Issue 14, 2016

An efficient synthesis of sulfonated quinoline diones by copper catalyzed sulfonylation of activated alkenes with sulfonylhydrazides

Abstract

A novel and highly efficient cascade synthesis of sulfonated quinoline dione derivatives from N-(2-cyanoaryl) methylacrylamides and sulfonylhydrazides in good yields is described. The reaction proceeds through radical addition, cyclization, and imine hydrolysis, in which one new C–C bond and one C[double bond, length as m-dash]O bond were formed.

Graphical abstract: An efficient synthesis of sulfonated quinoline diones by copper catalyzed sulfonylation of activated alkenes with sulfonylhydrazides

Supplementary files

Article information

Article type
Communication
Submitted
28 Tsh 2015
Accepted
19 Phe 2016
First published
22 Phe 2016

RSC Adv., 2016,6, 11754-11757

An efficient synthesis of sulfonated quinoline diones by copper catalyzed sulfonylation of activated alkenes with sulfonylhydrazides

S. Wang, X. Huang, Q. Wang, Z. Ge, X. Wang and R. Li, RSC Adv., 2016, 6, 11754 DOI: 10.1039/C5RA27878C

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