Themed collection Food & Function Review Articles 2024
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Recent advances in nanodelivery systems of resveratrol and their biomedical and food applications: a review
The recent advances of resveratrol nano delivery systems, the advantages and potential limitations, as well as their associated applications in biomedical and food.
Food Funct., 2024, Advance Article
https://doi.org/10.1039/D3FO03892K
A systematic review and meta-analysis of randomized controlled trials: effects of mediterranean diet and low-fat diet on liver enzymes and liver fat content of NAFLD
From the RCTs, the MD and LFD have similar effects on improving liver enzymes and liver fat content in NAFLD for the short term.
Food Funct., 2024,15, 8248-8257
https://doi.org/10.1039/D4FO01461H
The effects of caffeine on pancreatic diseases: the known and possible mechanisms
Caffeine is a common component of coffee, tea, soft drinks and energy drinks. This review summarized the recent studies about its effects on pancreatic diseases and related mechanisms.
Food Funct., 2024,15, 8238-8247
https://doi.org/10.1039/D4FO02994A
A review of the biological activities of lactoferrin: mechanisms and potential applications
This paper reviews the biological activities of lactoferrin.
Food Funct., 2024,15, 8182-8199
https://doi.org/10.1039/D4FO02083A
Association between dietary vitamin C intake/blood level and risk of digestive system cancer: a systematic review and meta-analysis of prospective studies
This study finds that vitamin C intake could significantly reduce the incidence of gastrointestinal cancers, especially OPE, gastric, and colon cancers, suggesting that the impact of vitamin C may be more crucial than previously predicted.
Food Funct., 2024,15, 8217-8237
https://doi.org/10.1039/D4FO00350K
The regulation of glucose and lipid metabolism through the interaction of dietary polyphenols and polysaccharides via the gut microbiota pathway
Interactions of polyphenols and polysaccharides regulate glycolipid metabolism through the gut microbiota, which is achieved through the regulation of metabolites, intestinal barrier function, and signaling pathways.
Food Funct., 2024,15, 8200-8216
https://doi.org/10.1039/D4FO00585F
Recent research on the physicochemical properties and biological activities of quinones and their practical applications: a comprehensive review
Food Funct., 2024, Accepted Manuscript
https://doi.org/10.1039/D4FO02600D
Let food be your medicine – dietary fiber
Dietary intake of the right amount of dietary fiber can reduce the risk of disease and safeguard human health.
Food Funct., 2024,15, 7733-7756
https://doi.org/10.1039/D3FO05641D
Effects of glyphosate exposure on intestinal microbiota, metabolism and microstructure: a systematic review
Effects of glyphosate exposure on gut.
Food Funct., 2024,15, 7757-7781
https://doi.org/10.1039/D4FO00660G
Insights into chemical components, health-promoting effects, and processing impact of golden chanterelle mushroom Cantharellus cibarius
Cantharellus cibarius (CC) is a edible mushroom with significant commercial potential due to its diverse components and bioactive functions.
Food Funct., 2024,15, 7696-7732
https://doi.org/10.1039/D4FO00891J
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.146/content/NewImages/open-access-icon-orange.png)
Biomarkers of food intake and their relevance to metabolic syndrome
To assess diet and the risk of metabolic syndrome, this review highlights food bioactives that are correlated with dietary intake. In addition, these bioactives have shown to impact systemic inflammation and oxidative stress, among other.
Food Funct., 2024,15, 7271-7304
https://doi.org/10.1039/D4FO00721B
An overview of 6-shogaol: new insights into its pharmacological properties and potential therapeutic activities
Ginger (Zingiber officinale Roscoe) has traditionally been used as a cooking spice and herbal medicine for treating nausea and vomiting.
Food Funct., 2024,15, 7252-7270
https://doi.org/10.1039/D3FO04753A
A systematic review of randomized controlled trials on the health effects of chocolate enriched/fortified/supplemented with functional components
Bioactive enriched/fortified/supplemented chocolate.
Food Funct., 2024,15, 6883-6899
https://doi.org/10.1039/D4FO01574F
The role of tetrahydrocurcumin in disease prevention and treatment
Tetrahydrocurcumin showed potential biological activities in neurologic, cardiovascular, respiratory, liver, metabolic, renal, skin and inflammatory diseases as well as cancer.
Food Funct., 2024,15, 6798-6824
https://doi.org/10.1039/D3FO05739A
Polyphenols in edible plant leaves: an overview of their occurrence and health properties
Edible plant leaves (EPLs) constitute a major renewable functional plant biomass available all year round, providing an essential source of polyphenols in the global diet.
