Reusable and highly sensitive SERS immunoassay utilizing gold nanostars and a cellulose hydrogel-based platform

Maria João Oliveira, Inês Cunha, Miguel P. de Almeida, Tomás Calmeiro, Elvira Fortunato, Rodrigo Martins, Luís Pereira, Hugh J. Byrne, Eulália Pereira, Hugo Águas and Ricardo Franco

J. Mater. Chem. B, 2021, 9, 7516
DOI: 10.1039/D1TB01404H

ATR-IR coupled to partial least squares regression (PLSR) for monitoring an encapsulated active molecule in complex semi-solid formulations

Lynda Miloudi, Franck Bonnier, Kevin Barreau, Dominique Bertrand, Xavier Perse, Florent Yvergnaux, Hugh J. Byrne, Igor Chourpa and Emilie Munnier

Analyst, 2018, 143, 2377
DOI: 10.1039/C8AN00547H

Precise diagnosis of tumor cells and hemocytes using ultrasensitive, stable, selective cuprous oxide composite SERS bioprobes assisted with high-efficiency separation microfluidic chips

Yujiao Xie, Lei Xu, Jiahao Zhang, Chenguang Zhang, Yue Hu, Zhouxu Zhang, Guoxin Chen, Shuyan Qi, Xiawei Xu, Jing Wang, Wenzhi Ren, Jie Lin and Aiguo Wu

Mater. Horiz., 2024, 11, 5752
DOI: 10.1039/D4MH00791C

Toward SERS-based point-of-care approaches for therapeutic drug monitoring: the case of methotrexate

Stefano Fornasaro, Silvia Dalla Marta, Marco Rabusin, Alois Bonifacio and Valter Sergo

Faraday Discuss., 2016, 187, 485
DOI: 10.1039/C5FD00173K

Spectral pre and post processing for infrared and Raman spectroscopy of biological tissues and cells

Hugh J. Byrne, Peter Knief, Mark E. Keating and Franck Bonnier

Chem. Soc. Rev., 2016, 45, 1865
DOI: 10.1039/C5CS00440C

Raman micro spectroscopy for in vitro drug screening: subcellular localisation and interactions of doxorubicin

Z. Farhane, F. Bonnier, A. Casey and H. J. Byrne

Analyst, 2015, 140, 4212
DOI: 10.1039/C5AN00256G

Spectropathology for the next generation: Quo vadis?

Hugh J. Byrne, Malgorzata Baranska, Gerwin J. Puppels, Nick Stone, Bayden Wood, Kathleen M. Gough, Peter Lasch, Phil Heraud, Josep Sulé-Suso and Ganesh D. Sockalingum

Analyst, 2015, 140, 2066
DOI: 10.1039/C4AN02036G

Raman imaging for monitoring deuterated squalene-gemcitabine nanomedicines in single living breast cancer cells

Almar Al Assaad, Cherine Alaouta, Didier Desmaële, Emilie Buache, Emilie Fossier, Laurence Van Gulick, Florian Slimano, Sylvain Dukic, Simona Mura, Hamid Morjani and Abdelilah Beljebbar

International Journal of Pharmaceutics, 2024, 667, 124870
DOI: 10.1016/j.ijpharm.2024.124870

Combining Pharmacokinetics and Vibrational Spectroscopy: MCR-ALS Hard-and-Soft Modelling of Drug Uptake In Vitro Using Tailored Kinetic Constraints

David Pérez-Guaita, Guillermo Quintás, Zeineb Farhane, Romá Tauler and Hugh J. Byrne

Cells, 2022, 11, 1555
DOI: 10.3390/cells11091555

Monitoring doxorubicin cellular uptake and trafficking using in vitro Raman microspectroscopy: short and long time exposure effects on lung cancer cell lines

Zeineb Farhane, Franck Bonnier and Hugh J. Byrne

Anal Bioanal Chem, 2017, 409, 1333
DOI: 10.1007/s00216-016-0065-0

Monitoring the biochemical changes occurring to human keratinocytes exposed to solar radiation by Raman spectroscopy

Ulises Lopez‐Gonzalez, Alan Casey and Hugh J. Byrne

Journal of Biophotonics, 2021, 14
DOI: 10.1002/jbio.202000337

Integrating Inertial Microfluidics with SERS Bioprobe for Efficient Enrichment and Accurate Identification of Tumor Cells in Gastric Fluid and Ascites

Jiahao Zhang, Lei Xu, Yue Hu, Li Sun, Yujiao Xie, Xinyu Miao, Aochi Liu, Zhiwei Hou, Yixing Gou, Aiguo Wu and Jie Lin

Anal. Chem., 2025, 97, 13901
DOI: 10.1021/acs.analchem.5c01428

The effect of irradiance and integration time in in vivo normal skin Raman measurements assessed by multivariate statistical analysis

