Development of phenazine-2,3-diol-based photosensitizers: effect of substitution of the cyano group for the nitro group on singlet oxygen generation

Kazuki Ohira, Chih-Hsin Yu, Keiichi Imato and Yousuke Ooyama

New J. Chem., 2023, 47, 16799
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Self-reporting intracellular delivery agent for singlet oxygen

Yiran Li, Lei Wang, Shengli Zhang, Ziang Liu, Rensong Sun, Yuan Qiao and Engin U. Akkaya

Chem. Commun., 2024, 60, 8111
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Overcoming multidrug resistance by a singlet oxygen releasing camptothecin-endoperoxide

Guangyu Zhang, Lei Wang, Yuan Qiao, Feiyan Zhang, Rensong Sun and Engin U. Akkaya

Chem. Commun., 2024, 60, 12197
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Porphyrin–anthracene covalent organic frameworks for sustainable photosterilization

Jing-Xuan Guo, Xue-Mei Gao, Tian-Yue Gu, Hao-Ze Li, Li-Jian Chen, Xu Zhao and Xiu-Ping Yan

J. Mater. Chem. B, 2023, 11, 11094
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N‐Phenyl‐2‐Pyridone‐Derived Endoperoxide Suppressing both Lung Cancer and Idiopathic Pulmonary Fibrosis Progression by Three‐Pronged Action**

Lei Wang, Hao Wu, Ziang Liu, Rensong Sun, Yanping Li, Yu Si, Yun Nie, Yuan Qiao, Xiao Qian, Shengli Zhang, Guangzhe Li, Wen Sun, Yue Pan and Engin U. Akkaya

Angew Chem Int Ed, 2024, 63
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Recent advances in the photophysical detection and delivery of singlet oxygen

Suman Joseph and S.K. Ashok Kumar

Coordination Chemistry Reviews, 2023, 496, 215408
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NIR light-activated programmable drug immobilization and oxygen modulation for enhanced photodynamic and chemo-therapy

Yu Si, Xueying Jiang, Zhigang Gao, Yuan Liang, Wen Sun, Engin U. Akkaya and Lei Wang

Chinese Chemical Letters, 2026, 37, 111195
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The synthesis and anti-cancer efficacy of endoperoxide modified copper sulfide-ferritin nanocages as PDT and PTT agents

Merve Kucukoflaz, Sakine Ulusoy, Bekir Korkmaz, Suleyman Can Ozturk, Melih Akyol, Sibel Berksoy Hayta, Omer Fahrettin Goze, Gunes Esendagli and Fazli Sozmen

J Nanopart Res, 2023, 25
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N‐Phenyl‐2‐Pyridone‐Derived Endoperoxide Suppressing both Lung Cancer and Idiopathic Pulmonary Fibrosis Progression by Three‐Pronged Action**

Lei Wang, Hao Wu, Ziang Liu, Rensong Sun, Yanping Li, Yu Si, Yun Nie, Yuan Qiao, Xiao Qian, Shengli Zhang, Guangzhe Li, Wen Sun, Yue Pan and Engin U. Akkaya

Angewandte Chemie, 2024, 136
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Benzothiazole‐endoperoxide conjugates protect PC12 cells against β‐amyloid‐induced cell death via singlet oxygen mediated oxidative detoxification of fibrils

Hao Wu, Lei Wang, Xiao Qian, Wanwan Wang, Yu Si, Rensong Sun and Engin U. Akkaya

Smart Molecules, 2024, 2
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Singlet Oxygen‐Triggered Release of Nitric Oxide in an Endoperoxide‐Arginine Conjugate

Guangyu Zhang, Lei Wang, Yuan Qiao, Rensong Sun, Ziang Liu and Engin U. Akkaya

Chemistry An Asian Journal, 2024, 19
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Synthesis, Optical and Singlet Oxygen Generation Properties of Phenazinone‐Based Photosensitizer with 5‐Formyl‐2‐Thienyl Substituents

Hiroto Tsuyama, Keiichi Imato and Yousuke Ooyama

Asian J Org Chem, 2025, 14
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A Review of Approaches to the Synthesis of DCL-Based Prostate-Specific Membrane Antigen Ligands

