The coronavirus disease 2019 (COVID-19) has spread worldwide with severe health, social, and economic repercussions.
Chemically modifying a natural product can be a powerful tool for studying and optimizing its biological activity. This highlight presents recent examples of applying this approach to investigate natural products that target the opioid receptors.
The mint family (Lamiaceae) produces a wide range of bioactive terpenoids. This review summarizes their biosynthetic pathways and highlights the biosynthesis of menthol, thymol, carnosol, marubiin, forskolin, oridonin and salvinorin.
This review highlights a curated selection of publications utilizing homogeneous gold-catalyzed cycloaddition and cyclization reactions for the total synthesis of natural products reported from 2016 to mid-2023.
Natural products synthesized from ynones are crucial due to their diverse biological activities, structural complexity, and versatility. This review compiles the total synthesis of natural products via ynones as intermediates in development of drugs.