Aspasia Elka, Violetta Moulia, Panagiota Spyridonos, Nikolaos Kourkoumelis and Klaus Gerwert

BSI, 2016, 5, 217
DOI: 10.3233/BSI-160140

An in vitro study of the interaction of the chemotherapeutic drug Actinomycin D with lung cancer cell lines using Raman micro‐spectroscopy

Zeineb Farhane, Franck Bonnier and Hugh J. Byrne

Journal of Biophotonics, 2018, 11
DOI: 10.1002/jbio.201700112

Prediction of viral loads for diagnosis of Hepatitis C infection in human plasma samples using Raman spectroscopy coupled with partial least squares regression analysis

H. Nawaz, N. Rashid, M. Saleem, M. Asif Hanif, M. Irfan Majeed, I. Amin, M. Iqbal, M. Rahman, Ola Ibrahim, S. M. Baig, M. Ahmed, F. Bonnier and H. J. Byrne

J Raman Spectroscopy, 2017, 48, 697
DOI: 10.1002/jrs.5108

Mid-infrared (MIR) Spectroscopy for Quality Analysis of Liquid Foods

Wen-Hao Su and Da-Wen Sun

Food Eng Rev, 2019, 11, 142
DOI: 10.1007/s12393-019-09191-2

In vitro label‐free screening of chemotherapeutic drugs using Raman microspectroscopy: Towards a new paradigm of spectralomics

Zeineb Farhane, Haq Nawaz, Franck Bonnier and Hugh J. Byrne

Journal of Biophotonics, 2018, 11
DOI: 10.1002/jbio.201700258

Spectral encoder to extract the efficient features of Raman spectra for reliable and precise quantitative analysis

Chi Gao, Qi Fan, Peng Zhao, Chao Sun, Ruochen Dang, Yutao Feng, Bingliang Hu and Quan Wang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 312, 124036
DOI: 10.1016/j.saa.2024.124036

Spectralomics – Towards a holistic adaptation of label free spectroscopy

Hugh J. Byrne

Vibrational Spectroscopy, 2024, 132, 103671
DOI: 10.1016/j.vibspec.2024.103671

A new approach to assess post-mortem interval: A machine learning-assisted label-free ATR-FTIR analysis of human vitreous humor

Valentina Notarstefano, Chiara Santoni, Eva Montanari, Francesco Paolo Busardò, Angelo Montana, Giulia Orilisi, Paolo Mariani and Elisabetta Giorgini

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 327, 125326
DOI: 10.1016/j.saa.2024.125326

Advancing Raman spectroscopy from research to clinic: Translational potential and challenges

Swati Tanwar, Santosh Kumar Paidi, Ram Prasad, Rishikesh Pandey and Ishan Barman

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 260, 119957
DOI: 10.1016/j.saa.2021.119957

Quantitative analysis of curcumin-loaded alginate nanocarriers in hydrogels using Raman and attenuated total reflection infrared spectroscopy

Lynda Miloudi, Franck Bonnier, Dominique Bertrand, Hugh J. Byrne, Xavier Perse, Igor Chourpa and Emilie Munnier

Anal Bioanal Chem, 2017, 409, 4593
DOI: 10.1007/s00216-017-0402-y

Microfluidic SERS devices: brightening the future of bioanalysis

Maria João Oliveira, Ana Dalot, Elvira Fortunato, Rodrigo Martins, Hugh J. Byrne, Ricardo Franco and Hugo Águas

Discov Mater, 2022, 2
DOI: 10.1007/s43939-022-00033-3

Fast and Quantitative Analysis of Ediphenphos Residue in Rice Using Surface‐Enhanced Raman Spectroscopy

Shizhuang Weng, Fang Wang, Ronglu Dong, Mengqing Qiu, Jinling Zhao, Linsheng Huang and Dongyan Zhang

Journal of Food Science, 2018, 83, 1179
DOI: 10.1111/1750-3841.14103

Quantitative analysis of solid dosage forms of Atenolol by Raman spectroscopy

Arslan Ali, Haq Nawaz, Muhammad Irfan Majeed and Madiha Ghamkhar

Drug Development and Industrial Pharmacy, 2024, 50, 619
DOI: 10.1080/03639045.2024.2377331

Advances in Biomedical Applications of Raman Microscopy and Data Processing: A Mini Review

Ram Krishna and Ilhami Colak

Analytical Letters, 2023, 56, 576
DOI: 10.1080/00032719.2022.2094391

Raman Spectroscopy for Rapid Evaluation of Surgical Margins during Breast Cancer Lumpectomy

Willie C. Zúñiga, Veronica Jones, Sarah M. Anderson, Alex Echevarria, Nathaniel L. Miller, Connor Stashko, Daniel Schmolze, Philip D. Cha, Ragini Kothari, Yuman Fong and Michael C. Storrie-Lombardi