Nikolai Y. Zyk, Nina S. Butakova, Aleksei E. Machulkin and Elena K. Beloglazkina

IJMS, 2026, 27, 4642
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Magnetic nanoparticles covered with polycyclic aromatic hydrocarbons as singlet oxygen carriers for combining photodynamic therapy and magnetic hyperthermia

I.N. Ferreira, M.M. Isikawa, L.H.S. Nunes, M.C. Micheletto and E.J. Guidelli

Journal of Photochemistry and Photobiology A: Chemistry, 2023, 444, 114902
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Targeted Singlet Oxygen Delivery: A Bioorthogonal Metabolic Shunt Linking Hypoxia to Fast Singlet Oxygen Release

Hao Wu, Lei Wang, Yang Wang, Yujie Shao, Guangzhe Li, Kun Shao and Engin U. Akkaya

Angew Chem Int Ed, 2022, 61
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A series of conjugates based on prostate-specific membrane antigen ligands with the chelating agent DOTA: synthesis, radiolabeling, and biological activity

N.S. Butakova, A.A. Uspenskaia, N.Y. Zyk, S.A. Petrov, K.A. Popovicheva, A.S. Lunev, K.A. Petrosova, I.A. Mitrofanov, M.N. Ivashkovskaya, S.A. Evteev, Y.A. Ivanenkov, E.K. Beloglazkina, A.A. Larenkov and A.E. Machulkin

European Journal of Medicinal Chemistry, 2026, 303, 118433
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Targeted Endoperoxides Delivering Singlet Oxygen to Cancer Cell Mitochondria: Exploration of the Therapeutic Potential

Ziang Liu, Lei Wang, Rensong Sun, Hao Wu, Yang Wang, Shengli Zhang, Guangzhe Li, Kun Shao and Engin U. Akkaya

Chemistry A European J, 2024, 30
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Recent progress in the development of singlet oxygen carriers for enhanced photodynamic therapy

Guo Li, Mingmin Wu, Yongxiao Xu, Qi Wang, Jinxia Liu, Xiaobo Zhou, Haiwei Ji, Qu Tang, Xijuan Gu, Shujuan Liu, Yuling Qin, Li Wu and Qiang Zhao

Coordination Chemistry Reviews, 2023, 478, 214979
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Taming of Singlet Oxygen: Towards Artificial Oxygen Carriers Based on 1,4‐Dialkylnaphthalenes

Jin Li, Lei Wang, Jinrong Li, Yujie Shao, Ziang Liu, Guangzhe Li and Engin U. Akkaya

Chemistry A European J, 2022, 28
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Development of small molecule–drug conjugates based on derivatives of natural proteasome inhibitors that exhibit selectivity for PSMA-expressing cancer cells

Takahiro Obara, Nanami Kawano, Kengo Tatsumi, Akira Katsuyama, Kohei Nakajima, Mikako Ogawa and Satoshi Ichikawa

Bioorganic & Medicinal Chemistry, 2024, 108, 117773
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Quinoline Endoperoxides for Mitochondria Targeted Singlet Oxygen Delivery

Yu Si, Lei Wang, Hao Wu, Shoucai Yan, Yang Wang, Xiao Qian, Ziang Liu and Engin U. Akkaya

Chemistry An Asian Journal, 2025, 20
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Targeted Singlet Oxygen Delivery: A Bioorthogonal Metabolic Shunt Linking Hypoxia to Fast Singlet Oxygen Release

Hao Wu, Lei Wang, Yang Wang, Yujie Shao, Guangzhe Li, Kun Shao and Engin U. Akkaya

Angewandte Chemie, 2022, 134
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Androgen receptor blockade and its effect on PSMA-localization in prostate cancer: Implications for radioligand therapy

Flavien Devaux, Kareem Beltagi, Thomas Frank Ermler, Sven Gerlach, Anna Herrmann, Jennifer Kranz, Radu Alexa, Agnieszka Morgenroth, Andreas Theodor Josef Vogg, Laura Schäfer, Najaf Mammadbayli, Matthias Saar and Marco Hoffmann

Biomedicine & Pharmacotherapy, 2025, 193, 118849
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Lutetium-177 Radiolabeled Gold Nanoparticles for Prostate Cancer Theranostics

Adamantia Apostolopoulou, Evangelia-Alexandra Salvanou, Christos Liolios, Stavros Xanthopoulos, Przemysław Koźmiński and Penelope Bouziotis

Nanomaterials, 2026, 16, 441
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