Issue 7, 2019

A new water-soluble cavitand with deeper guest binding properties

Abstract

A new water-soluble cavitand was synthesized which showed isomeric conformations in different solvents. The cavitand displayed multiple conformations – vase, kite, velcrand and intermediate shapes – in CD3OD. The binding properties with hydrophobic (cycloalkanes) and amphiphilic (cycloalkyl carboxylic acids) guests in D2O indicated a deep aromatic pocket.

Graphical abstract: A new water-soluble cavitand with deeper guest binding properties

Supplementary files

Article information

Article type
Research Article
Submitted
11 jan 2019
Accepted
16 feb 2019
First published
25 feb 2019

Org. Chem. Front., 2019,6, 998-1001

Author version available

A new water-soluble cavitand with deeper guest binding properties

F. Rahman, H. Feng and Y. Yu, Org. Chem. Front., 2019, 6, 998 DOI: 10.1039/C9QO00049F

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