Issue 20, 2020

The preparation of (4H)-imidazol-4-ones and their application in the total synthesis of natural products

Abstract

(4H)-Imidazol-4-ones are an important scaffold for a variety of applications, including natural products, medicine, agriculture, and other applications. Over the years, there have been a number of preparations published for the synthesis of imidazol-4-ones. This review discusses the progress made on the synthesis of imidazol-4-ones, and their application towards the total synthesis of a range of imidazol-4-one containing natural products. Emphasis is made on areas of the field that still need progress.

Graphical abstract: The preparation of (4H)-imidazol-4-ones and their application in the total synthesis of natural products

Article information

Article type
Review Article
Submitted
30 jun 2020
Accepted
22 avg 2020
First published
26 avg 2020

Org. Chem. Front., 2020,7, 3284-3311

The preparation of (4H)-imidazol-4-ones and their application in the total synthesis of natural products

K. L. Keel and J. J. Tepe, Org. Chem. Front., 2020, 7, 3284 DOI: 10.1039/D0QO00764A

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