal of Chemical Engineering, 2022, 52, 126
DOI: 10.1016/j.cjche.2021.09.028

Research Progress of Microfluidic Technique in Synthesis of Micro/Nano Materials

Jia-Min Lu, Hui-Feng Wang, Jian-Zhang Pan and Qun Fang

Acta Chimica Sinica, 2021, 79, 809
DOI: 10.6023/A21030086

An Integrated Lab‐on‐a‐chip Approach to Study Heterogeneous Enantioselective Catalysts at the Microscale

Rico Warias, Anna Zaghi, Josef J. Heiland, Sebastian K. Piendl, Kerry Gilmore, Peter H. Seeberger, Alessandro Massi and Detlev Belder

ChemCatChem, 2018, 10, 5382
DOI: 10.1002/cctc.201801637

Micro: An International Open Access Journal for All of Microscale and Nanoscale Science

Eiichi Tamiya

Micro, 2021, 1, 1
DOI: 10.3390/micro1010001

A Visible‐Light‐Powered Polymerization Method for the Immobilization of Enantioselective Organocatalysts into Microreactors

Rico Warias, Daniele Ragno, Alessandro Massi and Detlev Belder

Chemistry A European J, 2020, 26, 13152
DOI: 10.1002/chem.202002063

Liquid Wells as Self‐Healing, Functional Analogues to Solid Vessels

Johannes M. Scheiger, Mariia A. Kuzina, Michael Eigenbrod, Yanchen Wu, Fei Wang, Stefan Heißler, Steffen Hardt, Britta Nestler and Pavel A. Levkin

Advanced Materials, 2021, 33
DOI: 10.1002/adma.202100117

In situ monitoring of photocatalyzed isomerization reactions on a microchip flow reactor by IR-MALDI ion mobility spectrometry

Chris Prüfert, Raphael David Urban, Tillmann Georg Fischer, José Villatoro, Daniel Riebe, Toralf Beitz, Detlev Belder, Kirsten Zeitler and Hans-Gerd Löhmannsröben

Anal Bioanal Chem, 2020, 412, 7899
DOI: 10.1007/s00216-020-02923-y

Unveiling Organocatalysts Action – Investigating Immobilized Catalysts at Steady‐State Operation via Lab‐on‐a‐Chip Technology

Hannes Westphal, Rico Warias, Holger Becker, Matthias Spanka, Daniele Ragno, Roger Gläser, Christoph Schneider, Alessandro Massi and Detlev Belder

ChemCatChem, 2021, 13, 5089
DOI: 10.1002/cctc.202101148

Temperature Gradient Elution and Superheated Eluents in Chip-HPLC

Josef J. Heiland, Carsten Lotter, Volkmar Stein, Laura Mauritz and Detlev Belder

Anal. Chem., 2017, 89, 3266
DOI: 10.1021/acs.analchem.7b00142

3D Micropatterned All‐Flexible Microfluidic Platform for Microwave‐Assisted Flow Organic Synthesis

Deniz Hur, Mehmet G. Say, Sibel E. Diltemiz, Fatma Duman, Arzu Ersöz and Rıdvan Say

ChemPlusChem, 2018, 83, 42
DOI: 10.1002/cplu.201700440

Integration of Impedimetric Sensors for In Situ Electrochemical Impedance Spectroscopy in Free-Flow Electrophoresis Applications in Lab-on-Chip Systems

Tobias Haensch, Franziska D. Zitzmann, Heinz-Georg Jahnke, Maximilian E. Blaha, Erik Paternoga, Kirsten Zeitler, Detlev Belder and Andrea A. Robitzki

ACS Sens., 2022, 7, 3906
DOI: 10.1021/acssensors.2c01938

Joining Microfluidics with Infrared Photodissociation: Online Monitoring of Isomeric Flow-Reaction Intermediates

Maik Pahl, Martin Mayer, Maximilian Schneider, Detlev Belder and Knut R. Asmis

Anal. Chem., 2019, 91, 3199
DOI: 10.1021/acs.analchem.8b05532

Die molekulare industrielle Revolution: zur automatisierten Synthese organischer Verbindungen

Melanie Trobe and Martin D. Burke

Angewandte Chemie, 2018, 130, 4266
DOI: 10.1002/ange.201710482

2D in Seconds: Coupling of Chip-HPLC with Ion Mobility Spectrometry

Sebastian K. Piendl, Christian-Robert Raddatz, Nora T. Hartner, Christian Thoben, Rico Warias, Stefan Zimmermann and Detlev Belder

Anal. Chem., 2019, 91, 7613
DOI: 10.1021/acs.analchem.9b00302

Process analytical technology and its recent applications for asymmetric synthesis

Nicole M. Ralbovsky and Joseph P. Smith

Talanta, 2023, 252, 123787
DOI: 10.1016/j.talanta.2022.123787

Supercritical-Fluid Chromatography On-Chip with Two-Photon-Excited-Fluorescence Detection for High-Speed Chiral Separations

Josef J. Heiland, David Geissler, Sebastian K. Piendl, Rico Warias and Detlev Belder

Anal. Chem., 2019, 91, 6134
DOI: 10.1021/acs.analchem.9b00726