Issue 48, 2015

Rational design of Au nanorods assemblies for highly sensitive and selective SERS detection of prostate specific antigen

Abstract

A versatile approach for highly sensitive surface-enhanced Raman scattering (SERS) detection of prostate specific antigen (PSA) has been developed based on immune recognition assisted fabrication of gold nanorods (AuNRs) assemblies. Compared with the typical enzyme-linked immunosorbent assay, this SERS immunoassay strategy showed an obviously enhanced sensitivity. The SERS immunoassay for PSA detection has also been successfully applied in diluted human serum samples, showing the promising potential for early diagnosis of diseases in clinical application.

Graphical abstract: Rational design of Au nanorods assemblies for highly sensitive and selective SERS detection of prostate specific antigen

Supplementary files

Article information

Article type
Paper
Submitted
22 jan 2015
Accepted
20 apr 2015
First published
20 apr 2015
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2015,5, 38354-38360

Rational design of Au nanorods assemblies for highly sensitive and selective SERS detection of prostate specific antigen

A. Yang, D. Wang, X. Wang, Y. Han, X. Ke, H. Wang, X. Zhou and L. Ren, RSC Adv., 2015, 5, 38354 DOI: 10.1039/C5RA01322D

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