Here, we report an iridium-catalyzed reductive β-alkylation of (iso)quinolinium salts with β-chloro ketones, which offers an important complement to the synthesis of functionalized (iso)tetrahydroquinolines.
Metal-free selective C–H thiolation of quinoline, including trifluoromethyl thiolation, aryl thiolation, alkyl thiolation and phenyl selenylation, using N-arylmethyl activation strategies is reported and is applicable to quinoline-based biologically active complex molecules.
A new three-component reaction for mild construction of benzo[d]pyrazolo[4,3-g][1,3]oxazocines is described, which proceeds with readily available feedstocks, catalyst-free conditions, broad substrate, and high step and atom efficiency.
A novel one-pot synthesis of multifunctional organic fluorescent imidates from quinolinium salt derivatives, nitrosoarenes and alcohols was presented. This method had a wide substrate scope and excellent isolated yields.
Bases switch mechanisms – isomeric pyridine and quinoline thiones are easily prepared in an unprecedented regiodivergent manner.