Recent advances of Ritter reaction and its synthetic applications

Abstract

In comparison to previous reviews, the present review article provides a comprehensive survey of Ritter reactions from 2014 to 2020, mainly aiming to discuss diverse Ritter reactions and their widely synthetic applications. Notably, the oxidative Ritter-type reactions are presented for the first time, and tandem Ritter reactions and asymmetric Ritter reactions are also highlighted. Furthermore, the systematic summary of the application of Ritter reactions in the total synthesis of natural products and the preparation of drugs, bioactive compounds, and functional molecules is introduced.