Issue 45, 2015

Brønsted acid-catalyzed 1,2-fluorine migration with fluoroepoxides

Abstract

A catalytic 1,2-fluorine migration reaction with simple fluoroepoxides at room temperature is reported. Under Brønsted acid catalysis, α-fluorinated ketones are efficiently constructed in the absence of an external fluorine source through a 1,2-fluorine migration reaction. The experimental results indicate that the present 1,2-fluorine migration reaction proceeds via a carbocation intermediate.

Graphical abstract: Brønsted acid-catalyzed 1,2-fluorine migration with fluoroepoxides

  • This article is part of the themed collection: Fluorine

Supplementary files

Article information

Article type
Paper
Submitted
03 jun 2015
Accepted
21 jul 2015
First published
22 jul 2015

Dalton Trans., 2015,44, 19636-19641

Brønsted acid-catalyzed 1,2-fluorine migration with fluoroepoxides

T. Luo, R. Zhang, X. Shen, W. Zhang, C. Ni and J. Hu, Dalton Trans., 2015, 44, 19636 DOI: 10.1039/C5DT02088C

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