Issue 40, 2014
From the journal:

Chemical Communications

A fluorogenic probe for recognizing 5-hydroxylysine inspired by serine/threonine ligation†

Chun Ling Tung,‡a   Hiu Yung Lam,‡a   Jianchao Xua  and  Xuechen Li*a  

* Corresponding authors

a Department of Chemistry, The University of Hong Kong, Hong Kong, P. R. China
E-mail: xuechenl@hku.hk
Fax: +86 852 28571586

Abstract

The 5-lysyl-hydroxylation has been found among protein post-translational modifications. In this report, we have devised a fluorescence turn-on probe which allows for selectively recognizing 5-hydroxylysine-containing peptides.

Graphical abstract: A fluorogenic probe for recognizing 5-hydroxylysine inspired by serine/threonine ligation

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Article information

DOI
https://doi.org/10.1039/C3CC47465H
Article type
Communication
Submitted
30 Leo 2013
Accepted
22 Mph 2013
First published
22 Mph 2013

Chem. Commun., 2014,50, 5298-5300

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A fluorogenic probe for recognizing 5-hydroxylysine inspired by serine/threonine ligation

C. L. Tung, H. Y. Lam, J. Xu and X. Li, Chem. Commun., 2014, 50, 5298 DOI: 10.1039/C3CC47465H

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