Manal S. Ebaid, Hoda Atef Abdelsattar Ibrahim, Asmaa F. Kassem and Ahmed Sabt
RSC Adv., 2024,14, 36989-37018
From themed collection:
2024 Reviews in RSC Advances
Abstract
Due to the important role of protein kinases in protein phosphorylation within vital cellular processes, their abnormal function, especially in cancer situations, has underscored their importance in therapy.
Hadil Faris Alotaibi, Fadhil Faez Sead, Farag M. A. Altalbawy, Nawfal Yousif, Ahmed Salih Sahib, Zahraa Saad Abdulali, Mariem Alwan, Mahmood Jasem, Hiba Mushtaq, Adama Faye and Aseel Smerat
RSC Adv., 2026,16, 657-666
Abstract
Sonochemical Cu-DEOD nanocomposite with dabrafenib, enrofloxacin, dipicolinic acid, oxidized pectin. Has anticancer, antimicrobial, antioxidant, anti-inflammatory activities per analyses. Offers platform for enhanced multifunctionality in biomedicine
Younghoon Kim, Jaewon Song, Namkyoung Kim and Taebo Sim
RSC Med. Chem., 2025,16, 2314-2359
From themed collection:
Articles behind our 2025 journal covers
Abstract
Small-molecule and antibody-based targeted therapies for intrahepatic cholangiocarcinoma (iCCA): addressing promising oncogenic molecular alterations, including IDH1, FGFR2, BRAF, HER2, and the PD-1/PD-L1 axis.
Tahir Qadri, Mubashir Aziz, Pervaiz Ali Channar, Syeda Abida Ejaz, Mumtaz Hussain, Hafiz Muhammad Attaullah, Rabail Ujan, Zahid Hussain, Tasneem Zehra, Aamer Saeed, M. R. Shah, Hanan A. Ogaly and Fatimah A. M. Al-Zahrani
RSC Adv., 2023,13, 33826-33843
Abstract
Newly Synthesized bis(3-(2H-benzo[d][1,2,3]triazol-2-yl)-2-(prop-2-yn-1-yloxy)-5-(2,4,4-trimethylpentan-2-yl)phenyl)methane (TAJ1) as potential anti-cancer agent and highly selective NEK-7 inhibitor.
Teja Ram, Ankit Kumar Singh, Adarsh Kumar, Harshwardhan Singh, Prateek Pathak, Maria Grishina, Habibullah Khalilullah, Mariusz Jaremko, Abdul-Hamid Emwas, Amita Verma and Pradeep Kumar
RSC Med. Chem., 2023,14, 1837-1857
Abstract
MEK1/2 are critical components of RAS–RAF–MEK–ERK or MAPK signalling pathway.