Issue 22, 2012

Highly fluorescent benzofuran derivatives of the GFP chromophore

Abstract

Intramolecular cyclization reactions of Green Fluorescent Protein chromophores (GFPc) containing an arylethynyl ortho-substituent at the phenol ring provide new aryl-substituted benzofuran derivatives of the GFPc. Some of these heteroaromatic compounds exhibit significantly enhanced fluorescence at red-shifted emission wavelengths relative to the parent GFPc structure.

Graphical abstract: Highly fluorescent benzofuran derivatives of the GFP chromophore

  • This article is part of the themed collection: Aromaticity

Supplementary files

Article information

Article type
Communication
Submitted
06 jul 2012
Accepted
11 jul 2012
First published
13 jul 2012

RSC Adv., 2012,2, 8243-8249

Highly fluorescent benzofuran derivatives of the GFP chromophore

M. A. Christensen, K. Jennum, P. B. Abrahamsen, E. A. D. Pia, K. Lincke, S. L. Broman, D. B. Nygaard, A. D. Bond and M. B. Nielsen, RSC Adv., 2012, 2, 8243 DOI: 10.1039/C2RA21380J

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