Neuroprotective effects of fermented yak milk-derived peptide LYLKPR on H2O2-injured HT-22 cells

Yunlong Jiang, Yuan Qi, Xiaoting Liu, Li Fang, Yawen Gao, Chunlei Liu, Dan Wu, Xiyan Wang, Fanrui Zhao, Ji Wang and Weihong Min

Food Funct., 2022, 13, 12021
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Mechanism of Ser-Ala-Gly-Pro-Ala-Phe treatment with a pulsed electric field to improve ethanol-induced gastric mucosa injury in mice

Liangzi Sun, Mengqi Li, Shuyu Zhang, Zhijie Bao and Songyi Lin

Food Funct., 2022, 13, 6716
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Therapeutic effects of a walnut-derived peptide on NLRP3 inflammasome activation, synaptic plasticity, and cognitive dysfunction in T2DM mice

Yanru Li, Qiao Dang, Yue Shen, Linxin Guo, Chunlei Liu, Dan Wu, Li Fang, Yue Leng and Weihong Min

Food Funct., 2024, 15, 2295
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Bioactive peptides from nuts: A review

Sheccid Acevedo‐Juárez, Daniel Guajardo‐Flores, Erick Heredia‐Olea and Marilena Antunes‐Ricardo

Int J of Food Sci Tech, 2022, 57, 2226
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Impact of Peptide Transport and Memory Function in the Brain

Lihong Cheng, Caiyue Shi, Xixi Li and Toshiro Matsui

Nutrients, 2024, 16, 2947
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Luteolin attenuates trimethyltin chloride-induced hippocampal neurotoxicity through SIRT3/NRF2/HO-1 activation

Ning Ding, Pengyu Wang, Yu Fang, Yuanyuan Hu, Wei Wang, Jiping Wei, Jun Yu and Fei Cai

Neuropharmacology, 2025, 274, 110461
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Discovery and validation of novel neuroprotective peptides from black soybean protein hydrolysates: Dual targeting of cholinergic dysfunction and oxidative stress

Lulu Li, Yang Yang, Bing Wang, Yue Xu, Yan Wang, Xiao-fei Liu, Guang Zhang, Chun-min Ma and Na Zhang

Food Bioscience, 2025, 74, 107920
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Advances on the Antioxidant Peptides from Nuts: A Narrow Review

Fanrui Zhao, Chunlei Liu, Laura Bordoni, Irene Petracci, Dan Wu, Li Fang, Ji Wang, Xiyan Wang, Rosita Gabbianelli and Weihong Min

Antioxidants, 2022, 11, 2020
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Trimethoxyflavones from Ocimum basilicum L. leaves improve long term memory in mice by modulating multiple pathways

Varinder Singh, Kiranpreet Kaur, Sanimardeep Kaur, Richa Shri, Thakur Gurjeet Singh and Manjinder Singh

Journal of Ethnopharmacology, 2022, 295, 115438
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Plant‐derived peptides for the improvement of Alzheimer's disease: Production, functions, and mechanisms

Like Lin, Cong Li, Tingting Li, Jingyi Zheng, Yu Shu, Jingjing Zhang, Yehua Shen and Difeng Ren

Food Frontiers, 2023, 4, 677
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Sirtuins and cognition: implications for learning and memory in neurological disorders

Eric Fagerli, Iris Escobar, Fernando J. Ferrier, Charles W. Jackson, Efrain J. Perez-Lao and Miguel A. Perez-Pinzon

Front. Physiol., 2022, 13
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Food-Derived Peptides: Beneficial CNS Effects and Cross-BBB Transmission Strategies

Zehui Li, Qiao Dang, Peng Wang, Fanrui Zhao, Jianqin Huang, Chongchong Wang, Xingquan Liu and Weihong Min

J. Agric. Food Chem., 2023, 71, 20453
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Molecular Mechanisms of Dietary Bioactive Peptides in Treating Alzheimer’s Disease and Mild Cognitive Impairment by Network Pharmacology and Molecular Docking Analysis

Ruirui Li, Jing Zi, Yifan Hu, Xinlong Li, Qianqian Cao, Yanliu Li, Xiaoyu Wang, Jingyuan Xiong and Guo Cheng

Rejuvenation Research, 2025, 28, 205
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The Potential Effects of Isoleucine Restricted Diet on Cognitive Impairment in High‐Fat‐Induced Obese Mice via Gut Microbiota–Brain Axis