Food Funct., 2024,15, 6847-6882
https://doi.org/10.1039/D4FO00509K
Comparative analysis of pectin and prebiotics on human microbiota modulation in early life stages and adults
The gut microbiota is essential in human health, influencing various physiological processes ranging from digestion and metabolism to immune function and mental health.
Food Funct., 2024,15, 6825-6846
https://doi.org/10.1039/D4FO01231C
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.146/content/NewImages/open-access-icon-orange.png)
Milk fat globule membrane and its polar lipids: reviewing preclinical and clinical trials on cognition
Scheme of the potential use of MFGM as a dietary supplement on both infant and adult health.
Food Funct., 2024,15, 6783-6797
https://doi.org/10.1039/D4FO00659C
Advances in the composition, efficacy, and mimicking of human milk phospholipids
Phospholipids are the essential components of human milk. To provide a more scientific feeding method for infants, infant formulas should be formulated to close the phospholipids of human milk by adjusting raw and auxiliary ingredients.
Food Funct., 2024,15, 6254-6273
https://doi.org/10.1039/D4FO00539B
Nutraceuticals and dietary supplements: balancing out the pros and cons
While the market is full of different dietary supplements, in most countries, legislation is clear and strict towards these products, with severe limitations on their health claims.
Food Funct., 2024,15, 6289-6303
https://doi.org/10.1039/D4FO01113A
Bioactive compounds and benefits of by-products of Amazon babassu oil production: potential for dietary supplement, biomedical and food applications
Babassu mesocarp flour is promising for application as biodegradable packaging and as an antioxidant for foods. Phytochemicals, antiparasitic and antibacterial activities and mesocarp flour were shown, but fungi and viruses can get more attention.
Food Funct., 2024,15, 6232-6253
https://doi.org/10.1039/D4FO01594K
Intestinal absorption of bioactive oligopeptides: paracellular transport and tight junction modulation
Bioactive oligopeptides have gained increasing attention due to their diverse physiological functions, and these can be transported into the vasculature via transcellular and paracellular pathways.
Food Funct., 2024,15, 6274-6288
https://doi.org/10.1039/D4FO00529E
Biological fate, functional properties, and design strategies for oral delivery systems for cinnamaldehyde
The bio-efficacy and delivery systems of cinnamaldehyde and the underlying mechanisms are summarized and evaluated.
Food Funct., 2024,15, 6217-6231
https://doi.org/10.1039/D4FO00614C
Bioactive compounds of peanut skin in prevention and adjunctive treatment of chronic non-communicable diseases
The global prevalence of cancer continues to increase, so does its mortality.
Food Funct., 2024,15, 6304-6323
https://doi.org/10.1039/D4FO00647J
Nisin-relevant antimicrobial peptides: synthesis strategies and applications
Food Funct., 2024, Accepted Manuscript
https://doi.org/10.1039/D3FO05619H
Breakfast skipping and risk of all-cause, cardiovascular and cancer mortality among adults: a systematic review and meta-analysis of prospective cohort studies
The present systematic review and meta-analysis was conducted to clarify the association between breakfast skipping and mortality outcomes.
Food Funct., 2024,15, 5703-5713
https://doi.org/10.1039/D3FO05705D
Anti-hyperuricemia bioactive peptides: a review on obtaining, activity, and mechanism of action
The present work outlines the methods for preparing peptides from food proteins and elucidate their efficacy and mechanisms in combating hyperuricemia, supported by in vitro and in vivo evidence.
Food Funct., 2024,15, 5714-5736
https://doi.org/10.1039/D4FO00760C
Emerging berries from the Brazilian Amazon and Atlantic Forest biomes: new sources of bioactive compounds with potential health benefits
Brazil has a broad geographic biodiversity spread across its six different biomes.
Food Funct., 2024,15, 5752-5784
https://doi.org/10.1039/D4FO00182F
The effectiveness of probiotics as an adjunct therapy in patients under mechanical ventilation: an umbrella systematic review and meta-analysis
Probiotics' role in critically ill, mechanically ventilated patients is unclear; therefore, we conducted an umbrella systematic review and meta-analysis to clarify probiotics' effects on clinical outcomes.
Food Funct., 2024,15, 5737-5751
https://doi.org/10.1039/D3FO04653B
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.146/content/NewImages/open-access-icon-orange.png)
Inhibitory effect of extracts from edible parts of nuts on α-amylase activity: a systematic review
The inhibitory effect of extracts from edible parts of nuts on α-amylase activity in vitro, including inhibition of human α-amylase by polyphenol-rich chestnut and almond skin extracts.
