Alpha-lipoic Acid Protects Against Chronic Alcohol Consumption-induced Cardiac Damage by the Aldehyde Dehydrogenase 2–associated PINK/Parkin Pathway

Cheng Shen, Xueheng Chen, Yong Cao, Yanyan Du, Xuan Xu, Qingjing Wu, Lizhi Lin, Yiran Qin, Runqi Meng, Lijun Gan and Jinguo Zhang

Journal of Cardiovascular Pharmacology, 2023, 82, 407
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The many faces of SIRT6 in the retina and retinal pigment epithelium

Jie Cheng, Casey J. Keuthan and Noriko Esumi

Front. Cell Dev. Biol., 2023, 11
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USP18 Stabilized FTO Protein to Activate Mitophagy in Ischemic Stroke Through Repressing m6A Modification of SIRT6

Mingyu Song, Fang Yi, Feiyue Zeng, Lan Zheng, Lei Huang, Xinyu Sun, Qianyi Huang, Jun Deng, Hong Wang and Wenping Gu

Mol Neurobiol, 2024, 61, 6658
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Branched-chain amino acid catabolic defect in vascular smooth muscle cells drives thoracic aortic dissection via mTOR hyperactivation

Liming Yu, Tao Huang, Jikai Zhao, Zijun Zhou, Zijun Cao, Yanbang Chi, Shan Meng, Yuting Huang, Yinli Xu, Lin Xia, Hui Jiang, Zongtao Yin and Huishan Wang

Free Radical Biology and Medicine, 2024, 210, 25
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Mechanism Study of Polydatin in Treating Spinal Cord Injury by Modulating Mitochondrial Membrane Potential Based on Network Pharmacology and Molecular Docking

Bo Dong and Xijing He

Crit Rev Immunol, 2024, 44, 79
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Phytochemicals Targeting Mitophagy to Treat Heart Diseases: Retrospective Insights and Prospective Directions

Qin Dong, Yichan Zhu, Xinghai Zhang, Lu Li, Yi Yang, Chuan Liu and Jianxia Wen

Phytotherapy Research, 2025, 39, 1592
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Inhibition of ferroptosis by icariin treatment attenuates excessive ethanol consumption-induced atrial remodeling and susceptibility to atrial fibrillation, role of SIRT1

Li-Ming Yu, Xue Dong, Tao Huang, Ji-Kai Zhao, Zi-Jun Zhou, Yu-Ting Huang, Yin-Li Xu, Qiu-Sheng Zhao, Zhi-Shang Wang, Hui Jiang, Zong-Tao Yin and Hui-Shan Wang

Apoptosis, 2023, 28, 607
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SIRT3: A potential therapeutic target for liver fibrosis

Yan Ning, Xinyue Dou, Zhichao Wang, Kao Shi, Zeping Wang, Chuan Ding, Xianan Sang, Xiang Zhong, Meiyu Shao, Xin Han and Gang Cao

Pharmacology & Therapeutics, 2024, 257, 108639
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Cardioprotective effects of polydatin against myocardial injury in HFD/stz and high glucose-induced diabetes via a Caveolin 1-dependent mechanism

Wenyan Gong, Ningzhi Zhang, Xiaohong Sun, Yuanyuan Zhang, Yu Wang, Dongxin Lv, Hui Luo, Yingying Liu, Zhen Chen, Qingqing Lei, Gangfeng Zhao, Lin Bai and Qibin Jiao

Phytomedicine, 2024, 135, 156055
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The role of polydatin in inhibiting oxidative stress through SIRT1 activation: A comprehensive review of molecular targets

Ke Liu, Jiaxi Liu, Anjian Xu and Junying Ding

Journal of Ethnopharmacology, 2024, 331, 118322
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Icariin attenuates excessive alcohol consumption-induced susceptibility to atrial fibrillation through SIRT3 signaling

Li-Ming Yu, Xue Dong, Yin-Li Xu, Zi-Jun Zhou, Yu-Ting Huang, Ji-Kai Zhao, Deng-Yue Xu, Xiao-Dong Xue, Qiu-Sheng Zhao, Tao Liu, Zong-Tao Yin, Hui Jiang and Hui-Shan Wang

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2022, 1868, 166483
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Berberine ameliorates chronic intermittent hypoxia‐induced cardiac remodelling by preserving mitochondrial function, role of SIRT6 signalling

Zijun Zhou, Qiusheng Zhao, Yuting Huang, Shan Meng, Xin Chen, Guoxin Zhang, Yanbang Chi, Dengyue Xu, Zongtao Yin, Hui Jiang, Liming Yu and Huishan Wang

J Cellular Molecular Medi, 2024, 28
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AdipoRon ameliorates chronic ethanol induced cardiac necroptosis by reducing ceramide mediated mtROS

Yile Qian, Yanyu Qi, Junyi Lin, Tianyi Zhang, Lingjie Mo, Qiupeng Xue, Nianchang Zheng, Yaqin Niu, Xiaoru Dong, Yan Shi and Yan Jiang

Free Radical Biology and Medicine, 2025, 229, 237
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The multi-dimensional regulatory mechanism of Sirt6 in heart health: From cell death pathways to targeted therapy for cardiovascular diseases

Shifang Zhan, Chenyu Guo, Hua Yan, Guijuan Zheng and Dan Yan

Biochemical and Biophysical Research Communications, 2025, 782, 152561
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Mitophagy in fibrotic diseases: molecular mechanisms and therapeutic applications

Xinyan Cui, Zekun Zhou, Hua Tu, Jianjun Wu, Jian Zhou, Qiao Yi, Ousheng Liu and Xiaohan Dai

Front. Physiol., 2024, 15
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Recent advances of traditional Chinese medicine against cardiovascular disease: overview and potential mechanisms

Junting Dai, Lulu Qiu, Yi Lu and Miao Li

Front. Endocrinol., 2024, 15
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Icariin alleviates renal inflammation and tubulointerstitial fibrosis via Nrf2‐mediated attenuation of mitochondrial damage

Nannan Ding, Shanyue Sun, Shuting Zhou, Zhimei Lv and Rong Wang

Cell Biochemistry & Function, 2024, 42
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Polydatin sensitizes osteosarcoma cells to methotrexate through suppressing the H19/H3K27me3/H3K9me3 mediated folate metabolism regulatory axis

Nan Li, Feng-xiang Pang, Yu-wan Zhou, Shou-chang Ding, Chuan-jian Shi, Rui-jia Wen, Yong-xin Mai, Xian-lin Wu and Jin-fang Zhang

Bioorganic Chemistry, 2025, 162, 108583
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Cellular and molecular biology of sirtuins in cardiovascular disease

Yong-Ping Liu, Ri Wen, Chun-Feng Liu, Tie-Ning Zhang and Ni Yang

Biomedicine & Pharmacotherapy, 2023, 164, 114931
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