Issue 2, 2021

Innovation of hypervalent(iii) iodine in the synthesis of natural products

Abstract

Many natural products have intriguing biological properties that arise from their fascinating chemical structures. Numerous synthetic methods/strategies have been invented to improve the efficiency of natural-product synthesis. A broad group of compounds with diverse functionalities for various applications (e.g., development of new drugs) are available. However, the intrinsic complexity of the structural skeleton and the reactive functional groups on natural products pose tremendous challenges to chemical syntheses. Hypervalent(III) iodine has demonstrated its synthetic versatility by enabling various transformations (e.g., skeletal rearrangement, cyclization and/or cycloaddition and sp3 C–H bond functionalization), which have been utilized widely in the synthesis of natural products. Here, recent innovations of hypervalent(III) iodine in natural-product synthesis are described and discussed.

Graphical abstract: Innovation of hypervalent(iii) iodine in the synthesis of natural products

Article information

Article type
Focus
Submitted
16 okt 2020
Accepted
26 nov 2020
First published
24 dec 2020

New J. Chem., 2021,45, 509-516

Innovation of hypervalent(III) iodine in the synthesis of natural products

Z. Wang, New J. Chem., 2021, 45, 509 DOI: 10.1039/D0NJ05078D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements