Issue 4, 2016

Novel synthesis of N-alkyl amines from tandem coupling of either methylamine or nitroalkane with aldehyde

Abstract

A novel tandem strategy for coupling of either methylamine or nitroalkane with aldehyde has been developed. This is the first demonstration that methylamine or nitroalkane is used as a methylation reagent, fabricating N-alkyl amines. The active Pt NWs allow for the selective preparation of a series of N-alkyl amines with good to excellent yields under mild and environmentally friendly conditions.

Graphical abstract: Novel synthesis of N-alkyl amines from tandem coupling of either methylamine or nitroalkane with aldehyde

Supplementary files

Article information

Article type
Communication
Submitted
17 sep 2015
Accepted
05 nov 2015
First published
05 nov 2015

Chem. Commun., 2016,52, 760-763

Novel synthesis of N-alkyl amines from tandem coupling of either methylamine or nitroalkane with aldehyde

S. Lu, J. Peng, J. Wu, C. Li, X. Cao and H. Gu, Chem. Commun., 2016, 52, 760 DOI: 10.1039/C5CC07807E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements