Issue 60, 2016

Atom-economic dehydrogenative amide synthesis via ruthenium catalysis

Abstract

Recently, a class of dehydrogenative transformations for amide bond formation have been developed. These transformations are atom-economic and environmentally-benign processes with their respective starting materials of alcohols and amines, aldehydes and amines, as well as symmetrical esters and amines, showing a promising prospect for applications. These unique protocols have been reported using various ruthenium-based catalytic systems. However, challenges still exist in this area. For example, existing catalytic systems usually suffer from low efficiency, high catalyst loading, and lack of structural diversity.

Graphical abstract: Atom-economic dehydrogenative amide synthesis via ruthenium catalysis

Article information

Article type
Review Article
Submitted
25 Mme 2016
Accepted
01 Jan 2016
First published
03 Jan 2016

RSC Adv., 2016,6, 55599-55607

Atom-economic dehydrogenative amide synthesis via ruthenium catalysis

C. Chen, F. Verpoort and Q. Wu, RSC Adv., 2016, 6, 55599 DOI: 10.1039/C6RA10643A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements