Issue 37, 2022

Enhanced detection of ascorbic acid with cascaded fluorescence recovery of a dual-nanoquencher system

Abstract

An innovative strategy with target-triggered cascade fluorescence recovery of a dual-nanoquencher system was developed to detect ascorbic acid (AA). Herein, manganese dioxide (MnO2) nanosheets and gold nanoparticles (AuNPs) were used as nanoquenchers simultaneously. Owing to their synergistic effects, the fluorescence of 2,3-diaminophenazine (DAP) was decreased efficiently, thus minimizing the background fluorescence. The introduction of AA triggered the decomposition of MnO2 into Mn2+, which induced the aggregation of AuNPs. Both the decomposed MnO2 and aggregated AuNPs possess weak quenching abilities towards DAP. Such a cascade amplification strategy enhanced the detection sensitivity for AA with a LOD as low as 6.7 nM, which was two orders of magnitude lower than that of MnO2-based fluorescence assay. Furthermore, this amplification strategy was successfully applied to detect AA in food samples.

Graphical abstract: Enhanced detection of ascorbic acid with cascaded fluorescence recovery of a dual-nanoquencher system

Supplementary files

Article information

Article type
Paper
Submitted
24 Jan 2022
Accepted
11 Pha 2022
First published
12 Pha 2022

Anal. Methods, 2022,14, 3632-3637

Enhanced detection of ascorbic acid with cascaded fluorescence recovery of a dual-nanoquencher system

Z. Liu, Y. Zuo, Y. Xia, J. Sun and S. Zhu, Anal. Methods, 2022, 14, 3632 DOI: 10.1039/D2AY01019D

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