Food Funct., 2024,15, 5209-5223
https://doi.org/10.1039/D4FO00414K
Effects of a low FODMAP diet on the symptom management of patients with irritable bowel syndrome: a systematic umbrella review with the meta-analysis of clinical trials
Effect of low FODMAPs diet on symptoms of patients with irritable bowel syndrome.
Food Funct., 2024,15, 5195-5208
https://doi.org/10.1039/D3FO03717G
Unleashing the power of chlorogenic acid: exploring its potential in nutrition delivery and the food industry
In the contemporary era, heightened emphasis on health and safety has emerged as a paramount concern among individuals with food.
Food Funct., 2024,15, 4741-4762
https://doi.org/10.1039/D4FO00059E
Medicinal and edible polysaccharides from ancient plants: extraction, isolation, purification, structure, biological activity and market trends of sea buckthorn polysaccharides
Sea buckthorn (Hippophae L.), a well-known medicinal and edible plant, is known as the “king of VC”.
Food Funct., 2024,15, 4703-4723
https://doi.org/10.1039/D3FO04140A
Dietary fiber and polyphenols from whole grains: effects on the gut and health improvements
Cereal dietary fiber and polyphenols improve the intestinal environment and human health
Food Funct., 2024,15, 4682-4702
https://doi.org/10.1039/D4FO00715H
Olive oil intake and cardiovascular disease, cancer, and all-cause mortality: a systematic review and dose–response meta-analysis of prospective cohort studies
Higher olive oil intake was linked to a decreased risk of CVD and stroke incidence and CVD and all-cause mortality.
Food Funct., 2024,15, 4668-4681
https://doi.org/10.1039/D3FO05246J
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.146/content/NewImages/open-access-icon-orange.png)
Encapsulation of short-chain bioactive peptides (BAPs) for gastrointestinal delivery: a review
Majority of known bioactive peptides (BAPs) with antihypertensive, antidiabetic, antioxidant, among other activities, are short-chain aminoacid sequences (<10). To enhance their gastrointestinal bioavailability, BAPs are encapsulated, subject of our review.
Food Funct., 2024,15, 3959-3979
https://doi.org/10.1039/D3FO04195F
Effects of quercetin on the DNA methylation pattern in tumor therapy: an updated review
Quercetin reverses the expression of abnormal genes by regulating DNA methylation, and is an important regulator of gene transcription in tumorigenesis. The use of nanoscale delivery of quercetin increases its bioavailability in cancer therapy.
Food Funct., 2024,15, 3897-3907
https://doi.org/10.1039/D3FO03831A
Extraction, purification, structural modification, activities and application of polysaccharides from different parts of mulberry
Extraction, purification, structural modification, activities and application of polysaccharides from different parts of mulberry were analyzed and discussed.
Food Funct., 2024,15, 3939-3958
https://doi.org/10.1039/D3FO05747J
Effect of steviol glycosides as natural sweeteners on glucose metabolism in adult participants
SGs as safe natural sweeteners, may yield significant improvement in glucose metabolism in adult participants when compared with the control.
Food Funct., 2024,15, 3908-3919
https://doi.org/10.1039/D3FO04695H
Potential neuroprotective benefits of plant-based fermented foods in Alzheimer's disease: an update on preclinical evidence
Preclinical evidence suggests that plant-based fermented foods possess promising potential for the management of AD through modulation of oxidative stress, synaptotoxicity, neuroinflammation, tau hyperphosphorylation, and amyloidogenic pathways.
Food Funct., 2024,15, 3920-3938
https://doi.org/10.1039/D3FO03805J
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.146/content/NewImages/open-access-icon-orange.png)
Effectiveness of anthocyanin-containing foods and nutraceuticals in mitigating oxidative stress, inflammation, and cardiovascular health-related biomarkers: a systematic review of animal and human interventions
Cardiovascular diseases (CVDs) are a group of chronic health disorders prevalent worldwide that claim millions of lives yearly.
Food Funct., 2024,15, 3274-3299
https://doi.org/10.1039/D3FO04579J
Dietary intake of different ratios of ARA/DHA in early stages and its impact on infant development
This article systematically reviewed the proportion of ARA and DHA in breast milk and formula among regions and lactation periods, and their impact on infant development and health.
Food Funct., 2024,15, 3259-3273
https://doi.org/10.1039/D3FO04629J
Screening, separation and identification of metal-chelating peptides for nutritional, cosmetics and pharmaceutical applications
Metal-chelating peptides, which form metal–peptide coordination complexes with various metal ions, can be used as biofunctional ingredients notably to enhance human health and prevent diseases.
Food Funct., 2024,15, 3300-3326
https://doi.org/10.1039/D3FO05765H
Efficacy of oats in dyslipidemia: a systematic review and meta-analysis
Background: In recent years, oats’ effect on lowering serum cholesterol has been recognized.