Yuli Wang, Xue Rong, Hui Guan, Fangxin Ouyang, Xing Zhou, Feng Li, Xintong Tan and Dapeng Li

Molecular Nutrition Food Res, 2023, 67
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Recent progress in the preparation of bioactive peptides using simulated gastrointestinal digestion processes

Chao Du, Hansheng Gong, Huawei Zhao and Ping Wang

Food Chemistry, 2024, 453, 139587
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Synergistic Effect of Combined Walnut Peptide and Ginseng Extracts on Memory Improvement in C57BL/6 Mice and Potential Mechanism Exploration

Junxi Fu, Wentian Song, Xiaobing Song, Li Fang, Xiyan Wang, Yue Leng, Ji Wang, Chunlei Liu and Weihong Min

Foods, 2023, 12, 2329
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A Novel Tetrapeptide Ala-Phe-Phe-Pro (AFFP) Derived from Antarctic Krill Prevents Scopolamine-Induced Memory Disorder by Balancing Lipid Metabolism of Mice Hippocampus

Jingqi Yang, Yan Qi, Beiwei Zhu and Songyi Lin

Nutrients, 2024, 16, 1019
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Mitochondrial sirtuin 3 and role of natural compounds: the effect of post-translational modifications on cellular metabolism

Francesca Oppedisano, Salvatore Nesci and Anna Spagnoletta

Critical Reviews in Biochemistry and Molecular Biology, 2024, 59, 199
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Walnut-Derived Peptides Alleviate Learning and Memory Impairments in a Mice Model via Inhibition of Microglia Phagocytose Synapses

Yihang Xing, Haoyuan Shi, Xi Gao, Xinyu Zhu, Dingwen Zhang, Li Fang, Ji Wang, Chunlei Liu, Dan Wu, Xiyan Wang and Weihong Min

J. Agric. Food Chem., 2024, 72, 13654
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Recent advances on the effect of nut consumption on cognitive improvement

Weijie Wu, Ben Niu, Liang Peng, Qi Chen, Huizhi Chen, Hangjun Chen, Wei Xia, Long Jin, Jesus Simal‐Gandara and Haiyan Gao

Food Frontiers, 2023, 4, 1737
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Walnut peptide and ginseng Rg1 co-treatment prevents the loss of neurons and cognitive decline in mouse model with memory impairment

Junxi Fu, Kuzdeuova Damira, Wentian Song, Weijia Li, Li Fang, Yue Leng, Chunlei Liu, Dan Wu and Weihong Min

Food Science and Human Wellness, 2025, 14, 9250156
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A novel neuroprotective peptide against cognitive disorder in mice by regulating hippocampal oxidative stress and synaptic plasticity

Zhiqiang Lu, Yuan Gao, Zhijie Bao and Songyi Lin

Food Bioscience, 2024, 61, 104575
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Nutritional Value and Memory‐Improving Effects of Seven Major Nuts: A Comprehensive Study Using Network Pharmacology and In Vivo Assays

Jiamin Chen, Ben Niu, Ruiling Liu, Chaoyi Shen, Huizhi Chen, Mohamed A. Farag, Hangjun Chen, Qi Chen, Long Jin, Weijie Wu and Haiyan Gao

Food Frontiers, 2026, 7
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Internalization and transport mechanisms of the walnut-derived peptide in bEnd.3 cells

Qiao Dang, Peng Wang, Zehui Li, Chunlei Liu, Fanrui Zhao, Xingquan Liu and Weihong Min

Food Science and Human Wellness, 2026, 15, 9250354
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Ambroxol confers neuroprotection against scopolamine-induced Alzheimer’s-like pathology by modulating oxidative stress, neuroinflammation, and cognitive deficits via Nrf-2/JNK/GSK-3β signaling pathways

Waqas Ahmad, Kyonghwan Choe, Riaz Ahmad, Tae Ju Park and Myeong Ok Kim

Front. Aging Neurosci., 2025, 17
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Antarctic krill peptides improve scopolamine-induced memory impairment in mice

Jingru Zheng, Yuanhong Gao, Jie Ding, Na Sun and Songyi Lin

Food Bioscience, 2022, 49, 101987
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Structure-Activity Relationship of Pine Nut-Derived Peptides and Their Protective Effect on Nerve-Cell Mitochondria

Hongyan Lu, Li Fang, Xiyan Wang, Dan Wu, Chunlei Liu, Xiaoting Liu, Ji Wang, Yawen Gao and Weihong Min

