Generation and manipulation of hydrogel microcapsules by droplet-based microfluidics for mammalian cell culture
This critical review discusses microfluidic generation and manipulation of cell-laden hydrogel microcapsules, and their applications for in vitro cell culture.
Microfluidics within a well: an injection-molded plastic array 3D culture platform
A versatile injection-molded platform with fast, robust, and simple liquid patterning capable of 3D co-culture experiments.
Substantially enhanced front illumination photocurrent in porous SnO2 nanorods/networked BiVO4 heterojunction photoanodes
The porous SnO2 nanorods/networked BiVO4 heterojunction is identified as apromising photoanode which exhibits high photocurrent under front illumination.The interplay of porous SnO2 NRs and optimum coverage of BiVO4 lead to high PEC performance.
A hydrostatic pressure-driven passive micropump enhanced with siphon-based autofill function
We present a micropump enhanced with siphon-based autofill function to realize autonomous and continuous perfusion with steady flow over extended time.
Mouse-to-mouse variation in maturation heterogeneity of smooth muscle cells
Immunoblotting cytometry identifies variation in maturation stage of healthy smooth muscle cells, suggesting an important role of cell-to-cell heterogeneity in vascular remodeling.
Paper
Roll-to-roll fabrication of integrated PDMS–paper microfluidics for nucleic acid amplification
High-volume roll-to-roll manufacturing of PDMS–paper microfluidics.
Rapid and label-free identification of single leukemia cells from blood in a high-density microfluidic trapping array by fluorescence lifetime imaging microscopy
Rapid and label-free single-leukemia-cell identification through fluorescence lifetime imaging microscopy (FLIM) in the high-density microfluidic trapping array.
Probing the swelling-dependent mechanical and transport properties of polyacrylamide hydrogels through AFM-based dynamic nanoindentation
The mechanical and transport properties of the polyacrylamide hydrogel are dependent on the swelling ratio.
Microfluidic detection with acoustic spectroscopy (MIDAS) for analysis of insulin formulation stability
Ultrasonic spectroscopy is a viable complement to current techniques used to analyze insulin stability due to its simplicity, lack of sample preparation, and non-destructive properties.
Sensitive and selective detection of the p53 gene based on a triple-helix magnetic probe coupled to a fluorescent liposome hybridization assembly via rolling circle amplification
Developing a sensitive and selective sensing platform for the p53 gene and its mutation analysis is essential and may aid in early cancer screening and assessment of prognosis.
Capture, amplification, and global profiling of microRNAs from low quantities of whole cell lysate
MicroRNAs (miRNAs) are small non-coding RNAs that control gene expression at the post-transcriptional level via a complex regulatory network that requires genome-wide miRNA profiling to dissect.
Length-dependent intracellular bundling of single-walled carbon nanotubes influences retention
Single-walled carbon nanotubes undergo length-dependent intracellular bundling in macrophages that affects retention.
An electrochemical aptasensor for detection of bovine interferon gamma
Bovine tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (MTB) in which it is hard to identify the pathological symptoms.
Design and modeling of electrode networks for code-division multiplexed resistive pulse sensing in microfluidic devices
The analysis of Microfluidic CODES, a code-multiplexed resistive-pulse sensor network for electrical acquisition of spatiotemporal particle manipulation on microfluidic devices.
Size-tunable microvortex capture of rare cells
A wide distribution of cell sizes can be selectively captured by tuning the flow rate in a micro-vortex flow.
In situ mRNA isolation from a microfluidic single-cell array using an external AFM nanoprobe
mRNA probing from single cells within microfluidic arrays, combining the non-destructive and precise-control of a single-cell mRNA probe with sealed microfluidic systems' multifunctional capability.
Microfluidic continuum sorting of sub-populations of tumor cells via surface antibody expression levels
In light of the significance of tumor cell heterogeneity, we describe a facile workflow to isolate distinct groups of tumor cells immunomagnetically, according to their surface-protein expression levels.
Separation and dual detection of prostate cancer cells and protein biomarkers using a microchip device
A micro-aperture platform was developed to separate and detect captured molecular and cellular prostate cancer biomarkers from a single sample.
Paper
Rapid, portable and cost-effective yeast cell viability and concentration analysis using lensfree on-chip microscopy and machine learning
We demonstrate a field-portable and automatic yeast analysis platform that can rapidly measure cell concentration and viability using on-chip microscopy and machine learning.
Three dimensional conjugation of recombinant N-cadherin to a hydrogel for in vitro anisotropic neural growth
Strategy to culture cells in a three dimensional microchanneled hydrogel conjugated with Fc-N-Cad.
Dynamic transcription factor activity networks in response to independently altered mechanical and adhesive microenvironmental cues
Large-scale arrays of transcription factor activity reveal differential responses to chemical and mechanical aspects of the extracellular environment.
Elastomeric free-form blood vessels for interconnecting organs on chip systems
A novel form of a vascular module based on endothelialized PDMS hollow tubes was developed for integrating multiple organs-on-chips.
Rapid bladder cancer cell detection from clinical urine samples using an ultra-thin silicone membrane
A high-throughput strategy capable of differentiating bladder cancer cells from non-cancerous cells based on their respective cellular traction forces.
About this collection
This collection features articles in RSC journals (Lab on a Chip, Analyst, Analytical Methods, Journal of Materials Chemistry A, Journal of Materials Chemistry B, Soft MatterandIntegrative biology) by speakers and track chairs at the 2018 NanoEngineering for Medicine and Biology (NEMB) conference, being held in Los Angeles, USA on 21st-24th August. The conference is chaired by Lab on a Chip Editor-in-Chief, Abraham Lee.