Issue 34, 2016

Orthogonal strategy for the synthesis of dual-functionalised β3-peptide based hydrogels

Abstract

We have described a new class of hydrogelator based on helical β3-peptides carrying a bioactive payload. The β3-peptides self-assemble in aqueous solution to form a nanofibrous mesh resulting in a stable hydrogel. The simple design provides the versatility for attaching different functional payloads to the β3-peptide scaffold to develop new materials.

Graphical abstract: Orthogonal strategy for the synthesis of dual-functionalised β3-peptide based hydrogels

  • This article is part of the themed collection: Foldamers

Supplementary files

Article information

Article type
Communication
Submitted
22 jan 2016
Accepted
31 mar 2016
First published
31 mar 2016

Chem. Commun., 2016,52, 5844-5847

Orthogonal strategy for the synthesis of dual-functionalised β3-peptide based hydrogels

K. Kulkarni, S. Motamed, N. Habila, P. Perlmutter, J. S. Forsythe, M. Aguilar and M. P. Del Borgo, Chem. Commun., 2016, 52, 5844 DOI: 10.1039/C6CC00624H

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