Sci Rep, 2019, 9
DOI: 10.1038/s41598-019-51112-0

In-situ characterization of porcine fibroblasts in response to silver ions by Raman spectroscopy and liquid scanning transmission electron microscopy

Yuanfeng Zhao, Wei Zhang, Brian Van Devener, Thomas D. Bunch, Anhong Zhou and S. Clay Isom

Talanta, 2022, 246, 123522
DOI: 10.1016/j.talanta.2022.123522

Rapid Decomposition of Epoxy Resins via Raman Spectrometry in Combination with Machine Learning Algorithms

Qiyuan Guan, Kang Guo, Weihong Tan and Yonghong Zhou

Journal of Bioresources and Bioproducts, 2019, 4, 130
DOI: 10.21967/jbb.v4i2.217

Improvement of surface-enhanced Raman scattering detection and imaging by multivariate curve resolution methods

Ziyang Tan, Yuqing Zhang, Benjamin D. Thackray and Jian Ye

Journal of Applied Physics, 2019, 125
DOI: 10.1063/1.5091477

Quantitative analysis of human blood serum using vibrational spectroscopy

Hugh J. Byrne, Franck Bonnier, Jennifer McIntyre and Drishya Rajan Parachalil

Clinical Spectroscopy, 2020, 2, 100004
DOI: 10.1016/j.clispe.2020.100004

Combining fiber optical tweezers and Raman spectroscopy for rapid identification of melanoma

Xun Qiu, Tao He, Xingda Wu, Peng Wang, Xin Wang, Qiuyue Fu, Xianglin Fang, Shaoxin Li and Ying Li

Journal of Biophotonics, 2022, 15
DOI: 10.1002/jbio.202200158

Vibrational spectroscopy as a tool for studying drug-cell interaction: Could high throughput vibrational spectroscopic screening improve drug development?

Lauren E. Jamieson and Hugh J. Byrne

Vibrational Spectroscopy, 2017, 91, 16
DOI: 10.1016/j.vibspec.2016.09.003

Data mining Raman microspectroscopic responses of cells to drugs in vitro using multivariate curve resolution-alternating least squares

David Perez-Guaita, Guillermo Quintas, Zeineb Farhane, Roma Tauler and Hugh J. Byrne

Talanta, 2020, 208, 120386
DOI: 10.1016/j.talanta.2019.120386

Doxorubicin kinetics and effects on lung cancer cell lines using in vitro Raman micro‐spectroscopy: binding signatures, drug resistance and DNA repair

Zeineb Farhane, Franck Bonnier, Orla Howe, Alan Casey and Hugh J. Byrne

Journal of Biophotonics, 2018, 11
DOI: 10.1002/jbio.201700060

Qualitative and quantitative analysis of therapeutic solutions using Raman and infrared spectroscopy

Alaa A. Makki, Franck Bonnier, Renaud Respaud, Fatma Chtara, Ali Tfayli, Clovis Tauber, Dominique Bertrand, Hugh J. Byrne, Elhadi Mohammed and Igor Chourpa

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 218, 97
DOI: 10.1016/j.saa.2019.03.056

Discrimination between oral cancer and healthy cells based on the adenine signature detected by using Raman spectroscopy

Wei‐Yun Dai, Szetsen Lee and Yih‐Chih Hsu

J Raman Spectroscopy, 2018, 49, 336
DOI: 10.1002/jrs.5289

Seeding multivariate algorithms for spectral analysis, a data augmentation approach to enhance analytical performance

M.E. Keating and H.J. Byrne

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 340, 126369
DOI: 10.1016/j.saa.2025.126369

Biomolecular and bioanalytical applications of infrared spectroscopy – A review

Krzysztof B. Beć, Justyna Grabska and Christian W. Huck

Analytica Chimica Acta, 2020, 1133, 150
DOI: 10.1016/j.aca.2020.04.015

Generic Chemometric Models for Metabolite Concentration Prediction Based on Raman Spectra

Abdolrahim Yousefi-Darani, Olivier Paquet-Durand, Almut von Wrochem, Jens Classen, Jens Tränkle, Mario Mertens, Jeroen Snelders, Veronique Chotteau, Meeri Mäkinen, Alina Handl, Marvin Kadisch, Dietmar Lang, Patrick Dumas and Bernd Hitzmann

Sensors, 2022, 22, 5581
DOI: 10.3390/s22155581

Raman Spectroscopy for the Quantitative Analysis of Solid Dosage Forms of the Active Pharmaceutical Ingredient of Febuxostat

Gull Rimsha, Muhammad Shahbaz, Muhammad Irfan Majeed, Haq Nawaz, Nosheen Rashid, Muhammad Waseem Akram, Ifra Shabbir, Kiran Kainat, Aiman Amir, Eiman Sultan, Mulja Munir and Muhammad Imran

ACS Omega, 2023, 8, 41451
DOI: 10.1021/acsomega.3c05243