Issue 4, 2020

One-step in vivo metabolic labeling as a theranostic approach for overcoming drug-resistant bacterial infections

Abstract

A bacterial metabolic probe combining D-alanine and a photosensitizer with aggregation-induced emission (AIE) has been developed for in vivo light-up imaging of bacterial walls and efficient antibacterial therapy. This activatable probe could serve as a promising non-antibiotic tool for diagnosis and treatment of biofilms and intracellular bacteria, as well as multi-resistant bacterial infections.

Graphical abstract: One-step in vivo metabolic labeling as a theranostic approach for overcoming drug-resistant bacterial infections

Supplementary files

Article information

Article type
Communication
Submitted
22 Mph 2019
Accepted
03 Phe 2020
First published
08 Phe 2020

Mater. Horiz., 2020,7, 1138-1143

One-step in vivo metabolic labeling as a theranostic approach for overcoming drug-resistant bacterial infections

D. Mao, F. Hu, Kenry, G. Qi, S. Ji, W. Wu, D. Kong and B. Liu, Mater. Horiz., 2020, 7, 1138 DOI: 10.1039/C9MH01675A

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