Issue 7, 2022

HP(O)Ph2/H2O-promoted hydrodefluorination of trifluoromethyl alkenes

Abstract

An efficient transition-metal-free hydrodefluorination reaction of trifluoromethyl alkenes for accessing gem-difluoroalkenes is developed. It was surprising to find that the phosphoryl anion is able to mediate the defluorination. The successful realization of the reaction could also be attributed to the utility of water as an eco-friendly promoter.

Graphical abstract: HP(O)Ph2/H2O-promoted hydrodefluorination of trifluoromethyl alkenes

Supplementary files

Article information

Article type
Communication
Submitted
13 dec 2021
Accepted
02 mar 2022
First published
04 mar 2022

Green Chem., 2022,24, 2777-2782

HP(O)Ph2/H2O-promoted hydrodefluorination of trifluoromethyl alkenes

X. Chu, L. Sun, Y. Chen, J. Chen, X. Ying, M. Ma and Z. Shen, Green Chem., 2022, 24, 2777 DOI: 10.1039/D1GC04645D

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