Issue 26, 2016

Surface-enhanced Raman spectroscopy on porous silicon membranes decorated with Ag nanoparticles integrated in elastomeric microfluidic chips

Abstract

A microfluidic sensing device is fabricated by the integration of silver-coated porous silicon membranes as surface enhanced Raman scattering active nanostructures in a PDMS matrix showing plasmon resonances in the visible energy range. The membranes are shaped by defining a suitable pattern of the electrochemically etched silicon using the cover of the elastomeric chip. 4-Mercaptobenzoic acid, used as a probe molecule, shows Raman enhancement larger than 107 in electronic off-resonance conditions. The calibration of the SERS substrate is performed using a Langmuir isotherm fit, evidencing the analyte chemisorption. In order to check the potential of the chip as a multiplexed biosensing platform, model oligonucleotides (polyadenine, polyguanine, polythymine and polycytosine) are analyzed in a multichamber system.

Graphical abstract: Surface-enhanced Raman spectroscopy on porous silicon membranes decorated with Ag nanoparticles integrated in elastomeric microfluidic chips

Supplementary files

Article information

Article type
Paper
Submitted
14 dec 2015
Accepted
10 feb 2016
First published
12 feb 2016

RSC Adv., 2016,6, 21865-21870

Surface-enhanced Raman spectroscopy on porous silicon membranes decorated with Ag nanoparticles integrated in elastomeric microfluidic chips

C. Novara, A. Lamberti, A. Chiadò, A. Virga, P. Rivolo, F. Geobaldo and F. Giorgis, RSC Adv., 2016, 6, 21865 DOI: 10.1039/C5RA26746C

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