Food Funct., 2024,15, 3232-3245
https://doi.org/10.1039/D3FO04394K
Structural characteristics and biological activities of polysaccharides from barley: a review
Structural characteristics and biological activities of polysaccharides from barley (Hordeum vulgare L).
Food Funct., 2024,15, 3246-3258
https://doi.org/10.1039/D3FO05793C
Mechanisms of probiotic modulation of ovarian sex hormone production and metabolism: a review
Effects of the brain, liver, pancreas, and fat on ovarian sex hormone production through the gut.
Food Funct., 2024,15, 2860-2878
https://doi.org/10.1039/D3FO04345B
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.146/content/NewImages/open-access-icon-orange.png)
Cell culture models for assessing the effects of bioactive compounds in common buckwheat (Fagopyrum esculentum): a systematic review
Systematic review of studies on the biological effect of common buckwheat supplementation on cellular models.
Food Funct., 2024,15, 2799-2813
https://doi.org/10.1039/D4FO00202D
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.146/content/NewImages/open-access-icon-orange.png)
(Poly)phenol-related gut metabotypes and human health: an update
(Poly)phenol metabotyping as a tool for tailored nutrition advice. Created with https://BioRender.com.
Food Funct., 2024,15, 2814-2835
https://doi.org/10.1039/D3FO04338J
A review of the world's salt reduction policies and strategies – preparing for the upcoming year 2025
Salt reduction initiatives, intertwined with national health, requires long-term and collaborative efforts among governments, food enterprises, public health experts, and the public. It is imperative to explore more effective methods for salt reduction to attain the global goal.
Food Funct., 2024,15, 2836-2859
https://doi.org/10.1039/D3FO03352J
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.146/content/NewImages/open-access-icon-orange.png)
Edible insects as a source of biopeptides and their role in immunonutrition
Edible insect species are attracting the attention of the food industry and consumers in Western societies due to their high content and quality of protein, which is starting to be evaluated as source of peptides with immunomodulatory properties.
Food Funct., 2024,15, 2789-2798
https://doi.org/10.1039/D3FO03901C
Ginsenoside – a promising natural active ingredient with steroidal hormone activity
Ginsenosides are a class of natural products with hormone-like activity of triterpenoid saponins and have a variety of pharmacological activities such as anti-aging, immune regulation and cognitive improvement.
Food Funct., 2024,15, 1825-1839
https://doi.org/10.1039/D3FO05484E
Efficacy of antioxidant supplementation in improving endocrine, hormonal, inflammatory, and metabolic statuses of PCOS: a meta-analysis and systematic review
The advantageous effect of antioxidants on PCOS.
Food Funct., 2024,15, 1779-1802
https://doi.org/10.1039/D3FO02824K
Engineered plant extracellular vesicles for natural delivery across physiological barriers
A variety of biochemicals are present in edible plants, and plant extracellular vesicles, as emerging targeted delivery carriers, can penetrate various physiological barriers to exert potential therapeutic effects.
Food Funct., 2024,15, 1737-1757
https://doi.org/10.1039/D3FO03503D
Technological and health properties and main challenges in the production of vegetable beverages and dairy analogs
The consumption of plant-based beverages has been driven by nutritional appeals and as health promoters for individuals with dietary restrictions related to cow's milk or due to ethical, philosophical and environmental factors and lifestyle choices.
Food Funct., 2024,15, 460-480
https://doi.org/10.1039/D3FO04199A
A critical review on intestinal mucosal barrier protection effects of dietary polysaccharides
Studies have shown that the various parts of intestinal barrier can synergistically defend against pathogens in multiple ways.
Food Funct., 2024,15, 481-492
https://doi.org/10.1039/D3FO03412G
Tea, coffee, and caffeine intake and risk of dementia and Alzheimer's disease: a systematic review and meta-analysis of cohort studies
Limited and conflicting evidence exists for the associations between tea, coffee, and caffeine intake and risk of dementia and Alzheimer's disease (AD).
Food Funct., 2024,15, 8330-8344
https://doi.org/10.1039/D4FO01750A
Effects of omega-3, omega-6, and total dietary polyunsaturated fatty acid supplementation in patients with atherosclerotic cardiovascular disease: a systematic review and meta-analysis
The comprehensive meta-analysis of prospective randomized controlled trials (RCTs) to investigate the association between intake of omega-3, omega-6, and total PUFAs was conducted, and cardiovascular events, cardiovascular mortality and all-cause mortality were also presented in this study.
Food Funct., 2024,15, 1208-1222
https://doi.org/10.1039/D3FO02522E
About this collection
This themed collection features recent review articles published in Food & Function.