Issue 40, 2012

Polymer–gold nanohybrids with potential use in bimodal MRI/CT: enhancing the relaxometric properties of Gd(iii) complexes

Abstract

We present a new synthetic strategy to produce Gd(III)-decorated gold nanoparticles (AuNPs) for potential use as bimodal contrast agents (CA) for computed X-ray tomography (CT) and magnetic resonance imaging (MRI). The hybrid AuNPs exhibit high molar relaxivities (>12 000 mM−1 s−1 per particle), indicative of highly efficient CT/MRI CAs.

Graphical abstract: Polymer–gold nanohybrids with potential use in bimodal MRI/CT: enhancing the relaxometric properties of Gd(iii) complexes

Supplementary files

Article information

Article type
Communication
Submitted
27 jul 2012
Accepted
30 avg 2012
First published
14 sep 2012

J. Mater. Chem., 2012,22, 21382-21386

Polymer–gold nanohybrids with potential use in bimodal MRI/CT: enhancing the relaxometric properties of Gd(III) complexes

M. Beija, Y. Li, H. T. Duong, S. Laurent, L. V. Elst, R. N. Muller, A. B. Lowe, T. P. Davis and C. Boyer, J. Mater. Chem., 2012, 22, 21382 DOI: 10.1039/C2JM34999J

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