Issue 39, 2013
From the journal:

Chemical Communications

A disulfide-linked conjugate of ferrocenyl chalcone and silicon(iv) phthalocyanine as an activatable photosensitiser†‡

Janet T. F. Lau,a   Xiong-Jie Jiang,a   Dennis K. P. Nga  and  Pui-Chi Lo*a  

* Corresponding authors

a Department of Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong
E-mail: pclo@cuhk.edu.hk
Fax: +852 2603 5057

Abstract

A novel bis(ferrocenyl chalcone) silicon(IV) phthalocyanine has been prepared in which the disulfide linker can be cleaved by dithiothreitol. The separation of the ferrocenyl quencher and the phthalocyanine core greatly enhances the fluorescence emission, singlet oxygen production and in vitro photocytotoxicity.

Graphical abstract: A disulfide-linked conjugate of ferrocenyl chalcone and silicon(iv) phthalocyanine as an activatable photosensitiser

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Article information

DOI
https://doi.org/10.1039/C2CC37251G
Article type
Communication
Submitted
04 Mph 2012
Accepted
24 Mph 2012
First published
07 Pun 2012

Chem. Commun., 2013,49, 4274-4276

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A disulfide-linked conjugate of ferrocenyl chalcone and silicon(IV) phthalocyanine as an activatable photosensitiser

J. T. F. Lau, X. Jiang, D. K. P. Ng and P. Lo, Chem. Commun., 2013, 49, 4274 DOI: 10.1039/C2CC37251G

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