Issue 16, 2019

Aryl C–H amination initiated by laccase-mediated oxidation of 4-phenylurazole

Abstract

A mild amination of aryl C–H has been developed using laccase as a green and sustainable catalyst, aerial O2 as the oxidant, with water being the only by-product. Various aromatic compounds including anilines, naphthols, quinolines and substituted benzenes can be aminated with 4-phenylurazole in yields up to 93%.

Graphical abstract: Aryl C–H amination initiated by laccase-mediated oxidation of 4-phenylurazole

Supplementary files

Article information

Article type
Communication
Submitted
18 Mot 2019
Accepted
12 Upu 2019
First published
12 Upu 2019

Catal. Sci. Technol., 2019,9, 4216-4221

Aryl C–H amination initiated by laccase-mediated oxidation of 4-phenylurazole

Y. Chen, G. Zhang, Y. He and Z. Guan, Catal. Sci. Technol., 2019, 9, 4216 DOI: 10.1039/C9CY00968J

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