Foods, 2022, 11, 1428
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Targeting sirtuins in neurological disorders: A comprehensive review

Sen-Yu Zhang, Ni Yang, Peng-Hui Hao, Ri Wen and Tie-Ning Zhang

International Journal of Biological Macromolecules, 2025, 292, 139258
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Walnut-Derived Peptides Ameliorate Scopolamine-Induced Memory Impairments in a Mouse Model via Activation of Peroxisome Proliferator-Activated Receptor γ-Mediated Excitotoxicity

Yue Shen, Qiao Dang, Li Fang, Dan Wu, Yanru Li, Fanrui Zhao, Chunlei Liu and Weihong Min

J. Agric. Food Chem., 2024, 72, 12541
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Identification of walnut-derived peptide WNP-8 as a potential therapeutic agent and SIRT2 as a biomarker for cognitive deficiency: A label-free LC-MS/MS proteomics study

Fanrui Zhao, Yu Qi, Weiyu Hou, Chongchong Wang, Shaolong Qi, Chunlei Liu and Weihong Min

International Journal of Biological Macromolecules, 2025, 286, 138432
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5-Heptadecylresorcinol Regulates the Metabolism of Thermogenic Fat and Improves the Thermogenic Capacity of Aging Mice via a Sirtuin 3–Adenosine Monophosphate-Activated Protein Kinase Pathway

Kuiliang Zhang, Tingting Li, Qiang Li, Chenzhipeng Nie, Yujie Sun, Lamei Xue, Yu Wang, Mingcong Fan, Haifeng Qian, Yan Li and Li Wang

J. Agric. Food Chem., 2023, 71, 557
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Interaction between the Neuroprotective and Hyperglycemia Mitigation Effects of Walnut-Derived Peptide LVRL via the Wnt3a/β-Catenin/GSK-3β Pathway in a Type 2 Diabetes Mellitus Model

Fanrui Zhao, Linxin Guo, Ting Huang, Chunlei Liu, Dan Wu, Li Fang and Weihong Min

J. Agric. Food Chem., 2024, 72, 16204
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Network pharmacology and cell experiment demonstrate the neuroprotective potential on hypertension-induced nerve injury of hazelnut-derived peptide YYLLVR

Wentian Song, Haoduo Huang, Jiale Liu, Xiyu Zhao, Li Fang, Chunlei Liu and Weihong Min

Food Bioscience, 2025, 65, 106089
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Qingzhuan dark tea Theabrownin alleviates hippocampal injury in HFD-induced obese mice through the MARK4/NLRP3 pathway

Yining Lei, Yong Chen, Shuo Zhang, Wei Wang, Min Zheng and Ruyi Zhang

Heliyon, 2024, 10, e26923
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Organic–Inorganic Hybrid Synaptic Transistors: Methyl-Silsesquioxanes-Based Electric Double Layer for Enhanced Synaptic Functionality and CMOS Compatibility

Tae-Gyu Hwang, Hamin Park and Won-Ju Cho

Biomimetics, 2024, 9, 157
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5-Heptadecylresorcinol Improves Aging-Associated Hepatic Fatty Acid Oxidation Dysfunction via Regulating Adipose Sirtuin 3

Kuiliang Zhang, Lei Jiang, Lamei Xue, Yu Wang, Yujie Sun, Mingcong Fan, Haifeng Qian, Li Wang and Yan Li

Nutrients, 2024, 16, 978
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Walnut-derived peptides cross the blood–brain barrier and ameliorate Aβ-induced hypersynchronous neural network activity

Weihong Min, Qiao Dang, Zehui Li, Xiyu Zhao, Yue Shen, Li Fang and Chunlei Liu

Food Research International, 2024, 197, 115302
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PRG ameliorates cognitive impairment in Alzheimer's disease mice by regulating β-amyloid and targeting the ERK pathway

Zhiyuan Zhang, Haoran Wu, Shuai Wang, Yuanyuan Li, Pei Yang, Lingchuan Xu, Yuhong Liu and Maoxuan Liu

Phytomedicine, 2024, 130, 155671
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Purification and Identification of Novel Antioxidant Peptides from Hydrolysates of Peanuts (Arachis hypogaea) and Their Neuroprotective Activities

Rui Ma, Jinrong Bai, Yuting Huang, Zhiqiu Wang, Yongju Xu, Yan Huang, Kai Zhong, Yina Huang, Hong Gao and Qian Bu

J. Agric. Food Chem., 2023
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