Dennis Larsen, Andreas Erichsen, Giorgia Masciotta, Sebastian Meier and Sophie R. Beeren
Chem. Commun., 2024,60, 2090-2093
DOI:
10.1039/D3CC05897B,
Communication
Large-ring cyclodextrins (CDs) are a comparatively unexplored family of macrocycles. We use high-resolution 1H–13C HSQC NMR experiments to resolve the anomeric signals of at least 13 different size CDs in a mixture. Using a single titration experiment, we can quantify the individual binding capabilites of these structurally-related hosts, avoiding the need for cumbersome isolation.
