Issue 49, 2022

Polyurethane–gelatin methacryloyl hybrid ink for 3D printing of biocompatible and tough vascular networks

Abstract

A polyurethane–gelatin methacryloyl (PU–GelMA) hybrid ink was developed as a photo-crosslinkable elastic hydrogel. With the additional acrylic monomer, the ink can be tuned to accommodate elasticity and printability. Attributed to the shear-thinning properties of GelMA, PU–GelMA was preferable for extrusion printing. 3D-constructs were printed by direct extrusion or by using a sacrificial scaffold to resemble the vascular networks. The proliferation of endothelial cells on the PU–GelMA hydrogel indicated decent biocompatibility and potential utilization in artificial vessels.

Graphical abstract: Polyurethane–gelatin methacryloyl hybrid ink for 3D printing of biocompatible and tough vascular networks

Supplementary files

Article information

Article type
Communication
Submitted
16 apr 2022
Accepted
23 máj 2022
First published
23 máj 2022

Chem. Commun., 2022,58, 6894-6897

Polyurethane–gelatin methacryloyl hybrid ink for 3D printing of biocompatible and tough vascular networks

Y. Huang, H. Zhao, X. Wang, X. Liu, Z. Gao, H. Bai, F. Lv, Q. Gu and S. Wang, Chem. Commun., 2022, 58, 6894 DOI: 10.1039/D2CC02176E

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